Phenotype ontology term - FYPO:0000297 - microtubule cytoskeleton organization phenotype

FYPO:0001574 - abnormal bipolar mitotic spindle

References:

• PMID:28513584

Genes:

• cut7 (SPAC25G10.07c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7+(wild type)[Overexpression] pkl1+(wild type)[Overexpression]

FYPO:0004088 - abnormal cytoplasmic microtubules

References:

• PMID:12390246
• PMID:27560651

Genes:

• cut1 (SPCC5E4.04)
• mnr2 (SPAC17A2.14)
• SPBC27B12.12c

Genotypes:

• SPBC27B12.12cdelta mnr2delta
• cut1+(wild type) cut1-C(1245-1828)(1-1244 Δaa)[Overexpression]

FYPO:0007080 - abnormal initial meiotic spindle pole body separation in meiosis I

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• klp2 (SPAC664.10)
• nuf2 (SPAC27F1.04c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta klp2delta nuf2-2(unknown) pkl1delta

FYPO:0006040 - abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0000734 - abnormal meiotic spindle

References:

• PMID:17632059
• PMID:27611693

Genes:

• bqt1 (SPAC6G9.13c)
• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• bqt1delta taz1-deltamyb-sad1(Taz1-deltamyb-Sad1(22-514))
• lig4delta taz1delta

FYPO:0000737 - abnormal meiotic spindle assembly

References:

• PMID:17632059
• PMID:27889481

Genes:

• bqt1 (SPAC6G9.13c)
• lig4 (SPCC1183.05c)
• rap1 (SPBC1778.02)
• sad1 (SPBC12D12.01)
• taz1 (SPAC16A10.07c)

Genotypes:

• bqt1delta sad1.2(T3S,S52P aa)
• lig4delta rap1delta
• lig4delta taz1delta

FYPO:0006394 - abnormal meiotic spindle localization

References:

• PMID:17632059

Genes:

• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• lig4delta taz1delta

FYPO:0006388 - abnormal meiotic spindle pole body organization during meiosis I

References:

• PMID:17632059

Genes:

• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• lig4delta taz1delta

FYPO:0004315 - abnormal microtubule cytoskeleton during vegetative growth

References:

• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• dis1 (SPCC736.14)

Genotypes:

• alp14-26(C450R aa) dis1delta

FYPO:0001418 - abnormal microtubule cytoskeleton morphology during vegetative growth

References:

• PMID:8522609

Genes:

• cdc11 (SPCC1739.11c)
• nak1 (SPBC17F3.02)

Genotypes:

• cdc11-19(unknown) orb3-167(C581T nt)

FYPO:0005045 - abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation

References:

• PMID:11069763

Genes:

• bub1 (SPCC1322.12c)
• cid12 (SPCC663.12)
• dma1 (SPAC17G8.10c)

Genotypes:

• bub1delta csp10-439(unknown)
• bub1delta csp10-439(unknown) dma1delta

FYPO:0000338 - abnormal mitotic spindle

References:

• PMID:11927555
• PMID:12065422

Genes:

• cut12 (SPBC649.05)
• fin1 (SPAC19E9.02)
• wee1 (SPCC18B5.03)

Genotypes:

• cut12-1(R536*) fin1delta
• cut12.s11(G71V aa) fin1-ts1(G188E aa)
• fin1-ts1(G188E aa) wee1-50(G850E aa)
• fin1-ts1(G188E aa) wee1-6(unknown)

FYPO:0000131 - abnormal mitotic spindle elongation

References:

• PMID:28513584
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• pkl1 (SPAC3A11.14c)

Genotypes:

• alp14-26(C450R aa) dis1delta
• ase1+(wild type)[Knockdown] cut7delta pkl1delta

FYPO:0001791 - abnormal mitotic spindle pole body duplication

References:

• PMID:2203537

Genes:

• cdc11 (SPCC1739.11c)
• cut1 (SPCC5E4.04)

Genotypes:

• cdc11-123(R947H,T1041I aa) cut1-645(unknown)

FYPO:0001733 - abnormal mitotic spindle pole body separation

References:

• PMID:17036054

Genes:

• dhc1 (SPAC1093.06c)
• klp2 (SPAC664.10)
• nda3 (SPBC26H8.07c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• dhc1delta nda3-KM311(G93E aa)
• klp2delta nda3-KM311(G93E aa)
• nda3-KM311(G93E aa) pkl1delta

FYPO:0007745 - abnormal spindle assembly during meiosis I

References:

• PMID:12606573

Genes:

• bub1 (SPCC1322.12c)
• rec7 (SPCC1753.03c)

Genotypes:

• bub1delta/bub1delta rec7-146(unknown)/rec7-146(unknown)

FYPO:0004510 - abnormal spindle assembly during meiosis II

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta pkl1delta

FYPO:0005652 - abnormal spindle morphology during meiosis I

References:

• PMID:17632059
• PMID:24954111

Genes:

• bqt2 (SPAC1002.06c)
• dhc1 (SPAC1093.06c)
• lig4 (SPCC1183.05c)
• mcp6 (SPBC582.06c)
• taz1 (SPAC16A10.07c)

Genotypes:

• bqt2delta dhc1delta
• bqt2delta mcp6delta
• lig4delta taz1delta

FYPO:0004608 - abnormal spindle pole body morphology during meiosis II

References:

• PMID:25891897

Genes:

• crs1 (SPBC2G2.09c)
• rem1 (SPBC16E9.17c)

Genotypes:

• crs1delta rem1delta

FYPO:0005695 - abolished astral microtubule nucleation during mitosis

References:

• PMID:37783794

Genes:

• cmp7 (SPBC1604.18c)
• ppc89 (SPAC4H3.11c)

Genotypes:

• cmp7delta ppc89-AID(ppc89::pcp89-XTEN16-3×sAID:kanMX6)[Knockdown]

FYPO:0007081 - abolished initial meiotic spindle pole body separation in meiosis I

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• moa1 (SPAC15E1.07c)
• pkl1 (SPAC3A11.14c)
• rec12 (SPAC17A5.11)

Genotypes:

• cut7delta moa1delta pkl1delta
• cut7delta pkl1delta
• cut7delta pkl1delta rec12delta

FYPO:0001683 - abolished mitotic spindle assembly

References:

• PMID:3040264

Genes:

• nda3 (SPBC26H8.07c)
• top2 (SPBC1A4.03c)

Genotypes:

• nda3-KM311(G93E aa) top2-250(cs)(unknown)

FYPO:0004622 - abolished mitotic spindle disassembly

References:

• PMID:32502403

Genes:

• apq12 (SPBC428.04)
• imp1 (SPBC1604.08c)

Genotypes:

• apq12delta imp1delta

FYPO:0006174 - abolished mitotic spindle elongation during anaphase B

References:

• PMID:28513584

Genes:

• cut7 (SPAC25G10.07c)
• klp9 (SPBC15D4.01c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta klp9+(wild type)[Knockdown] pkl1delta

FYPO:0006173 - abolished mitotic spindle elongation during prophase

References:

• PMID:25987607

Genes:

• cut7 (SPAC25G10.07c)
• msd1 (SPBC13E7.06)

Genotypes:

• cut7-21(M394T aa) msd1delta

FYPO:0001734 - abolished mitotic spindle pole body separation

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• moa1 (SPAC15E1.07c)
• pkl1 (SPAC3A11.14c)
• rad21 (SPCC338.17c)
• rec12 (SPAC17A5.11)

Genotypes:

• cut7delta moa1delta pkl1delta rec12delta
• cut7delta pkl1delta rad21-K1(unknown)

FYPO:0006392 - abolished protein localization to meiotic spindle pole body during meiosis I

References:

• PMID:17632059

Genes:

• rap1 (SPBC1778.02)
• taz1 (SPAC16A10.07c)

Genotypes:

• rap1delta taz1-uv3(A606V aa)

FYPO:0007851 - abolished spindle assembly during meiosis I

References:

• PMID:34346498

Genes:

• bqt1 (SPAC6G9.13c)
• sad1 (SPBC12D12.01)

Genotypes:

• bqt1delta sad1.2(T3S,S52P aa)

FYPO:0001978 - bent mitotic spindle

References:

• PMID:11102508
• PMID:22292001

Genes:

• mal3 (SPAC18G6.15)
• moe1 (SPAC637.07)
• rad3 (SPBC216.05)
• skp1 (SPBC409.05)

Genotypes:

• mal3delta moe1delta
• rad3delta skp1-A7(I110T aa)

FYPO:0003327 - curved interphase microtubules

References:

• PMID:33925026

Genes:

• klp6 (SPBC1685.15c)
• nda3 (SPBC26H8.07c)

Genotypes:

• klp6delta nda3-TB101(Y50S aa)

FYPO:0009001 - decreased duration of cytoplasmic microtubule growth events during mitotic interphase

References:

• PMID:24928430

Genes:

• mal3 (SPAC18G6.15)
• rqc2 (SPCC132.01c)

Genotypes:

• mal3delta rqc2delta

FYPO:0007150 - decreased microtubule bundle formation

References:

• PMID:21151990

Genes:

• ase1 (SPAPB1A10.09)
• klp2 (SPAC664.10)

Genotypes:

• ase1delta klp2delta

FYPO:0005682 - decreased microtubule depolymerization during vegetative growth

References:

• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• klp6 (SPBC1685.15c)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta nda3-TB101(Y50S aa)
• klp6delta nda3-TB101(Y50S aa)

FYPO:0005681 - decreased microtubule polymerization

References:

• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• klp6 (SPBC1685.15c)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta nda3-TB101(Y50S aa)
• klp6delta nda3-TB101(Y50S aa)

FYPO:0006885 - decreased protein level at mitotic spindle

References:

• PMID:30463883

Genes:

• alp16 (SPCC4G3.19)
• cut7 (SPAC25G10.07c)
• mal3 (SPAC18G6.15)

Genotypes:

• alp16delta cut7-22(P1021S aa)
• cut7-22(P1021S aa) mal3delta

FYPO:0009057 - decreased rate of microtubule catastrophe involved in meitotic centromere clustering during meiotic prophase I

References:

• PMID:36435910

Genes:

• dis1 (SPCC736.14)
• ndc80 (SPBC11C11.03)

Genotypes:

• ndc80-21(T307A,E379G,L405P aa) nuf2-dis1(18-882)

FYPO:0000903 - decreased rate of microtubule depolymerization during vegetative growth

References:

• PMID:25736293
• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• arp1 (SPBC1347.12)
• nda3 (SPBC26H8.07c)
• num1 (SPBC216.02)

Genotypes:

• alp14delta nda3-TB101(Y50S aa)
• arp1delta num1delta

FYPO:0005703 - decreased rate of microtubule polymerization during vegetative growth

References:

• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta nda3-TB101(Y50S aa)

FYPO:0005343 - decreased rate of mitotic spindle elongation during anaphase B

References:

• PMID:11967147
• PMID:19686686
• PMID:28513584
• PMID:29021344
• PMID:29167352
• PMID:30806623
• PMID:31089172
• PMID:31427431

Genes:

• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• klp9 (SPBC15D4.01c)
• peg1 (SPAC3G9.12)
• pkl1 (SPAC3A11.14c)

Genotypes:

• ase1-S640D,S683D,S688D,S693D(aa) klp9-S>D(S598D,S605D,S611D aa)
• ase1delta klp9-deltaCC1(421-461 Δaa)
• ase1delta klp9-deltaCC2(501-541 Δaa)
• cut7-122(M134T,T290K aa) klp9delta
• cut7-22(P1021S aa) klp9delta pkl1delta
• cut7-22(P1021S aa) pkl1delta
• cut7delta klp9-2(K333M aa) pkl1delta
• cut7delta klp9-deltaCC1(421-461 Δaa) pkl1delta
• cut7delta klp9-deltaCC2(501-541 Δaa) pkl1delta
• cut7delta peg1+(wild type)[Knockdown] pkl1delta
• cut7delta pkl1delta
• dis1delta klp5-Q582P(aa)
• klp5delta klp6delta

FYPO:0004648 - delayed onset of mitotic spindle assembly

References:

• PMID:25103238

Genes:

• cut11 (SPAC1786.03)
• tts1 (SPBC1539.04)

Genotypes:

• cut11-6(T498I aa) tts1delta

FYPO:0006559 - delayed onset of mitotic spindle disassembly

References:

• PMID:36006032

Genes:

• par1 (SPCC188.02)
• par2 (SPAC6F12.12)

Genotypes:

• par1delta par2delta

FYPO:0002636 - delayed onset of mitotic spindle elongation

References:

• PMID:25987607

Genes:

• cut7 (SPAC25G10.07c)
• msd1 (SPBC13E7.06)

Genotypes:

• cut7-21(M394T aa) msd1delta

FYPO:0003566 - delayed onset of mitotic spindle pole body separation

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• nuf2 (SPAC27F1.04c)
• pkl1 (SPAC3A11.14c)
• swi6 (SPAC664.01c)

Genotypes:

• cut7delta nuf2-2(unknown) pkl1delta
• cut7delta pkl1delta swi6delta

FYPO:0005426 - elongated C-shaped vegetative cell with long curved interphase microtubules

References:

• PMID:11739790

Genes:

• cdc25 (SPAC24H6.05)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• cdc25-22(C532Y aa) klp5delta
• cdc25-22(C532Y aa) klp5delta klp6delta
• cdc25-22(C532Y aa) klp6delta

FYPO:0005427 - elongated J-shaped vegetative cell with curved interphase microtubules

References:

• PMID:11739790

Genes:

• cdc10 (SPBC336.12c)
• klp5 (SPBC2F12.13)

Genotypes:

• cdc10-V50(H362Y aa) klp5delta

FYPO:0006049 - fluctuating mitotic spindle length

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0007976 - increased duration of interpolar microtubule growth events during anaphase B

References:

