Phenotype ontology term - FYPO:0000173 - abnormal mitotic cell cycle DNA replication checkpoint

Term summary

ID

FYPO:0000173

Name

abnormal mitotic cell cycle DNA replication checkpoint

Ontology or CV name

Phenotype

Definition

A cell cycle checkpoint phenotype in which the DNA replication checkpoint in a mitotic cell cycle is abnormal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

• is_a abnormal regulation of G2/M transition of mitotic cell cycle
• is_a abnormal mitotic DNA integrity checkpoint

Annotation