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Phenotype ontology term - FYPO:0000007 - abnormal S-phase DNA damage checkpoint

Term summary

ID
FYPO:0000007
Name
abnormal S-phase DNA damage checkpoint
Ontology or CV name
Phenotype
Definition
A mitotic cell cycle checkpoint phenotype in which the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

Annotation

Multi-locus phenotype

FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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Single locus phenotype

FYPO:0000007 - abnormal S-phase DNA damage checkpoint

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FYPO:0006436 - abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0003814 - abolished response to S-phase DNA damage checkpoint signaling

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FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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FYPO:0008162 - increased activation of S-phase DNA damage checkpoint

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