• PMID:35293864

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0007071 - increased rate of mitotic spindle elongation during anaphase A

References:

• PMID:31427431

Genes:

• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)

Genotypes:

• dis1delta klp5-Q582P(aa)

FYPO:0006102 - interphase microtubules absent from cell

References:

• PMID:18061564

Genes:

• mto1 (SPCC417.07c)
• peg1 (SPAC3G9.12)

Genotypes:

• cls1-36(unknown) mto1delta

FYPO:0004511 - long curved interphase microtubules

References:

• PMID:11739790

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0004611 - long interphase microtubules

References:

• PMID:30602572

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0005880 - long interphase microtubules curved around cell end

References:

• PMID:14663827

Genes:

• pom1 (SPAC2F7.03c)
• tea1 (SPCC1223.06)
• tea3 (SPAC6G10.02c)

Genotypes:

• pom1delta tea1delta
• pom1delta tea3delta
• tea1delta tea3delta

FYPO:0007847 - long meiosis I spindle

References:

• PMID:34346498

Genes:

• bqt1 (SPAC6G9.13c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• sad1 (SPBC12D12.01)

Genotypes:

• bqt1delta klp5delta sad1.2(T3S,S52P aa)
• bqt1delta klp6delta sad1.2(T3S,S52P aa)

FYPO:0000733 - long mitotic spindle

References:

• PMID:31427431

Genes:

• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)

Genotypes:

• dis1delta klp5-Q582P(aa)

FYPO:0004307 - long mitotic spindle during metaphase

References:

• PMID:12242294
• PMID:24239120
• PMID:28455357

Genes:

• dcn1 (SPBC839.03c)
• klp5 (SPBC2F12.13)
• mad2 (SPBC20F10.06)
• mal2 (SPAC25B8.14)
• mph1 (SPBC106.01)

Genotypes:

• dcn1delta mad2delta
• klp5delta mad2delta
• mal2-1(E277K aa) mph1+(wild type)[Overexpression]

FYPO:0003787 - long mitotic spindle microtubules protruding beyond spindle pole body

References:

• PMID:25987607
• PMID:26031557
• PMID:29167352

Genes:

• cut7 (SPAC25G10.07c)
• klp2 (SPAC664.10)
• msd1 (SPBC13E7.06)
• pkl1 (SPAC3A11.14c)
• wdr8 (SPBC32H8.09)

Genotypes:

• cut7-21(M394T aa) msd1delta
• cut7delta msd1delta
• klp2delta pkl1delta
• msd1delta pkl1+(wild type)[Overexpression]
• msd1delta pkl1-rigor(G580E)(aa)[Overexpression]
• msd1delta wdr8delta

FYPO:0006391 - meiotic spindle absent from cell during meiosis

References:

• PMID:17632059
• PMID:34346498

Genes:

• alp14 (SPCC895.07)
• bqt1 (SPAC6G9.13c)
• lig4 (SPCC1183.05c)
• sad1 (SPBC12D12.01)
• taz1 (SPAC16A10.07c)

Genotypes:

• alp14-26(C450R aa)[Knockdown] bqt1delta sad1.2(T3S,S52P aa)
• lig4delta taz1delta

FYPO:0003614 - meiotic spindle absent from cell during meiosis II

References:

• PMID:17632059

Genes:

• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• lig4delta taz1delta

FYPO:0002401 - microtubule bundles present in increased numbers

References:

• PMID:22137473
• PMID:38442865

Genes:

• ase1 (SPAPB1A10.09)
• mor2 (SPBP19A11.04c)
• myo51 (SPBC2D10.14c)
• myo52 (SPCC1919.10c)

Genotypes:

• ase1delta mor2-786(A1673G nt)
• myo51delta myo52delta

FYPO:0002004 - microtubules absent from cell

References:

• PMID:10459013
• PMID:16824200

Genes:

• mad2 (SPBC20F10.06)
• nda3 (SPBC26H8.07c)

Genotypes:

• mad2delta nda3-KM311(G93E aa)

FYPO:0003969 - mislocalized mitotic spindle

References:

• PMID:29021344

Genes:

• cut7 (SPAC25G10.07c)
• klp9 (SPBC15D4.01c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7-22(P1021S aa) klp9delta pkl1delta
• cut7delta klp9-2(K333M aa) pkl1delta

FYPO:0002018 - mitotic spindle absent from cell

References:

• PMID:25103238
• PMID:8978687

Genes:

• cut11 (SPAC1786.03)
• dma1 (SPAC17G8.10c)
• nda3 (SPBC26H8.07c)
• tts1 (SPBC1539.04)

Genotypes:

• cut11-6(T498I aa) tts1delta
• dma1::ura4+ nda3-KM311(G93E aa)

FYPO:0006475 - mitotic spindle collapse

References:

• PMID:28513584
• PMID:31532702
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• moa1 (SPAC15E1.07c)
• peg1 (SPAC3G9.12)
• pkl1 (SPAC3A11.14c)

Genotypes:

• alp14-26(C450R aa) dis1delta
• cut7delta moa1delta pkl1delta
• cut7delta peg1+(wild type)[Knockdown] pkl1delta

FYPO:0008007 - mitotic spindle collapse during anaphase B elongation with progressive spindle pole congression

References:

• PMID:19948483

Genes:

• ase1 (SPAPB1A10.09)
• rad21 (SPCC338.17c)

Genotypes:

• ase1delta rad21-K1(unknown)

FYPO:0006171 - mitotic spindle elongation during anaphase A

References:

• PMID:11967147

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0000276 - monopolar mitotic spindle

References:

• PMID:11927555
• PMID:17579515
• PMID:29021344
• PMID:29167352
• PMID:32441227
• PMID:35286199
• PMID:9490630
• PMID:9531532

Genes:

• alp4 (SPBC365.15)
• alp7 (SPAC890.02c)
• ase1 (SPAPB1A10.09)
• cdc25 (SPAC24H6.05)
• cut12 (SPBC649.05)
• cut7 (SPAC25G10.07c)
• fin1 (SPAC19E9.02)
• ght5 (SPCC1235.14)
• hhp1 (SPBC3H7.15)
• hhp2 (SPAC23C4.12)
• klp2 (SPAC664.10)
• mal3 (SPAC18G6.15)
• pim1 (SPBC557.03c)
• pka1 (SPBC106.10)
• pkl1 (SPAC3A11.14c)
• plo1 (SPAC23C11.16)

Genotypes:

• alp4-D440E(aa) plo1delta
• alp7+(wild type)[Overexpression] ase1delta
• alp7-13(R346I,K347R,Y348L aa) cut7delta pkl1delta
• alp7-20(Y344R aa) cut7delta pkl1delta
• cdc25-22(C532Y aa) cut12-1(R536*)
• cdc25-22(C532Y aa) cut12.s11(G71V aa)
• cut7+(wild type) cut7-HS(889-1085 Δaa)
• cut7+(wild type) cut7-ST(1-443 Δaa)
• cut7-22(P1021S aa) klp2delta
• fin1delta pim1-d1(unknown)
• ght5delta hhp1delta plo1delta
• hhp1delta hhp2delta
• mal3+(wild type)[Overexpression] pka1delta

FYPO:0006363 - monopolar spindle during meiosis I

References:

• PMID:17632059
• PMID:32327557

Genes:

• cut7 (SPAC25G10.07c)
• lig4 (SPCC1183.05c)
• pkl1 (SPAC3A11.14c)
• taz1 (SPAC16A10.07c)

Genotypes:

• cut7delta pkl1delta
• lig4delta taz1delta

FYPO:0006390 - multiple meiotic spindles

References:

• PMID:17632059

Genes:

• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• lig4delta taz1delta

FYPO:0003754 - multiple mitotic spindles

References:

• PMID:1655416

Genes:

• cdc2 (SPBC11B10.09)

Genotypes:

• cdc2-33(A177T aa) cdc2-T167E(aa)[Overexpression]

FYPO:0003756 - multiple mitotic spindles with abolished sister chromatid separation

References:

• PMID:2203537
• PMID:8978688

Genes:

• cdc11 (SPCC1739.11c)
• cut1 (SPCC5E4.04)
• cut2 (SPBC14C8.01c)

Genotypes:

• cdc11-123(R947H,T1041I aa) cut1-645(unknown)
• cdc11-123(R947H,T1041I aa) cut2-364(R262*)

FYPO:0007102 - multiple spindles during meiosis II

References:

• PMID:22292001

Genes:

• fbh1 (SPBC336.01)
• rad3 (SPBC216.05)
• skp1 (SPBC409.05)

Genotypes:

• fbh1delta rad3delta
• rad3delta skp1-A7(I110T aa)

FYPO:0007099 - normal spindle elongation in meiosis I

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• klp2 (SPAC664.10)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta klp2delta pkl1delta

FYPO:0003126 - post-anaphase array absent from cell

References:

• PMID:15800064

Genes:

• bgs1 (SPBC19G7.05c)
• mto2 (SPBC902.06)

Genotypes:

• cps1-191(unknown) mto2delta

FYPO:0000732 - short bipolar mitotic spindle

References:

• PMID:31532702

Genes:

• cut7 (SPAC25G10.07c)
• pkl1 (SPAC3A11.14c)
• swi6 (SPAC664.01c)

Genotypes:

• cut7delta pkl1delta swi6delta

FYPO:0007304 - short bipolar mitotic spindle during anaphase

References:

• PMID:31000521

Genes:

• dfp1 (SPCC550.13)
• swi6 (SPAC664.01c)

Genotypes:

• dfp1-CFP-2CD(dfp1-CFP-swi6(69-215)-swi6(69-215)) swi6delta

FYPO:0004395 - short bipolar mitotic spindle during metaphase

References:

• PMID:25987607
• PMID:28513584
• PMID:29021344
• PMID:29167352
• PMID:32723864

Genes:

• alp7 (SPAC890.02c)
• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• klp2 (SPAC664.10)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• klp9 (SPBC15D4.01c)
• msd1 (SPBC13E7.06)
• pkl1 (SPAC3A11.14c)

Genotypes:

• alp7-13(R346I,K347R,Y348L aa) cut7delta pkl1delta
• alp7-20(Y344R aa) cut7delta pkl1delta
• ase1delta klp2delta
• cut7-21(M394T aa) msd1delta
• cut7-22(P1021S aa) klp2delta
• cut7-22(P1021S aa) klp2delta pkl1delta
• cut7-22(P1021S aa) pkl1delta
• cut7delta klp2delta klp5delta klp6delta pkl1delta
• cut7delta klp2delta pkl1delta
• cut7delta klp9+(wild type)[Overexpression] pkl1delta
• cut7delta pkl1delta

FYPO:0002760 - short cytoplasmic microtubules

References:

• PMID:15177031

Genes:

• tea2 (SPBC1604.20c)
• tip1 (SPAC3C7.12)

Genotypes:

• tea2delta tip1delta

FYPO:0006103 - short interphase microtubules

References:

• PMID:24928430
• PMID:25254656

Genes:

• asp1 (SPCC1672.06c)
• mal3 (SPAC18G6.15)
• rps1801 (SPBC16D10.11c)
• rqc2 (SPCC132.01c)

Genotypes:

• asp1-H397A(aa) mal3delta
• mal3delta rps1801delta
• mal3delta rqc2delta

FYPO:0003429 - short interphase microtubules present in decreased numbers

References:

• PMID:11102508
• PMID:14767070

Genes:

• atb2 (SPBC800.05c)
• mal3 (SPAC18G6.15)
• mmd1 (SPAC30C2.02)
• moe1 (SPAC637.07)

Genotypes:

• ban5-4(unknown) mmd1-1(E66L aa)
• mal3delta moe1delta

FYPO:0007846 - short meiotic spindle during anaphase I

References:

• PMID:34346498

Genes:

• ase1 (SPAPB1A10.09)
• bqt1 (SPAC6G9.13c)
• sad1 (SPBC12D12.01)

Genotypes:

• ase1delta bqt1delta sad1.2(T3S,S52P aa)

FYPO:0007755 - short meiotic spindle during metaphase I

References:

• PMID:32723864

Genes:

• ase1 (SPAPB1A10.09)
• klp2 (SPAC664.10)

Genotypes:

• ase1delta/ase1delta klp2delta/klp2delta

FYPO:0005797 - short microtubule bundle

References:

• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• mal3 (SPAC18G6.15)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta nda3-TB101(Y50S aa)
• mal3delta nda3-TB101(Y50S aa)

FYPO:0007969 - short-lived long mitotic spindle microtubules protruding beyond spindle pole body

References:

• PMID:26031557

Genes:

• cut7 (SPAC25G10.07c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta pkl1delta

FYPO:0006364 - spindle microtubules detached from spindle pole body during meiosis I

References:

• PMID:17632059

Genes:

• lig4 (SPCC1183.05c)
• taz1 (SPAC16A10.07c)

Genotypes:

• lig4delta taz1delta

FYPO:0004609 - spindle pole bodies present in increased numbers during meiosis

References:

• PMID:15992541

Genes:

• dot2 (SPBC651.05c)
• pcp1 (SPAC6G9.06c)

Genotypes:

• dot2-439(E33*)/dot2-439(E33*) pcp1+(wild type)[Knockdown]/pcp1+(wild type)[Knockdown]

FYPO:0007849 - spindle self-assembly during meiosis I

References:

• PMID:34346498

Genes:

• ase1 (SPAPB1A10.09)
• bqt1 (SPAC6G9.13c)
• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• sad1 (SPBC12D12.01)

Genotypes:

• ase1delta bqt1delta sad1.2(T3S,S52P aa)
• bqt1delta dis1delta sad1.2(T3S,S52P aa)
• bqt1delta klp5delta sad1.2(T3S,S52P aa)
• bqt1delta klp6delta sad1.2(T3S,S52P aa)
• bqt1delta sad1.2(T3S,S52P aa)

FYPO:0006884 - thick mitotic spindle during mitotic metaphase

References:

• PMID:30463883
• PMID:33946513

Genes:

• cut7 (SPAC25G10.07c)
• dri1 (SPAC17H9.04c)
• klp2 (SPAC664.10)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7-22(P1021S aa) dri1delta
• cut7-22(P1021S aa) klp2delta
• cut7-22(P1021S aa) pkl1delta

FYPO:0007961 - transient abrupt spindle length decrease at anaphase onset

References:

• PMID:24239120

Genes:

• ase1 (SPAPB1A10.09)
• klp5 (SPBC2F12.13)

Genotypes:

• ase1delta klp5delta

FYPO:0001574 - abnormal bipolar mitotic spindle

References:

• PMID:11432827

Genes:

• alp14 (SPCC895.07)

Genotypes:

• alp14-1270(unknown)

FYPO:0004532 - abnormal cell cycle arrest in mitotic M phase with abnormal spindle

References:

• PMID:11683390

Genes:

• dis1 (SPCC736.14)

Genotypes:

• dis1-203(S265*)

FYPO:0004022 - abnormal cell cycle arrest in mitotic metaphase with long polar microtubules

References:

• PMID:16079915
• PMID:8978689

Genes:

• dam1 (SPAC589.08c)
• dis2 (SPBC776.02c)

Genotypes:

• dam1+(wild type)[Overexpression]
• dis2-11(R245Q aa)

FYPO:0000234 - abnormal cytoplasmic interphase microtubule nucleation

References:

• PMID:15004232
• PMID:24006493
• PMID:30427751

Genes:

• mto1 (SPCC417.07c)
• mzt1 (SPAC9G1.15c)
• rsp1 (SPBC11B10.05c)

Genotypes:

• mto1delta
• mzt1+(wild type)[Knockdown]
• rsp1delta

FYPO:0007975 - abnormal distribution of interpolar microtubule rescue during anaphase B

References:

• PMID:35293864

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0005690 - abnormal eMTOC assembly

References:

• PMID:15004232

Genes:

• gfh1 (SPBC211.06)

Genotypes:

• gfh1delta

FYPO:0007501 - abnormal horsetail-astral microtubule organization

References:

• PMID:16111942

Genes:

• mcp6 (SPBC582.06c)

Genotypes:

• mcp6delta

FYPO:0006396 - abnormal iMTOC assembly

References:

• PMID:16481403

Genes:

• alp7 (SPAC890.02c)

Genotypes:

• alp7delta

FYPO:0007080 - abnormal initial meiotic spindle pole body separation in meiosis I

References:

• PMID:27889481

Genes:

• bqt1 (SPAC6G9.13c)

Genotypes:

• bqt1delta

FYPO:0006101 - abnormal interphase microtubules

References:

• PMID:16111942
• PMID:2908246
• PMID:8621436

Genes:

• cdc13 (SPBC582.03)
• mto1 (SPCC417.07c)
• rpn12 (SPBC16G5.01)

Genotypes:

• cdc13-117(C379Y aa)
• mto1delta
• mts3-1(unknown)

FYPO:0007981 - abnormal interpolar microtubule length distribution during anaphase B

References:

• PMID:15689489

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0006040 - abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)

Genotypes:

• klp5delta

FYPO:0000734 - abnormal meiotic spindle

References:

• PMID:10521402
• PMID:10623474
• PMID:11901107
• PMID:20383139
• PMID:27611693
• PMID:29123917

Genes:

• bqt1 (SPAC6G9.13c)
• dot2 (SPBC651.05c)
• mat1-Mi (SPBC23G7.17c)
• mei4 (SPBC32H8.11)
• plo1 (SPAC23C11.16)
• rad3 (SPBC216.05)
• taz1 (SPAC16A10.07c)
• ubi4 (SPBC337.08c)

Genotypes:

• bqt1delta
• dot2+(wild type)/dot2-439(E33*)
• mat1-Mi+(wild type)/mat1-Mm143(unknown)
• mei4+(wild type)/mei4-512(unknown)
• mei4+(wild type)/mei4-550(unknown)
• mei4+(wild type)/mei4-636(unknown)
• plo1+(wild type)[Knockdown]
• rad3-136(unknown)[Null]/rad3-136(unknown)[Null]
• taz1-deltamyb-sad1(Taz1-deltamyb-Sad1(22-514))
• ubi4-H45(M1V aa)

FYPO:0000737 - abnormal meiotic spindle assembly

References:

• PMID:11901107
• PMID:12759375
• PMID:17632059
• PMID:26058898

Genes:

• bqt1 (SPAC6G9.13c)
• mat1-Mi (SPBC23G7.17c)
• meu14 (SPBC1347.03)
• rap1 (SPBC1778.02)
• taz1 (SPAC16A10.07c)

Genotypes:

• bqt1delta
• mat1-Mi+(wild type)/mat1-Mm143(unknown)
• meu14delta
• rap1-DD337AA(D337A,D338A aa)
• taz1-uv3(A606V aa)

FYPO:0006388 - abnormal meiotic spindle pole body organization during meiosis I

References:

• PMID:17632059
• PMID:22438582

Genes:

• bqt1 (SPAC6G9.13c)
• cdc2 (SPBC11B10.09)
• taz1 (SPAC16A10.07c)

Genotypes:

• bqt1delta
• cdc2-asM17(K79E,F84G aa)[Knockdown]
• taz1delta

FYPO:0005558 - abnormal microtubule bundle

References:

• PMID:15689489
• PMID:16481403
• PMID:19879140
• PMID:24790093
• PMID:30427751

Genes:

• alp14 (SPCC895.07)
• alp7 (SPAC890.02c)
• ase1 (SPAPB1A10.09)
• rsp1 (SPBC11B10.05c)

Genotypes:

• alp14deltaTOG(1-500 Δaa)
• alp7delta
• ase1delta
• mia1delta151-300(aa)
• rsp1delta

FYPO:0005565 - abnormal microtubule bundle during G0 to G1 transition

References:

• PMID:26124291

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0002761 - abnormal microtubule bundle formation

References:

• PMID:9078365

Genes:

• pab1 (SPAC227.07c)

Genotypes:

• pab1::ura4+

FYPO:0007126 - abnormal microtubule bundle formation during mitotic spindle assembly

References:

• PMID:31615768

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0002399 - abnormal microtubule cytoskeleton

References:

• PMID:23697806

Genes:

• alg6 (SPBC342.01c)
• bst1 (SPAC824.02)
• cph1 (SPAC16C9.05)
• erd1 (SPAC227.01c)
• iec1 (SPAC144.02)
• kap111 (SPAC22G7.02)
• lac1 (SPBC3E7.15c)
• meu29 (SPAC25H1.05)
• mga2 (SPAC26H5.05)
• nop52 (SPBC9B6.07)
• rpl3001 (SPAC9G1.03c)
• rpl3202 (SPAC3H5.10)
• swr1 (SPAC11E3.01c)
• ubr1 (SPBC19C7.02)
• vps71 (SPBC29A3.05)
• yaf9 (SPAC17G8.07)

Genotypes:

• alg6delta
• bst1delta
• cph1delta
• erd1delta
• iec1delta
• kap111delta
• lac1delta
• meu29delta
• mga2delta
• nop52delta
• rpl3001delta
• rpl3202delta
• swr1delta
• ubr1delta
• vps71delta
• yaf9delta

FYPO:0004315 - abnormal microtubule cytoskeleton during vegetative growth

References:

• PMID:18495844

Genes:

• orb6 (SPAC821.12)

Genotypes:

• orb6-25(unknown)

FYPO:0003065 - abnormal microtubule cytoskeleton morphology during mating

References:

• PMID:23755176

Genes:

• mal3 (SPAC18G6.15)

Genotypes:

• mal3delta

FYPO:0004246 - abnormal microtubule cytoskeleton morphology during meiotic prophase I

References:

• PMID:11907273

Genes:

• dlc1 (SPAC1805.08)

Genotypes:

• dlc1delta

FYPO:0003625 - abnormal microtubule cytoskeleton morphology during mitotic interphase

References:

• PMID:12234926
• PMID:12456722
• PMID:25373780

Genes:

• aah3 (SPCC63.02c)
• ada2 (SPCC24B10.08c)
• ago1 (SPCC736.11)
• ale1 (SPBC16A3.10)
• apl4 (SPCP1E11.06)
• apl5 (SPAC144.06)
• aps3 (SPAC30D11.05)
• arf6 (SPBC1539.08)
• arp42 (SPAC23D3.09)
• ash2 (SPBC13G1.08c)
• bag101 (SPBC16G5.11c)
• bmt2 (SPAC630.10)
• cao2 (SPBC1289.16c)
• cbp1 (SPBC1105.04c)
• ccq1 (SPCC188.07)
• ccr1 (SPBC29A10.01)
• cdt2 (SPAC17H9.19c)
• cid12 (SPCC663.12)
• clr5 (SPAC29B12.08)
• coq5 (SPCC4G3.04c)
• cox19 (SPCC1672.04c)
• cph1 (SPAC16C9.05)
• cph2 (SPAC2F7.07c)
• cps3 (SPAC3A11.02)
• crf1 (SPAC22H10.11c)
• csn1 (SPBC215.03c)
• csn2 (SPAPB17E12.04c)
• csr101 (SPAC589.09)
• csx1 (SPAC17A2.09c)
• ctp1 (SPCC338.08)
• cuf1 (SPAC31A2.11c)
• cyb502 (SPBC29A10.16c)
• cys11 (SPBC36.04)
• dep1 (SPBC21C3.02c)
• did4 (SPAC4F8.01)
• dph3 (SPAC8F11.02c)
• ecm31 (SPAC5H10.09c)
• efc25 (SPBC336.03)
• elp2 (SPCC895.06)
• elp3 (SPAC29A4.20)
• elp4 (SPCC11E10.06c)
• elp6 (SPBC3H7.10)
• emc6 (SPCC1020.11c)
• emr1 (SPAC8C9.19)
• erd1 (SPAC227.01c)
• erg4 (SPAC20G4.07c)
• erp2 (SPAC17A5.08)
• esl1 (SPBC2F12.03c)
• etf1 (SPAC27D7.06)
• exo2 (SPAC17A5.14)
• fft2 (SPCC1235.05c)
• fit1 (SPBC543.08)
• fkh2 (SPBC16G5.15c)
• gas5 (SPAC11E3.13c)
• gcn5 (SPAC1952.05)
• gfh1 (SPBC211.06)
• git3 (SPCC1753.02c)
• gma12 (SPCC736.04c)
• hem14 (SPAC1F5.07c)
• hem25 (SPAC823.10c)
• kap113 (SPCC1322.06)
• kti12 (SPAC30.02c)
• liz1 (SPBC2G2.01c)
• lon1 (SPAC22F3.06c)
• ltc1 (SPBC20F10.07)
• ltv1 (SPAC3F10.17)
• mak1 (SPAC1834.08)
• mal3 (SPAC18G6.15)
• mcl1 (SPAPB1E7.02c)
• med18 (SPAC5D6.05)
• med20 (SPAC17G8.05)
• met14 (SPAC1782.11)
• meu34 (SPAC3A12.03c)
• mms1 (SPAC3H8.05c)
• mob2 (SPCC970.04c)
• mok11 (SPAC1527.01)
• mor2 (SPBP19A11.04c)
• mpg2 (SPBC13G1.02)
• mpn1 (SPAC23C11.10)
• mre11 (SPAC13C5.07)
• mrpl1 (SPAC1610.02c)
• mss116 (SPBC691.04)
• msy1 (SPCC1183.11)
• naa30 (SPBC15D4.06)
• nab3 (SPAC3H8.09c)
• nas6 (SPAC6C3.08)
• nat2 (SPBC106.07c)
• nif1 (SPBC23G7.04c)
• nod1 (SPAC12B10.10)
• nts1 (SPCC24B10.19c)
• ola1 (SPAC27E2.03c)
• osr2 (SPCC965.06)
• oxa102 (SPBP4H10.03)
• oxs1 (SPBC29A10.12)
• paf1 (SPAC664.03)
• pep3 (SPCC790.02)
• pex5 (SPBC725.07)
• pfd1 (SPBC1D7.01)
• pfd2 (SPAC227.10)
• pfd3 (SPAC3H8.07c)
• pfd5 (SPBC215.02)
• pka1 (SPBC106.10)
• pmt1 (SPBC19C2.02)
• png1 (SPAC3G9.08)
• pof3 (SPCC338.16)
• ppk13 (SPAC3H1.13)
• puf4 (SPAC6G9.14)
• pxr1 (SPAC890.05)
• qcr6 (SPBC16C6.08c)
• rad50 (SPAC1556.01c)
• rad51 (SPAC644.14c)
• rad55 (SPAC3C7.03c)
• rdh54 (SPAC22F3.03c)
• rea1 (SPAC227.17c)
• red1 (SPAC1006.03c)
• rep2 (SPBC2F12.11c)
• rgp1 (SPBC23E6.08)
• ria1 (SPCC553.08c)
• rpl3001 (SPAC9G1.03c)
• rpl3702 (SPCC1223.05c)
• rpl801 (SPAC1F7.13c)
• rpn10 (SPAC637.10c)
• rps1002 (SPBP22H7.08)
• rqt2 (SPBC13G1.10c)
• rrf1 (SPBC1709.09)
• rrp2 (SPBC23E6.02)
• rsc4 (SPBC1734.15)
• rxt2 (SPBC428.06c)
• ryh1 (SPAC4C5.02c)
• sal3 (SPCC1840.03)
• sbh1 (SPBC2G2.03c)
• sce3 (SPBC18H10.04c)
• sco1 (SPBC119.06)
• ser2 (SPBC3H7.07c)
• set1 (SPCC306.04c)
• sin1 (SPAPYUG7.02c)
• slx9 (SPAPB21F2.03)
• snz1 (SPAC29B12.04)
• sol1 (SPBC30B4.04c)
• spf1 (SPCC594.05c)
• spo7 (SPAC6G9.04)
• sro7 (SPAC1F3.03)
• ssa1 (SPAC13G7.02c)
• sto1 (SPBC16G5.07c)
• svf1 (SPCC584.11c)
• swd1 (SPAC23H3.05c)
• tdh1 (SPBC32F12.11)
• tea1 (SPCC1223.06)
• tea2 (SPBC1604.20c)
• tea4 (SPBC1706.01)
• tel1 (SPCC23B6.03c)
• thi201 (SPBP8B7.18c)
• tho7 (SPCC24B10.11c)
• tip1 (SPAC3C7.12)
• tlg2 (SPAC823.05c)
• tom7 (SPBC27B12.10c)
• trm2 (SPAC4G8.07c)
• trp1322 (SPCC1322.03)
• trs8502 (SPBC1734.07c)
• tsf1 (SPBC800.07c)
• tup11 (SPAC18B11.10)
• tup12 (SPAC630.14c)
• ubi1 (SPAC11G7.04)
• ulp2 (SPAC17A5.07c)
• upf3 (SPAC13G7.03)
• utp502 (SPCC1450.03)
• vps1 (SPAC767.01c)
• vps16 (SPAC824.05)
• vps25 (SPBC4B4.06)
• vps32 (SPAC1142.07c)
• vps36 (SPBC3B9.09)
• vps66 (SPAC1783.02c)
• wat1 (SPBC21B10.05c)
• wbp4 (SPBC18H10.07)
• wis1 (SPBC409.07c)
• yox1 (SPBC21B10.13c)
• ypa1 (SPAC4F10.04)
• zfs1 (SPBC1718.07c)
• SPAC15E1.02c
• SPAC1687.08
• SPAC343.20
• SPAC5H10.04
• SPAPB1A10.08
• SPBC1604.12
• SPBC16E9.15
• SPBC17A3.05c
• SPBC1861.05
• SPBC685.03

Genotypes:

• SPAC15E1.02cdelta
• SPAC1687.08delta
• SPAC343.20delta
• SPAC5H10.04delta
• SPAPB1A10.08delta
• SPBC1604.12delta
• SPBC16E9.15delta
• SPBC17A3.05cdelta
• SPBC1861.05delta
• SPBC685.03delta
• aah3delta
• ada2delta
• ago1delta
• ale1delta
• apl4delta
• apl5delta
• aps3delta
• arf6delta
• arp42delta
• ash2delta
• bag101delta
• bmt2delta
• cao2delta
• cbp1delta
• ccq1delta
• ccr1delta
• cdt2delta
• cid12delta
• clr5delta
• coq5delta
• cox19delta
• cph1delta
• cph2delta
• cps3delta
• crf1delta
• csn1delta
• csn2delta
• csr101delta
• csx1delta
• ctp1delta
• cuf1delta
• cyb502delta
• cys11delta
• dep1delta
• did4delta
• dph3delta
• ecm31delta
• efc25delta
• elp2delta
• elp3delta
• elp4delta
• elp6delta
• emc6delta
• emr1delta
• erd1delta
• erg4delta
• erp2delta
• esl1delta
• etf1delta
• exo2delta
• fft2delta
• fit1delta
• fkh2delta
• gas5delta
• gcn5delta
• gfh1delta
• git3delta
• gma12delta
• hem14delta
• hem25delta
• kap113delta
• kti12delta
• liz1delta
• lon1delta
• ltc1delta
• ltv1delta
• mak1delta
• mal3delta
• mcl1delta
• med18delta
• med20delta
• met14delta
• meu34delta
• mms1delta
• mob2delta
• mok11delta
• mor2-786(A1673G nt)
• mpg2delta
• mpn1delta
• mre11delta
• mrpl1delta
• mss116delta
• msy1delta
• naa30delta
• nab3delta
• nas6delta
• nat2delta
• nif1delta
• nod1delta
• nts1delta
• ola1delta
• osr2delta
• oxa102delta
• oxs1delta
• paf1delta
• pep3delta
• pex5delta
• pfd1delta
• pfd2delta
• pfd3delta
• pfd5delta
• pka1delta
• pmt1delta
• png1delta
• pof3delta
• ppk13delta
• puf4delta
• pxr1delta
• qcr6delta
• rad50delta
• rad51delta
• rad55delta
• rdh54delta
• rea1delta
• red1delta
• rep2delta
• rgp1delta
• ria1delta
• rpl3001delta
• rpl3702delta
• rpl801delta
• rpn10delta
• rps1002delta
• rqt2delta
• rrf1delta
• rrp2delta
• rsc4delta
• rxt2delta
• ryh1delta
• sal3delta
• sbh1delta
• sce3delta
• sco1delta
• ser2delta
• set1delta
• sin1delta
• slx9delta
• snz1delta
• sol1delta
• spf1delta
• spo7delta
• sro7delta
• ssa1delta
• sto1delta
• svf1delta
• swd1delta
• tdh1delta
• tea1delta
• tea2delta
• tea4delta
• tel1delta
• thi201delta
• tho7delta
• tip1delta
• tlg2delta
• tom7delta
• trm2delta
• trp1322delta
• trs8502delta
• tsf1delta
• tup11delta
• tup12delta
• ubi1delta
• ulp2delta
• upf3delta
• utp502delta
• vps16delta
• vps1delta
• vps25delta
• vps32delta
• vps36delta
• vps66delta
• wat1delta
• wbp4delta
• wis1delta
• yox1delta
• ypa1delta
• zfs1delta

FYPO:0001418 - abnormal microtubule cytoskeleton morphology during vegetative growth

References:

• PMID:10526238
• PMID:12376568
• PMID:15302827
• PMID:15797925
• PMID:8187760
• PMID:8522609
• PMID:8774852
• PMID:8886983
• PMID:9450991

Genes:

• act1 (SPBC32H8.12c)
• alp1 (SPBC11C11.04c)
• bgs4 (SPCC1840.02c)
• cka1 (SPAC23C11.11)
• cps3 (SPAC3A11.02)
• fkh2 (SPBC16G5.15c)
• mug70 (SPAC24C9.05c)
• nak1 (SPBC17F3.02)
• ned1 (SPAC1952.13)
• orb6 (SPAC821.12)
• sts5 (SPCC16C4.09)
• tef102 (SPAC23A1.10)
• SPBP4H10.07

Genotypes:

• SPBP4H10.07+(wild type)[Overexpression]
• alp1+(wild type)[Overexpression]
• cps3+(wild type)[Overexpression]
• cps8-188(G273D aa)
• fkh2delta
• mug70+(wild type)[Overexpression]
• ned1+(wild type)[Overexpression]
• orb11-(unknown)
• orb3-167(C581T nt)
• orb4-(unknown)
• orb5-19(unknown)
• orb6-25(unknown)
• sts5-7(unknown)
• tef102+(wild type)[Overexpression]

FYPO:0000054 - abnormal microtubule cytoskeleton organization

References:

• PMID:11696322

Genes:

• for3 (SPCC895.05)

Genotypes:

• for3delta

FYPO:0001350 - abnormal microtubule cytoskeleton organization during vegetative growth

References:

• PMID:16611238
• PMID:17021256
• PMID:17476213
• PMID:19606211
• PMID:33137104
• PMID:7706287
• PMID:9892665

Genes:

• alp4 (SPBC365.15)
• alp7 (SPAC890.02c)
• gfh1 (SPBC211.06)
• mod21 (SPAC806.08c)
• moe1 (SPAC637.07)
• pfd1 (SPBC1D7.01)
• pfd3 (SPAC3H8.07c)
• rae1 (SPBC16A3.05c)

Genotypes:

• alp4-C(566-784)(1-565 Δaa)[Overexpression]
• alp7-RARA(R122A,R124A aa)
• gfh1delta
• mia1-MutNES4(L461A,I463A,L468A,L470A aa)
• mod21delta
• moe1delta
• pfd1delta
• pfd3delta
• rae1-1(G219E aa)

FYPO:0000901 - abnormal microtubule dynamics during vegetative growth

References:

• PMID:15062095

Genes:

• mal3 (SPAC18G6.15)

Genotypes:

• mal3-GFP

FYPO:0004614 - abnormal microtubule polymerization during vegetative growth

References:

• PMID:26124291

Genes:

• alp14 (SPCC895.07)

Genotypes:

• alp14delta

FYPO:0005045 - abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation

References:

• PMID:19948483

Genes:

• rad21 (SPCC338.17c)

Genotypes:

• rad21-K1(unknown)

FYPO:0005046 - abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation

References:

• PMID:11069763
• PMID:12773392

Genes:

• alp13 (SPAC23H4.12)
• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)

Genotypes:

• alp13delta
• chp1delta
• csp10-439(unknown)

FYPO:0000338 - abnormal mitotic spindle

References:

• PMID:12065422
• PMID:15797925
• PMID:17442892
• PMID:1770000
• PMID:19606211
• PMID:22042620
• PMID:22134091
• PMID:23576550
• PMID:24963130
• PMID:25103238
• PMID:6094012
• PMID:7744248
• PMID:8537450
• PMID:9264467

Genes:

• aat1 (SPBC359.03c)
• alp41 (SPAC22F3.05c)
• alp7 (SPAC890.02c)
• apq12 (SPBC428.04)
• cam1 (SPAC3A12.14)
• cut11 (SPAC1786.03)
• fin1 (SPAC19E9.02)
• gtb1 (SPBC32F12.04)
• mal3 (SPAC18G6.15)
• nda3 (SPBC26H8.07c)
• plo1 (SPAC23C11.16)
• pol1 (SPAC3H5.06c)
• prp17 (SPBC6B1.10)
• spc7 (SPCC1020.02)

Genotypes:

• aat1+(wild type)[Overexpression]
• alp41-5(L36Q aa)
• apq12delta
• cam1-E14(E69V,E106V aa)
• cut11-6(T498I aa)
• fin1-A5(Y84N aa)
• fin1-ts1(G188E aa)
• gtb1+(wild type)[Knockdown]
• mal3-Q89R(aa)
• mia1-MutNES4(L461A,I463A,L468A,L470A aa)
• nda3-KM311(G93E aa)
• plo1+(wild type)[Overexpression]
• plo1-24c(unknown)
• pol1delta
• prp17+(wild type)[Overexpression]
• spc7-23(T3887G,G4079T nt)

FYPO:0000177 - abnormal mitotic spindle assembly

References:

• PMID:14742702
• PMID:16611237
• PMID:17476213
• PMID:1855255
• PMID:24937146
• PMID:25103238
• PMID:32441227
• PMID:33125111
• PMID:3409871
• PMID:38442865
• PMID:9078390
• PMID:9892665

Genes:

• alp4 (SPBC365.15)
• alp7 (SPAC890.02c)
• dis1 (SPCC736.14)
• fzo1 (SPBC1706.03)
• mal3 (SPAC18G6.15)
• moe1 (SPAC637.07)
• mor2 (SPBP19A11.04c)
• pim1 (SPBC557.03c)
• tts1 (SPBC1539.04)

Genotypes:

• NLS-alp4-C(566-784)(NLS-alp4(566-784))[Overexpression]
• alp7-5A-b(K341A,Y344A,R346A,K347A,Y348A aa)
• alp7-738(unknown)
• dis1+(wild type)[Overexpression]
• dis1-288(unknown)
• fzo1delta
• mal3+(wild type)[Overexpression]
• moe1delta
• mor2-786(A1673G nt)
• pim1-46(unknown)
• pim1-F201S(aa)
• tts1delta

FYPO:0000131 - abnormal mitotic spindle elongation

References:

• PMID:11432827
• PMID:11861551
• PMID:16611237
• PMID:21920317
• PMID:8065367

Genes:

• alp14 (SPCC895.07)
• alp4 (SPBC365.15)
• bir1 (SPCC962.02c)
• cut8 (SPAC17C9.13c)
• rec12 (SPAC17A5.11)

Genotypes:

• NLS-alp4-C(566-784)(NLS-alp4(566-784))[Overexpression]
• alp14-1270(unknown)
• bir1+(wild type)[Knockdown]
• cut8-563(S201P aa)
• rec12delta

FYPO:0003304 - abnormal mitotic spindle midzone assembly

References:

• PMID:25375240
• PMID:9348288

Genes:

• mal3 (SPAC18G6.15)
• mis19 (SPBC27B12.02)

Genotypes:

• kis1-1(R65C aa)
• mal3+(wild type)[Overexpression]

FYPO:0001791 - abnormal mitotic spindle pole body duplication

References:

• PMID:28242692
• PMID:28619713

Genes:

• sad1 (SPBC12D12.01)
• vps4 (SPAC2G11.06)

Genotypes:

• sad1.1(A323V aa)
• vps4delta

FYPO:0006387 - abnormal mitotic spindle pole body organization

References:

• PMID:34133218

Genes:

• csi1 (SPBC2G2.14)
• plo1 (SPAC23C11.16)

Genotypes:

• csi1delta
• plo1-24c(unknown)
• plo1-as8(C55V,L117G,M170F aa)

FYPO:0001733 - abnormal mitotic spindle pole body separation

References:

• PMID:10521402
• PMID:14742702
• PMID:17036054
• PMID:17486116
• PMID:28242692

Genes:

• alp7 (SPAC890.02c)
• msd1 (SPBC13E7.06)
• nda3 (SPBC26H8.07c)
• rad3 (SPBC216.05)
• vps4 (SPAC2G11.06)

Genotypes:

• alp7+(wild type)[Overexpression]
• msd1delta
• nda3-KM311(G93E aa)
• rad3-136(unknown)[Null]/rad3-136(unknown)[Null]
• vps4delta

FYPO:0004316 - abnormal post-anaphase array

References:

• PMID:36980258

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0004317 - abnormal post-anaphase array morphology

References:

• PMID:11432827
• PMID:16481403

Genes:

• alp14 (SPCC895.07)
• alp7 (SPAC890.02c)

Genotypes:

• alp14-1270(unknown)
• alp7delta

FYPO:0004625 - abnormal post-anaphase microtubule array organization

References:

• PMID:15004232

Genes:

• gfh1 (SPBC211.06)

Genotypes:

• gfh1delta

FYPO:0003561 - abnormal prospore-specific spindle pole body remodeling

References:

• PMID:16896214
• PMID:18411246

Genes:

• mug27 (SPCC417.06c)
• spo5 (SPBC29A10.02)

Genotypes:

• mug27delta
• spo5delta

FYPO:0007745 - abnormal spindle assembly during meiosis I

References:

• PMID:12606573
• PMID:32723864

Genes:

• dhc1 (SPAC1093.06c)
• rec7 (SPCC1753.03c)

Genotypes:

• dhc1delta/dhc1delta
• rec7-146(unknown)/rec7-146(unknown)

FYPO:0003607 - abnormal spindle morphology

References:

• PMID:8898367

Genes:

• cut7 (SPAC25G10.07c)

Genotypes:

• cut7-446(I954T aa)

FYPO:0005652 - abnormal spindle morphology during meiosis I

References:

• PMID:21084840

Genes:

• rdh54 (SPAC22F3.03c)

Genotypes:

• rdh54-70%-deleted

FYPO:0006022 - abnormal spindle pole body morphology during meiosis I

References:

• PMID:15992541

Genes:

• dot2 (SPBC651.05c)

Genotypes:

• dot2-439(E33*)/dot2-439(E33*)

FYPO:0004608 - abnormal spindle pole body morphology during meiosis II

References:

• PMID:10639340
• PMID:15569158
• PMID:15992541
• PMID:20833892
• PMID:8203159

Genes:

• cam1 (SPAC3A12.14)
• dot2 (SPBC651.05c)
• spo15 (SPAC1F3.06c)
• spo20 (SPAC3H8.10)
• spo4 (SPBC21C3.18)

Genotypes:

• cam1-22,117(D22Y,R117F aa)
• dot2-439(E33*)/dot2-439(E33*)
• spo15::ura4+
• spo20-H6(T170I aa)
• spo4-B4(unknown)

FYPO:0004584 - abnormally arrested meiosis I with four spindle pole bodies

References:

• PMID:9763441

Genes:

• top2 (SPBC1A4.03c)

Genotypes:

• top2-191(unknown)

FYPO:0004623 - abolished astral microtubule anchoring at mitotic spindle pole body

References:

• PMID:11676915
• PMID:15004232

Genes:

• cdc11 (SPCC1739.11c)
• gfh1 (SPBC211.06)

Genotypes:

• cdc11delta
• gfh1delta

FYPO:0005695 - abolished astral microtubule nucleation during mitosis

References:

• PMID:37783794

Genes:

• pcp1 (SPAC6G9.06c)

Genotypes:

• pcp1-AID(pcp1::pcp1-XTEN16-3×sAID:kanMX6)[Knockdown]

FYPO:0004766 - abolished cytoplasmic interphase microtubule nucleation

References:

• PMID:15004232
• PMID:15772152
• PMID:15800064

Genes:

• mto1 (SPCC417.07c)
• mto2 (SPBC902.06)

Genotypes:

• mto1delta
• mto2delta

FYPO:0005697 - abolished cytoplasmic interphase microtubule nucleation from spindle pole body

References:

• PMID:19001497

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1-9A1(DNLRKEVFG259AAAAAAAAA aa)
• mto1-9A2(GLKLKCYFL267AAAAAAAAA aa)
• mto1delta

FYPO:0004616 - abolished cytoplasmic microtubule depolymerization at plus end at cell tip

References:

• PMID:15772152

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0005696 - abolished cytoplasmic microtubule nucleation from iMTOC

References:

• PMID:19001497

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1-334(523-537 Δaa)
• mto1-9A1(DNLRKEVFG259AAAAAAAAA aa)
• mto1-9A2(GLKLKCYFL267AAAAAAAAA aa)
• mto1delta

FYPO:0004624 - abolished eMTOC assembly

References:

• PMID:15068790
• PMID:15800064

Genes:

• mto2 (SPBC902.06)
• rsp1 (SPBC11B10.05c)

Genotypes:

• mto2delta
• rsp1+(wild type)[Overexpression]

FYPO:0007984 - abolished eMTOC disassembly

References:

• PMID:15068790

Genes:

• rsp1 (SPBC11B10.05c)

Genotypes:

• rsp1-1(P41L aa)
• rsp1delta

FYPO:0007081 - abolished initial meiotic spindle pole body separation in meiosis I

References:

• PMID:27889481

Genes:

• bqt1 (SPAC6G9.13c)

Genotypes:

• bqt1delta

FYPO:0007485 - abolished meiotic spindle microtubule nucleation from new spindle pole body during meiosis II

References:

• PMID:27889481

Genes:

• bqt1 (SPAC6G9.13c)

Genotypes:

• bqt1delta

FYPO:0005988 - abolished microtubule anchoring at cell cortex of cell tip during meiotic cell cycle

References:

• PMID:25736293

Genes:

• arp1 (SPBC1347.12)
• ssm4 (SPAC27D7.13c)

Genotypes:

• arp1delta
• ssm4-dC540(541-670 Δaa)

FYPO:0006343 - abolished microtubule bundle formation

References:

• PMID:19430466

Genes:

• klp2 (SPAC664.10)

Genotypes:

• klp2-motor(1-355 Δaa)
• klp2-tail(634-817 Δaa)

FYPO:0006067 - abolished microtubule polymerization

References:

• PMID:22696680

Genes:

• alp14 (SPCC895.07)

Genotypes:

• alp14-TOG1,2(W23A,R109A,W300A,K381A aa)

FYPO:0001683 - abolished mitotic spindle assembly

References:

• PMID:12815070
• PMID:18362178
• PMID:19074598
• PMID:27889481
• PMID:3040264
• PMID:9348288

Genes:

• mal3 (SPAC18G6.15)
• nda3 (SPBC26H8.07c)
• plo1 (SPAC23C11.16)
• sad1 (SPBC12D12.01)
• tbf1 (SPBC19G7.13)

Genotypes:

• mal3+(wild type)[Overexpression]
• nda3-KM311(G93E aa)
• plo1-ts2(E139K aa)
• sad1.2(T3S,S52P aa)
• tbf1delta

FYPO:0004622 - abolished mitotic spindle disassembly

References:

• PMID:15772152
• PMID:31276301
• PMID:32502403

Genes:

• apq12 (SPBC428.04)
• imp1 (SPBC1604.08c)
• klp8 (SPAC144.14)
• mto1 (SPCC417.07c)

Genotypes:

• apq12delta
• imp1delta
• klp8+(wild type)[Overexpression]
• mto1delta

FYPO:0003829 - abolished mitotic spindle elongation

References:

• PMID:11448769
• PMID:18362178

Genes:

• acr1 (SPBC17D1.04)
• clp1 (SPAC1782.09c)

Genotypes:

• acr1-936(unknown)
• clp1+(wild type)[Overexpression]

FYPO:0006174 - abolished mitotic spindle elongation during anaphase B

References:

• PMID:10398680
• PMID:10468581
• PMID:11882285
• PMID:25375240
• PMID:31615768

Genes:

• bir1 (SPCC962.02c)
• mis4 (SPAC31A2.05c)
• mis6 (SPAC1687.20c)
• peg1 (SPAC3G9.12)

Genotypes:

• bir1delta
• cls1-28(L797P aa)
• mis4-242(G1326E aa)
• mis6-302(G135E aa)

FYPO:0006173 - abolished mitotic spindle elongation during prophase

References:

• PMID:14742702
• PMID:19942852
• PMID:25987607

Genes:

• alp7 (SPAC890.02c)
• cut7 (SPAC25G10.07c)
• pcp1 (SPAC6G9.06c)

Genotypes:

• alp7-738(unknown)
• cut7-21(M394T aa)
• pcp1-15(I172T,K543E,I624T,E732G,A1022V,I1153V,H1163R aa)
• pcp1-18(L254S,L717P aa)

FYPO:0005344 - abolished mitotic spindle midzone assembly

References:

• PMID:19686686
• PMID:23986474

Genes:

• cut7 (SPAC25G10.07c)

Genotypes:

• cut7-24(V968A aa)

FYPO:0001792 - abolished mitotic spindle pole body duplication

References:

• PMID:12376568
• PMID:2211869
• PMID:9763447

Genes:

• cut11 (SPAC1786.03)
• nda3 (SPBC26H8.07c)
• ned1 (SPAC1952.13)

Genotypes:

• cut11-2(C525R aa)
• nda3-KM311(G93E aa)
• ned1+(wild type)[Overexpression]

FYPO:0001734 - abolished mitotic spindle pole body separation

References:

• PMID:11432827
• PMID:17579515
• PMID:20967237
• PMID:7744248

Genes:

• alp14 (SPCC895.07)
• alp7 (SPAC890.02c)
• cdc11 (SPCC1739.11c)
• plo1 (SPAC23C11.16)

Genotypes:

• alp14-1270(unknown)
• alp7+(wild type)[Overexpression]
• cdc11-119(unknown)
• plo1+(wild type)[Overexpression]

FYPO:0003542 - abolished protein localization to meiotic spindle pole body

References:

• PMID:16615890
• PMID:18550796
• PMID:20298435
• PMID:20833892
• PMID:21775631
• PMID:24838944
• PMID:27630265

Genes:

• bqt1 (SPAC6G9.13c)
• byr4 (SPAC222.10c)
• cam1 (SPAC3A12.14)
• cdc16 (SPAC6F6.08c)
• dhc1 (SPAC1093.06c)
• spo13 (SPCC1183.12)
• spo15 (SPAC1F3.06c)
• spo7 (SPAC6G9.04)

Genotypes:

• bqt1delta
• byr4delta
• cam1-22,117(D22Y,R117F aa)
• cdc16delta
• dhc1delta
• spo13delta
• spo15delta
• spo7delta

FYPO:0007246 - abolished protein localization to meiotic spindle pole body during anaphase II

References:

• PMID:16787941
• PMID:20980623
• PMID:24838944

Genes:

• cdc11 (SPCC1739.11c)
• cdc7 (SPBC21.06c)
• spg1 (SPAC1565.06c)

Genotypes:

• cdc11-123(R947H,T1041I aa)
• cdc11-136(N767M aa)/cdc11-136(N767M aa)
• cdc7+(wild type)[Ectopic]/cdc7+(wild type)[Ectopic]
• spg1+(wild type)[Ectopic]/spg1+(wild type)[Ectopic]

FYPO:0007999 - abolished protein localization to spindle pole body during karyogamy

References:

• PMID:25869666

Genes:

• dli1 (SPAC458.04c)

Genotypes:

• dli1delta

FYPO:0004830 - arrested mitotic spindle elongation during anaphase B

References:

• PMID:11554922
• PMID:9802907

Genes:

• bir1 (SPCC962.02c)
• cut1 (SPCC5E4.04)

Genotypes:

• cut1-206(L739C aa)
• cut17-275(A990T aa)

FYPO:0004618 - astral microtubules absent from cell

References:

• PMID:15772152

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0004732 - astral microtubules present in decreased numbers

References:

• PMID:15772152

Genes:

• alp4 (SPBC365.15)

Genotypes:

• alp4-1891(unknown)

FYPO:0001978 - bent mitotic spindle

References:

• PMID:11102508
• PMID:11864908
• PMID:12719471
• PMID:14742702
• PMID:1538784
• PMID:16920624
• PMID:17442892
• PMID:22292001
• PMID:23267073
• PMID:37288768
• PMID:9531532
• PMID:9763447

Genes:

• alp7 (SPAC890.02c)
• cbf11 (SPCC736.08)
• cdc20 (SPBC25H2.13c)
• cut11 (SPAC1786.03)
• cut12 (SPBC649.05)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• fbh1 (SPBC336.01)
• moe1 (SPAC637.07)
• pcp1 (SPAC6G9.06c)
• raf1 (SPCC613.12c)
• raf2 (SPCC970.07c)
• sim3 (SPBC577.15c)
• skp1 (SPBC409.05)
• spc7 (SPCC1020.02)

Genotypes:

• alp7+(wild type)[Overexpression]
• cbf11delta
• cdc20-P7(unknown)
• cut11-2(C525R aa)
• cut12+(wild type)[Overexpression]
• cut7-ts(unknown)
• dis1-6E(T279E,S293E,S300E,S551E,S556E,S590E aa)
• fbh1delta
• moe1delta
• pcp1+(wild type)[Overexpression]
• raf1delta
• raf2delta
• sim3-143(G81E aa)
• skp1-A7(I110T aa)
• spc7-23(T3887G,G4079T nt)

FYPO:0007101 - bent spindle during meiosis I

References:

• PMID:22292001

Genes:

• fbh1 (SPBC336.01)
• skp1 (SPBC409.05)

Genotypes:

• fbh1-D485N(aa)
• fbh1-P15A,L26A(aa)
• fbh1delta
• skp1-A7(I110T aa)

FYPO:0006346 - bipolar mitotic spindle with decreased, irregular thickness

References:

• PMID:12951601

Genes:

• alp7 (SPAC890.02c)

Genotypes:

• alp7delta

FYPO:0003327 - curved interphase microtubules

References:

• PMID:11080156
• PMID:12427731
• PMID:15797925
• PMID:16096637
• PMID:16325501
• PMID:24530531
• PMID:25210736
• PMID:29316864
• PMID:33925026

Genes:

• alp6 (SPBC428.20c)
• amo1 (SPBC15D4.10c)
• klp6 (SPBC1685.15c)
• mcp1 (SPAC1687.10)
• mor2 (SPBP19A11.04c)
• mto1 (SPCC417.07c)
• mto2 (SPBC902.06)
• nak1 (SPBC17F3.02)
• pmo25 (SPAC1834.06c)
• rst2 (SPAC6F12.02)
• tea4 (SPBC1706.01)

Genotypes:

• alp6-719(unknown)
• amo1delta
• klp6delta
• mcp1delta
• mor2-786(A1673G nt)
• mto1delta
• mto2delta
• nak1+(wild type)[Knockdown]
• nak1-125(T198I aa)
• pmo25-2(F184C,F206V aa)
• pmo25-35(L79H aa)
• rst2+(wild type)[Overexpression]
• rst2-C2H2delta(70-97 Δaa)[Overexpression]
• tea4delta

FYPO:0004862 - curved microtubules

References:

• PMID:15797925

Genes:

• aat1 (SPBC359.03c)
• cop1 (SPBPJ4664.04)
• gbs1 (SPCC825.02)
• isp3 (SPAC1F8.05)
• kgd1 (SPBC3H7.03c)
• mas5 (SPBC1734.11)
• mcp1 (SPAC1687.10)
• nup45 (SPAC22G7.09c)
• slt1 (SPAC17G6.13)
• vps52 (SPBC336.11)
• SPBC16E9.02c
• SPBC543.02c

Genotypes:

• SPBC16E9.02c+(wild type)[Overexpression]
• SPBC543.02c+(wild type)[Overexpression]
• aat1+(wild type)[Overexpression]
• cop1+(wild type)[Overexpression]
• gbs1+(wild type)[Overexpression]
• isp3+(wild type)[Overexpression]
• kgd1+(wild type)[Overexpression]
• mas5delta
• mcp1delta
• nup45+(wild type)[Overexpression]
• slt1+(wild type)[Overexpression]
• vps52+(wild type)[Overexpression]

FYPO:0005721 - curved mitotic spindle during anaphase B

References:

• PMID:11972773
• PMID:15147872
• PMID:36695178

Genes:

• ptp4 (SPBC3D6.05)
• shk1 (SPBC1604.14c)
• skp1 (SPBC409.05)

Genotypes:

• orb2-34(unknown)
• ptp4delta
• shk1-K415R(aa)
• skp1-A7(I110T aa)

FYPO:0004728 - cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough

References:

• PMID:15772152

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0004702 - cytoplasmic microtubules absent from cell

References:

• PMID:15797925
• PMID:9450991
• PMID:9658169

Genes:

• alp1 (SPBC11C11.04c)
• alp11 (SPAC13D6.05)
• atb2 (SPBC800.05c)
• fin1 (SPAC19E9.02)
• nda3 (SPBC26H8.07c)
• prp17 (SPBC6B1.10)

Genotypes:

• alp1-1315(unknown)
• alp11-924(W119*)
• alp12-1828(T1566C nt)
• alp2-996(G1067A nt)
• atb2-1212(G737A nt)
• fin1+(wild type)[Overexpression]
• prp17+(wild type)[Overexpression]

FYPO:0006397 - cytoplasmic microtubules detached from nuclear envelope

References:

• PMID:16481403

Genes:

• alp7 (SPAC890.02c)

Genotypes:

• alp7delta

FYPO:0004619 - cytoplasmic microtubules nucleated from eMTOC absent from cell

References:

• PMID:15772152
• PMID:19001497

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1-9A1(DNLRKEVFG259AAAAAAAAA aa)
• mto1-9A2(GLKLKCYFL267AAAAAAAAA aa)
• mto1delta

FYPO:0004733 - cytoplasmic microtubules nucleated from eMTOC present in decreased numbers

References:

• PMID:15772152

Genes:

• alp4 (SPBC365.15)

Genotypes:

• alp4-1891(unknown)

FYPO:0007182 - decreased cytoplasmic microtubule depolymerization at plus end at cell tip

References:

• PMID:31276301
• PMID:39509469

Genes:

• klp8 (SPAC144.14)
• rgf1 (SPCC645.07)

Genotypes:

• klp8+(wild type)[Overexpression]
• rgf1delta

FYPO:0009001 - decreased duration of cytoplasmic microtubule growth events during mitotic interphase

References:

• PMID:24928430
• PMID:36633091

Genes:

• mal3 (SPAC18G6.15)
• tea2 (SPBC1604.20c)

Genotypes:

• mal3delta
• tea2delta

FYPO:0005694 - decreased interphase microtubule nucleation

References:

• PMID:19001497
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• mto1 (SPCC417.07c)

Genotypes:

• alp14-26(C450R aa)
• mto1-9A2(GLKLKCYFL267AAAAAAAAA aa)

FYPO:0009056 - decreased kinetochore microtubule depolymerization during mitotic anaphase A

References:

• PMID:36435910

Genes:

• dis1 (SPCC736.14)

Genotypes:

• alp14TOG-dis1C(alp14(1-500)-dis1(518-882))
• dis1delta

FYPO:0005363 - decreased kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture

References:

• PMID:18256284

Genes:

• klp2 (SPAC664.10)

Genotypes:

• klp2delta

FYPO:0007150 - decreased microtubule bundle formation

References:

• PMID:21151990

Genes:

• ase1 (SPAPB1A10.09)
• klp2 (SPAC664.10)

Genotypes:

• ase1delta
• klp2delta

FYPO:0007706 - decreased microtubule depolymerization at cell side

References:

• PMID:26443240

Genes:

• pka1 (SPBC106.10)

Genotypes:

• pka1delta

FYPO:0005682 - decreased microtubule depolymerization during vegetative growth

References:

• PMID:12426374
• PMID:22696680
• PMID:25254656
• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• asp1 (SPCC1672.06c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta
• asp1-H397A(aa)
• klp5delta
• klp6delta
• nda3-TB101(Y50S aa)

FYPO:0005799 - decreased microtubule dwell time at cell tip

References:

• PMID:11007487
• PMID:25254656

Genes:

• asp1 (SPCC1672.06c)
• tip1 (SPAC3C7.12)

Genotypes:

• asp1-D333A(aa)
• tip1delta

FYPO:0005681 - decreased microtubule polymerization

References:

• PMID:22134091
• PMID:22696680
• PMID:31618856
• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• klp6 (SPBC1685.15c)
• mal3 (SPAC18G6.15)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14-26(C450R aa)
• alp14delta
• klp6delta
• mal3-S147A,S151A(aa)
• mal3-S147E,S151E(aa)
• mal3-S147E(aa)
• nda3-TB101(Y50S aa)

FYPO:0000904 - decreased microtubule polymerization or depolymerization

References:

• PMID:16394105
• PMID:18061564
• PMID:20624975
• PMID:24530531

Genes:

• ask1 (SPBC27.02c)
• atb2 (SPBC800.05c)
• mcp1 (SPAC1687.10)
• peg1 (SPAC3G9.12)

Genotypes:

• ask1delta
• atb2-983(V260I aa)
• cls1-36(unknown)
• mcp1delta

FYPO:0006336 - decreased mitotic microtubule nucleation

References:

• PMID:27053664
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• alp16 (SPCC4G3.19)
• gfh1 (SPBC211.06)
• mod21 (SPAC806.08c)

Genotypes:

• alp14-26(C450R aa)
• alp16delta
• gfh1delta
• mod21delta

FYPO:0004650 - decreased mitotic spindle microtubule depolymerization

References:

• PMID:25253718

Genes:

• csi2 (SPAC4D7.07c)

Genotypes:

• csi2delta

FYPO:0005423 - decreased mitotic spindle microtubule depolymerization during mitotic anaphase A

References:

• PMID:20624975

Genes:

• ask1 (SPBC27.02c)
• dam1 (SPAC589.08c)

Genotypes:

• ask1delta
• dam1delta

FYPO:0006593 - decreased mitotic spindle microtubule nucleation from spindle pole body

References:

• PMID:19942852

Genes:

• pcp1 (SPAC6G9.06c)

Genotypes:

• pcp1-15(I172T,K543E,I624T,E732G,A1022V,I1153V,H1163R aa)
• pcp1-18(L254S,L717P aa)

FYPO:0006195 - decreased number of elongated microtubule bundles curved around cell end

References:

• PMID:10749926
• PMID:14742702
• PMID:16481403

Genes:

• alp7 (SPAC890.02c)
• gtb1 (SPBC32F12.04)

Genotypes:

• alp7+(wild type)[Overexpression]
• alp7delta
• gtb1-93(P302L aa)

FYPO:0006885 - decreased protein level at mitotic spindle

References:

• PMID:30463883

Genes:

• alp16 (SPCC4G3.19)
• mal3 (SPAC18G6.15)

Genotypes:

• alp16delta
• mal3delta

FYPO:0002772 - decreased protein localization to meiotic spindle pole body

References:

• PMID:16303567
• PMID:22438582
• PMID:27630265
• PMID:27889481

Genes:

• bqt2 (SPAC1002.06c)
• cdc2 (SPBC11B10.09)
• sad1 (SPBC12D12.01)
• spo13 (SPCC1183.12)
• ypt3 (SPAC18G6.03)

Genotypes:

• bqt2delta
• cdc2-asM17(K79E,F84G aa)[Knockdown]
• sad1.1(A323V aa)
• spo13delta
• ypt3-ki8(A74V aa)

FYPO:0007482 - decreased protein localization to meiotic spindle pole body during meiosis I

References:

• PMID:27889481

Genes:

• bqt1 (SPAC6G9.13c)

Genotypes:

• bqt1delta

FYPO:0006317 - decreased protein localization to meiotic spindle pole body during meiosis II

References:

• PMID:18411246
• PMID:18562696
• PMID:29259000

Genes:

• cdc11 (SPCC1739.11c)
• dms1 (SPCC1739.04c)
• sid4 (SPBC244.01c)

Genotypes:

• cdc11-123(R947H,T1041I aa)
• dms1delta/dms1delta
• sid4+(wild type)[Ectopic]
• sid4-SA1(L629P aa)

FYPO:0007502 - decreased protein localization to meiotic spindle pole body during prophase I

References:

• PMID:16111942

Genes:

• mcp6 (SPBC582.06c)

Genotypes:

• mcp6delta

FYPO:0003190 - decreased rate of cytoplasmic microtubule depolymerization during vegetative growth

References:

• PMID:18799626
• PMID:26443240
• PMID:31276301
• PMID:36633091

Genes:

• dnm1 (SPBC12C2.08)
• klp6 (SPBC1685.15c)
• klp8 (SPAC144.14)
• pka1 (SPBC106.10)
• tea2 (SPBC1604.20c)

Genotypes:

• dnm1delta
• klp5N/klp6C(klp5(1-404)-Klp6(411-784))
• klp8+(wild type)[Overexpression]
• pka1delta
• tea2delta

FYPO:0009000 - decreased rate of cytoplasmic microtubule polymerization during mitotic interphase

References:

• PMID:24928430
• PMID:36633091

Genes:

• rqc2 (SPCC132.01c)
• tea2 (SPBC1604.20c)

Genotypes:

• rqc2delta
• tea2delta

FYPO:0007972 - decreased rate of interpolar microtubule polymerization during mitotic anaphase B

References:

• PMID:35293864

Genes:

• mal3 (SPAC18G6.15)
• peg1 (SPAC3G9.12)

Genotypes:

• mal3delta
• peg1+(wild type)[Overexpression]

FYPO:0009057 - decreased rate of microtubule catastrophe involved in meitotic centromere clustering during meiotic prophase I

References:

• PMID:36435910

Genes:

• dis1 (SPCC736.14)
• ndc80 (SPBC11C11.03)

Genotypes:

• alp14TOG-dis1C(alp14(1-500)-dis1(518-882))
• dis1delta
• ndc80-21(T307A,E379G,L405P aa)

FYPO:0004975 - decreased rate of microtubule depolymerization behind moving spindle pole body

References:

• PMID:16611238

Genes:

• alp4 (SPBC365.15)

Genotypes:

• alp4-C(566-784)(1-565 Δaa)[Overexpression]

FYPO:0000903 - decreased rate of microtubule depolymerization during vegetative growth

References:

• PMID:10749926
• PMID:16394105
• PMID:18799626
• PMID:21856157
• PMID:22134091
• PMID:25736293
• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• arp1 (SPBC1347.12)
• atb2 (SPBC800.05c)
• dhc1 (SPAC1093.06c)
• gtb1 (SPBC32F12.04)
• jnm1 (SPCC11E10.03)
• klp6 (SPBC1685.15c)
• mal3 (SPAC18G6.15)
• mmb1 (SPBC25B2.07c)
• mug5 (SPAC14C4.08)

Genotypes:

• alp14delta
• arp1delta
• atb2-983(V260I aa)
• dhc1-P1(K1896T aa)
• gtb1-93(P302L aa)
• jnm1delta
• klp5N/klp6C(klp5(1-404)-Klp6(411-784))
• klp6delta
• mal3-3A(S147A,T149A,S151A aa)
• mal3-Q89R(aa)
• mmb1delta
• mug5delta

FYPO:0007112 - decreased rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I

References:

• PMID:23770679

Genes:

• dam1 (SPAC589.08c)
• dis1 (SPCC736.14)

Genotypes:

• dam1delta
• dis1delta

FYPO:0005703 - decreased rate of microtubule polymerization during vegetative growth

References:

• PMID:16394105
• PMID:33925026

Genes:

• alp14 (SPCC895.07)
• atb2 (SPBC800.05c)

Genotypes:

• alp14delta
• atb2-983(V260I aa)

FYPO:0003268 - decreased rate of mitotic spindle elongation

References:

• PMID:15126629
• PMID:19686686
• PMID:23087209
• PMID:28178520
• PMID:30806623
• PMID:31089172
• PMID:37288768

Genes:

• cbf11 (SPCC736.08)
• clp1 (SPAC1782.09c)
• klp2 (SPAC664.10)
• klp9 (SPBC15D4.01c)
• scn1 (SPATRNAALA.03)
• wee1 (SPCC18B5.03)

Genotypes:

• cbf11delta
• clp1-C286S(aa)
• clp1-off(unknown)
• klp2-2A(S113A,S123A aa)
• klp9-2(K333M aa)
• klp9-G296A(aa)
• klp9delta
• scn1-17(C35T nt)
• wee1-50(G850E aa)

FYPO:0005343 - decreased rate of mitotic spindle elongation during anaphase B

References:

• PMID:14742702
• PMID:19686686
• PMID:25778919
• PMID:28178520
• PMID:28513584
• PMID:30806623
• PMID:31089172
• PMID:34080538
• PMID:9802907

Genes:

• alp7 (SPAC890.02c)
• ark1 (SPCC320.13c)
• ase1 (SPAPB1A10.09)
• clp1 (SPAC1782.09c)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• klp9 (SPBC15D4.01c)
• top2 (SPBC1A4.03c)

Genotypes:

• alp7-738(unknown)
• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• ase1+(wild type)[Overexpression]
• ase1-S640D,S683D,S688D,S693D(aa)
• clp1delta
• cut7-122(M134T,T290K aa)
• dis1delta
• klp9-G296A(aa)
• klp9-S596D,S598D,S605D,S611D(aa)
• klp9-delta133C(500-633 Δaa)
• klp9-delta172C(461-633 Δaa)
• klp9-delta234C(399-633 Δaa)
• klp9-delta92C(541-633 Δaa)
• klp9-deltamotor(1-399 Δaa)
• klp9-md(GKT99AAA aa)
• klp9delta
• top2-191(unknown)

FYPO:0007960 - decreased rate of mitotic spindle elongation during prophase

References:

• PMID:24239120

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0005463 - decreased spatial extent of interphase microtubule polymerization

References:

• PMID:12894167

Genes:

• tea2 (SPBC1604.20c)

Genotypes:

• tea2-G364A(aa)
• tea2-T225N(aa)
• tea2delta

FYPO:0004648 - delayed onset of mitotic spindle assembly

References:

• PMID:25253718
• PMID:8978687

Genes:

• csi1 (SPBC2G2.14)
• csi2 (SPAC4D7.07c)
• dma1 (SPAC17G8.10c)

Genotypes:

• csi1delta
• csi2delta
• dma1+(wild type)[Overexpression]

FYPO:0006559 - delayed onset of mitotic spindle disassembly

References:

• PMID:22573890
• PMID:32848252

Genes:

• cyk3 (SPAC9G1.06c)
• imp1 (SPBC1604.08c)

Genotypes:

• cyk3delta
• imp1delta

FYPO:0002636 - delayed onset of mitotic spindle elongation

References:

• PMID:19523829
• PMID:22065639
• PMID:22134091
• PMID:23087209
• PMID:24963130
• PMID:9852154

Genes:

• csm1 (SPAC11E3.03)
• kms2 (SPBC947.12)
• mal3 (SPAC18G6.15)
• mde4 (SPBC6B1.04)
• nsk1 (SPAC3G9.01)
• plo1 (SPAC23C11.16)
• sid2 (SPAC24B11.11c)

Genotypes:

• csm1delta
• kms2+(wild type)[Knockdown]
• mal3-S147E,S151E(aa)
• mal3-S147E(aa)
• mde4-12A(S147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401A aa)
• mde4delta
• nsk1delta
• plo1-24c(unknown)
• plo1-25(unknown)
• sid2-250(E314K aa)

FYPO:0007428 - delayed onset of mitotic spindle microtubule nucleation from old spindle pole body

References:

• PMID:19487457

Genes:

• cut11 (SPAC1786.03)
• cut12 (SPBC649.05)

Genotypes:

• cut11-1(L521F aa)
• cut12-1(R536*)

FYPO:0003566 - delayed onset of mitotic spindle pole body separation

References:

• PMID:22134091
• PMID:24963130
• PMID:25057016

Genes:

• alp7 (SPAC890.02c)
• csi1 (SPBC2G2.14)
• kms2 (SPBC947.12)
• mal3 (SPAC18G6.15)
• plo1 (SPAC23C11.16)

Genotypes:

• alp7delta
• alp7delta(307-312)(aa)
• csi1-I463N,P464N(aa)
• csi1delta
• kms2+(wild type)[Knockdown]
• mal3-Q89R(aa)
• plo1-24c(unknown)

FYPO:0007257 - delayed onset of protein localization to meiotic spindle pole body during meiosis I

References:

• PMID:22438582

Genes:

• cdc31 (SPCC1682.04)
• plo1 (SPAC23C11.16)

Genotypes:

• cdc31-ts10(unknown)
• plo1-ts2(E139K aa)

FYPO:0008006 - dynamic microtubule minus ends in interphase bundles

References:

• PMID:21444751

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0007985 - early eMTOC assembly

References:

• PMID:15068790

Genes:

• rsp1 (SPBC11B10.05c)

Genotypes:

• rsp1-1(P41L aa)

FYPO:0004866 - enlarged post-anaphase array with increased number of microtubules

References:

• PMID:18418055

Genes:

• gtb1 (SPBC32F12.04)

Genotypes:

• gtb1-K5A(K389A aa)
• gtb1-Q10A(Q394A aa)

FYPO:0006049 - fluctuating mitotic spindle length

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta
• klp6delta

FYPO:0004567 - fragmented spindle during meiosis II

References:

• PMID:10886372

Genes:

• spo6 (SPBC1778.04)

Genotypes:

• spo6delta

FYPO:0008008 - increased duration of cytoplasmic microtubule growth events during mitotic interphase

References:

• PMID:22363481
• PMID:24928430
• PMID:36633091

Genes:

• dnm1 (SPBC12C2.08)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• rqc2 (SPCC132.01c)

Genotypes:

• dnm1delta
• klp5delta
• klp6delta
• rqc2delta

FYPO:0004881 - increased duration of mitotic spindle disassembly

References:

• PMID:25963819

Genes:

• imp1 (SPBC1604.08c)

Genotypes:

• imp1delta

FYPO:0007748 - increased duration of spindle assembly during meiosis I

References:

• PMID:32723864

Genes:

• klp2 (SPAC664.10)

Genotypes:

• klp2delta/klp2delta

FYPO:0006105 - increased microtubule depolymerization at cell side

References:

• PMID:26443240

Genes:

• pka1 (SPBC106.10)

Genotypes:

• pka1+(wild type)[Overexpression]

FYPO:0003417 - increased microtubule dwell time at cell tip

References:

• PMID:15797925
• PMID:24530531
• PMID:25254656
• PMID:31553675

Genes:

• amo1 (SPBC15D4.10c)
• asp1 (SPCC1672.06c)
• mcp1 (SPAC1687.10)
• sds23 (SPBC646.13)

Genotypes:

• amo1delta
• asp1-H397A(aa)
• mcp1delta
• sds23delta

FYPO:0007980 - Increased microtubule overlap length in bundles during mitotic interphase:

References:

• PMID:15837798

Genes:

• mto2 (SPBC902.06)

Genotypes:

• mto2delta

FYPO:0006180 - increased microtubule polymerization

References:

• PMID:10749926
• PMID:12426374
• PMID:22134091

Genes:

• gtb1 (SPBC32F12.04)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mal3 (SPAC18G6.15)

Genotypes:

• gtb1-93(P302L aa)
• klp5delta
• klp6delta
• mal3-Q89R(aa)[Overexpression]

FYPO:0007979 - increased number of microtubules per bundle during mitotic interphase

References:

• PMID:15837798

Genes:

• mto2 (SPBC902.06)

Genotypes:

• mto2delta

FYPO:0006886 - increased protein level at mitotic spindle

References:

• PMID:30463883

Genes:

• cut7 (SPAC25G10.07c)

Genotypes:

• cut7-22(P1021S aa)

FYPO:0007971 - increased rate of interpolar microtubule polymerization during mitotic anaphase B

References:

• PMID:35293864

Genes:

• ase1 (SPAPB1A10.09)
• peg1 (SPAC3G9.12)

Genotypes:

• ase1+(wild type)[Knockdown]
• ase1delta
• peg1+(wild type)[Knockdown]

FYPO:0007974 - increased rate of interpolar microtubule polymerization inside the mitotic nuclear membrane bridge

References:

• PMID:35293864

Genes:

• ase1 (SPAPB1A10.09)
• les1 (SPAC23C4.05c)
• nem1 (SPBC3B8.10c)

Genotypes:

• ase1delta
• les1delta
• nem1delta

FYPO:0004976 - increased rate of microtubule depolymerization ahead of moving spindle pole body

References:

• PMID:16611238

Genes:

• alp4 (SPBC365.15)

Genotypes:

• alp4-C(566-784)(1-565 Δaa)[Overexpression]

FYPO:0003194 - increased rate of microtubule depolymerization during vegetative growth

References:

• PMID:11007487
• PMID:18799626
• PMID:26443240
• PMID:36633091

Genes:

• klp5 (SPBC2F12.13)
• mmb1 (SPBC25B2.07c)
• pka1 (SPBC106.10)
• tip1 (SPAC3C7.12)

Genotypes:

• klp5delta
• mmb1delta
• pka1+(wild type)[Overexpression]
• tip1delta

FYPO:0007958 - increased rate of mitotic spindle elongation

References:

• PMID:30806623

Genes:

• cdc25 (SPAC24H6.05)
• klp9 (SPBC15D4.01c)

Genotypes:

• cdc25-22(C532Y aa)
• klp9+(wild type)[Overexpression]

FYPO:0007071 - increased rate of mitotic spindle elongation during anaphase A

References:

• PMID:31427431

Genes:

• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)

Genotypes:

• dis1delta
• klp5delta

FYPO:0005976 - increased rate of mitotic spindle elongation during anaphase B

References:

• PMID:27697865
• PMID:27872152

Genes:

• asp1 (SPCC1672.06c)
• dis1 (SPCC736.14)

Genotypes:

• asp1-D333A(aa)
• dis1-LAPA(L841A,P844A aa)

FYPO:0007959 - increased rate of mitotic spindle elongation during prophase

References:

• PMID:24239120

Genes:

• klp6 (SPBC1685.15c)

Genotypes:

• klp6delta

FYPO:0006102 - interphase microtubules absent from cell

References:

• PMID:11369198
• PMID:8876193
• PMID:9200612

Genes:

• alp14 (SPCC895.07)
• atb2 (SPBC800.05c)
• dis2 (SPBC776.02c)
• nda3 (SPBC26H8.07c)

Genotypes:

• alp14delta
• ban5-996(unknown)
• dis2-1(unknown)
• nda3-KM311(G93E aa)

FYPO:0003227 - interphase microtubules present during mitosis

References:

• PMID:11389855
• PMID:18799626
• PMID:24790093
• PMID:35286199

Genes:

• alp7 (SPAC890.02c)
• ght5 (SPCC1235.14)
• klp6 (SPBC1685.15c)
• skb15 (SPCC16C4.08c)

Genotypes:

• alp7-5A-a(S50A,S51A,T100A,T116A,T131A aa)
• ght5delta
• klp5N/klp6C(klp5(1-404)-Klp6(411-784))
• skb15+(wild type)[Overexpression]

FYPO:0009102 - interphase microtubules present in decreased numbers

References:

• PMID:36980258

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0004704 - interphase microtubules present in increased numbers

References:

• PMID:11121040

Genes:

• int6 (SPBC646.09c)

Genotypes:

• int6delta

FYPO:0004612 - long astral microtubules

References:

• PMID:10749926

Genes:

• gtb1 (SPBC32F12.04)

Genotypes:

• gtb1-93(P302L aa)

FYPO:0004865 - long astral microtubules during mitotic anaphase A

References:

• PMID:18418055

Genes:

• gtb1 (SPBC32F12.04)

Genotypes:

• gtb1-K5A(K389A aa)
• gtb1-Q10A(Q394A aa)

FYPO:0004511 - long curved interphase microtubules

References:

• PMID:11080156
• PMID:11739790
• PMID:12134075
• PMID:15004232
• PMID:15280226
• PMID:15772152
• PMID:16611237
• PMID:19001497
• PMID:30427751
• PMID:39509469

Genes:

• alp16 (SPCC4G3.19)
• alp4 (SPBC365.15)
• gtb1 (SPBC32F12.04)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mto1 (SPCC417.07c)
• rgf1 (SPCC645.07)
• rsp1 (SPBC11B10.05c)
• tea1 (SPCC1223.06)

Genotypes:

• alp16+(wild type)[Overexpression]
• alp16delta
• alp4-1891(unknown)
• alp4-C(566-784)(1-565 Δaa)[Overexpression]
• gtb1-93(P302L aa)
• klp5delta
• klp6delta
• mto1-9A1(DNLRKEVFG259AAAAAAAAA aa)
• mto1-9A2(GLKLKCYFL267AAAAAAAAA aa)
• mto1delta
• rgf1delta
• rsp1+(wild type)[Overexpression]
• tea1delta

FYPO:0004863 - long curved microtubules

References:

• PMID:11967147

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta
• klp6delta

FYPO:0004439 - long curved mitotic spindle during anaphase

References:

• PMID:10749926
• PMID:11102508
• PMID:11121040
• PMID:17352737
• PMID:22134091
• PMID:25963819

Genes:

• cdc48 (SPAC1565.08)
• dad2 (SPAC1805.07c)
• gtb1 (SPBC32F12.04)
• imp1 (SPBC1604.08c)
• int6 (SPBC646.09c)
• mal3 (SPAC18G6.15)
• moe1 (SPAC637.07)
• pim1 (SPBC557.03c)

Genotypes:

• cdc48-353(G332D aa)
• dad2delta
• gtb1-93(P302L aa)
• imp1delta
• int6delta
• mal3-Q89R(aa)
• moe1delta
• pim1-d1(unknown)

FYPO:0000233 - long cytoplasmic microtubules

References:

• PMID:11080156
• PMID:25373780
• PMID:8887563

Genes:

• alp4 (SPBC365.15)
• alp6 (SPBC428.20c)
• apl4 (SPCP1E11.06)
• cph2 (SPAC2F7.07c)
• cuf1 (SPAC31A2.11c)
• elp3 (SPAC29A4.20)
• elp4 (SPCC11E10.06c)
• elp6 (SPBC3H7.10)
• erd1 (SPAC227.01c)
• kti12 (SPAC30.02c)
• med18 (SPAC5D6.05)
• mrp1 (SPNCRNA.82)
• pep3 (SPCC790.02)
• pmt1 (SPBC19C2.02)
• rps1002 (SPBP22H7.08)
• sbh1 (SPBC2G2.03c)
• tsf1 (SPBC800.07c)
• utp502 (SPCC1450.03)
• vps16 (SPAC824.05)
• SPBC17A3.05c

Genotypes:

• SPBC17A3.05cdelta
• alp4+(wild type)[Overexpression]
• alp6+(wild type)[Overexpression]
• apl4delta
• cph2delta
• cuf1delta
• elp3delta
• elp4delta
• elp6delta
• erd1delta
• kti12delta
• med18delta
• mrp1-RR90(199-282 Δnt)
• pep3delta
• pmt1delta
• rps1002delta
• sbh1delta
• tsf1delta
• utp502delta
• vps16delta

FYPO:0004611 - long interphase microtubules

References:

• PMID:11102508
• PMID:12034771
• PMID:15800064

Genes:

• mal3 (SPAC18G6.15)
• mto2 (SPBC902.06)
• tea1 (SPCC1223.06)

Genotypes:

• mal3delta
• mto2delta
• tea1delta

FYPO:0005880 - long interphase microtubules curved around cell end

References:

• PMID:14663827
• PMID:15797925
• PMID:31276301
• PMID:9200612

Genes:

• amo1 (SPBC15D4.10c)
• klp8 (SPAC144.14)
• tea1 (SPCC1223.06)

Genotypes:

• amo1delta
• klp8+(wild type)[Overexpression]
• tea1delta

FYPO:0007847 - long meiosis I spindle

References:

• PMID:34346498

Genes:

• klp5 (SPBC2F12.13)

Genotypes:

• klp5delta

FYPO:0002222 - long meiosis II spindle

References:

• PMID:23370392
• PMID:29259000

Genes:

• dms1 (SPCC1739.04c)
• spo4 (SPBC21C3.18)
• spo5 (SPBC29A10.02)
• spo6 (SPBC1778.04)

Genotypes:

• dms1delta/dms1delta
• spo4-K95A(aa)
• spo4delta
• spo5delta
• spo6delta

FYPO:0000736 - long meiotic spindle

References:

• PMID:26696398

Genes:

• atg7 (SPBC6B1.05c)

Genotypes:

• atg7-m1(W227*)

FYPO:0006044 - long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion

References:

• PMID:27146110

Genes:

• klp6 (SPBC1685.15c)

Genotypes:

• klp6delta

FYPO:0000733 - long mitotic spindle

References:

• PMID:11389855
• PMID:11694582
• PMID:12764130
• PMID:16079915
• PMID:17380189
• PMID:21376595
• PMID:2186047
• PMID:23885124
• PMID:25963819
• PMID:31276301
• PMID:31427431
• PMID:7744953

Genes:

• dam1 (SPAC589.08c)
• dis3 (SPBC26H8.10)
• imp1 (SPBC1604.08c)
• klp2 (SPAC664.10)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• klp8 (SPAC144.14)
• mzt1 (SPAC9G1.15c)
• rng2 (SPAC4F8.13c)
• sad1 (SPBC12D12.01)
• skb15 (SPCC16C4.08c)
• wee1 (SPCC18B5.03)

Genotypes:

• dam1delta
• dis3-54(P509L aa)
• imp1delta
• klp2delta
• klp5-E575P(aa)
• klp5-Q582P(aa)
• klp6-E569P(aa)
• klp6delta
• klp8+(wild type)[Overexpression]
• mzt1-E10P(aa)
• mzt1-T27W(aa)
• rng2-M1(L1092P,H1329L,K1366E aa)
• sad1.1(A323V aa)
• sad1delta
• skb15+(wild type)[Knockdown]
• skb15+(wild type)[Overexpression]
• wee1+(wild type)[Overexpression]

FYPO:0004438 - long mitotic spindle during anaphase

References:

• PMID:27697865

Genes:

• asp1 (SPCC1672.06c)

Genotypes:

• asp1-D333A(aa)

FYPO:0006190 - long mitotic spindle during anaphase A

References:

• PMID:10398680
• PMID:12426374

Genes:

• klp5 (SPBC2F12.13)
• mis12 (SPBC409.04c)
• mis6 (SPAC1687.20c)

Genotypes:

• klp5delta
• mis12-537(G52E aa)
• mis6-302(G135E aa)

FYPO:0004307 - long mitotic spindle during metaphase

References:

• PMID:11882285
• PMID:12242294
• PMID:12719471
• PMID:22264609
• PMID:24239120
• PMID:25253718
• PMID:25472718
• PMID:28455357

Genes:

• alp7 (SPAC890.02c)
• csi2 (SPAC4D7.07c)
• dam1 (SPAC589.08c)
• dcn1 (SPBC839.03c)
• klp2 (SPAC664.10)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mad2 (SPBC20F10.06)
• mal2 (SPAC25B8.14)
• mis4 (SPAC31A2.05c)
• sim4 (SPBC18E5.03c)

Genotypes:

• alp7-LA6(L380A,L387A,L391A,L405A,L418A,L419A aa)
• csi2delta
• dam1delta
• dcn1+(wild type)[Overexpression]
• klp2delta
• klp5delta
• klp6delta
• mad2delta
• mal2-1(E277K aa)
• mis4-242(G1326E aa)
• sim4-193(unknown)

FYPO:0003787 - long mitotic spindle microtubules protruding beyond spindle pole body

References:

• PMID:10398680
• PMID:15004232
• PMID:17486116
• PMID:17579515
• PMID:25987607
• PMID:26031557
• PMID:32327557
• PMID:34864879

Genes:

• alp7 (SPAC890.02c)
• cut7 (SPAC25G10.07c)
• mis12 (SPBC409.04c)
• mis6 (SPAC1687.20c)
• msd1 (SPBC13E7.06)
• mto1 (SPCC417.07c)
• pkl1 (SPAC3A11.14c)
• wdr8 (SPBC32H8.09)

Genotypes:

• alp7+(wild type)[Overexpression]
• cut7+(wild type)[Overexpression]
• mis12-537(G52E aa)
• mis6-302(G135E aa)
• msd1delta
• mto1delta
• pkl1-3xGFP
• pkl1-rigor(G580E)(aa)[Overexpression]
• pkl1delta
• pkl1deltaM(437-832 Δaa)
• wdr8delta

FYPO:0004724 - long nuclear microtubules protruding through nuclear envelope during interphase

References:

• PMID:15772152

Genes:

• mto1 (SPCC417.07c)

Genotypes:

• mto1delta

FYPO:0004021 - long polar microtubules

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta
• klp6delta

FYPO:0000730 - long spindle

References:

• PMID:38166399

Genes:

• wee1 (SPCC18B5.03)

Genotypes:

• wee1delta

FYPO:0007988 - long spindle microtubules protruding beyond spindle pole body during meiosis I

References:

• PMID:32327557

Genes:

• pkl1 (SPAC3A11.14c)

Genotypes:

• pkl1-3xGFP

FYPO:0003614 - meiotic spindle absent from cell during meiosis II

References:

• PMID:14532136
• PMID:34346498

Genes:

• alp14 (SPCC895.07)
• dis1 (SPCC736.14)
• rec8 (SPBC29A10.14)

Genotypes:

• alp14-26(C450R aa)[Knockdown]
• dis1delta
• rec8-RDRD(D369R,D370R,R373E,E379R,E381R,R384E aa)

FYPO:0007983 - microtubule bundles detached from the nuclear envelope

References:

• PMID:15068790

Genes:

• rsp1 (SPBC11B10.05c)

Genotypes:

• rsp1-1(P41L aa)

FYPO:0002818 - microtubule bundles present in decreased numbers

References:

• PMID:10341216
• PMID:15068790
• PMID:15647375
• PMID:15797925
• PMID:19696784
• PMID:19879140
• PMID:22696680
• PMID:23885124
• PMID:33137104
• PMID:38442865

Genes:

• alp14 (SPCC895.07)
• alp21 (SPAC22H10.10)
• alp7 (SPAC890.02c)
• amo1 (SPBC15D4.10c)
• ase1 (SPAPB1A10.09)
• mal3 (SPAC18G6.15)
• mas5 (SPBC1734.11)
• mto1 (SPCC417.07c)
• mto2 (SPBC902.06)
• mzt1 (SPAC9G1.15c)
• pfd1 (SPBC1D7.01)
• pfd3 (SPAC3H8.07c)
• rsp1 (SPBC11B10.05c)

Genotypes:

• alp14delta
• alp21delta
• alp7-L461A(aa)
• amo1delta
• ase1delta
• mal3delta
• mas5delta
• mia1delta151-300(aa)
• mto1delta
• mto2delta
• mzt1-T27W(aa)
• pfd1delta
• pfd3delta
• rsp1+(wild type)[Overexpression]
• rsp1delta

FYPO:0007110 - microtubule bundles present in decreased numbers at spindle pole body during meiosis I

References:

• PMID:23770679

Genes:

• alp14 (SPCC895.07)
• alp7 (SPAC890.02c)

Genotypes:

• alp14delta
• alp7delta

FYPO:0005686 - microtubule bundles present in decreased numbers during mitotic interphase

References:

• PMID:15772152
• PMID:15800064
• PMID:15837798
• PMID:16775007
• PMID:30427751

Genes:

• mto1 (SPCC417.07c)
• mto2 (SPBC902.06)
• ppc89 (SPAC4H3.11c)
• rsp1 (SPBC11B10.05c)

Genotypes:

• mto1delta
• mto2delta
• ppc89+(wild type)[Knockdown]
• rsp1+(wild type)[Overexpression]

FYPO:0002401 - microtubule bundles present in increased numbers

References:

• PMID:11696322
• PMID:15647375
• PMID:15689489
• PMID:23697806
• PMID:25373780
• PMID:33125111
• PMID:38442865

Genes:

• alg6 (SPBC342.01c)
• apl4 (SPCP1E11.06)
• ase1 (SPAPB1A10.09)
• bst1 (SPAC824.02)
• cdt2 (SPAC17H9.19c)
• cph2 (SPAC2F7.07c)
• erd1 (SPAC227.01c)
• for3 (SPCC895.05)
• fzo1 (SPBC1706.03)
• med18 (SPAC5D6.05)
• med20 (SPAC17G8.05)
• meu29 (SPAC25H1.05)
• mor2 (SPBP19A11.04c)
• nak1 (SPBC17F3.02)
• orb6 (SPAC821.12)
• pep3 (SPCC790.02)
• pmo25 (SPAC1834.06c)
• png1 (SPAC3G9.08)
• rxt2 (SPBC428.06c)
• sal3 (SPCC1840.03)
• sbh1 (SPBC2G2.03c)
• sin1 (SPAPYUG7.02c)
• swd1 (SPAC23H3.05c)
• ubr1 (SPBC19C7.02)
• utp502 (SPCC1450.03)
• vps16 (SPAC824.05)
• wat1 (SPBC21B10.05c)
• ypa1 (SPAC4F10.04)
• SPBC17A3.05c

Genotypes:

• SPBC17A3.05cdelta
• alg6delta
• apl4delta
• ase1+(wild type)[Overexpression]
• ase1delta
• bst1delta
• cdt2delta
• cph2delta
• erd1delta
• for3delta
• fzo1delta
• med18delta
• med20delta
• meu29delta
• mor2-786(A1673G nt)
• nak1-125(T198I aa)
• orb6-25(unknown)
• pep3delta
• pmo25-35(L79H aa)
• png1delta
• rxt2delta
• sal3delta
• sbh1delta
• sin1delta
• swd1delta
• ubr1delta
• utp502delta
• vps16delta
• wat1delta
• ypa1delta

FYPO:0008232 - microtubule bundles present in increased numbers during mitotic M phase

References:

• PMID:38442865

Genes:

• mor2 (SPBP19A11.04c)

Genotypes:

• mor2-786(A1673G nt)

FYPO:0002004 - microtubules absent from cell

References:

• PMID:10459013
• PMID:10473641
• PMID:15797925
• PMID:17036054
• PMID:20967237
• PMID:2211869
• PMID:23576550

Genes:

• alp11 (SPAC13D6.05)
• alp41 (SPAC22F3.05c)
• cdc11 (SPCC1739.11c)
• hhp2 (SPAC23C4.12)
• mcp1 (SPAC1687.10)
• mug97 (SPBC146.11c)
• nda3 (SPBC26H8.07c)
• osh2 (SPBC2F12.05c)
• pca1 (SPCC1840.04)
• pcs60 (SPCC1827.03c)
• plt1 (SPBC3B8.04c)
• tbc1 (SPAC328.08c)

Genotypes:

• alp11+(wild type)[Overexpression]
• alp41-5(L36Q aa)
• cdc11-119(unknown)
• hhp2+(wild type)[Overexpression]
• mcp1+(wild type)[Overexpression]
• mug97+(wild type)[Overexpression]
• nda3+(wild type)[Overexpression]
• nda3-KM311(G93E aa)
• osh2+(wild type)[Overexpression]
• pca1+(wild type)[Overexpression]
• pcs60+(wild type)[Overexpression]
• plt1+(wild type)[Overexpression]
• tbc1-11(F174S aa)

FYPO:0001417 - mislocalized eMTOC