Phenotype ontology term - FYPO:0000337 - abnormal mitosis

FYPO:0000337 - abnormal mitosis

References:

• PMID:32848252
• PMID:7774573
• PMID:8631307

Genes:

• cdc2 (SPBC11B10.09)
• imp1 (SPBC1604.08c)
• les1 (SPAC23C4.05c)
• mcm4 (SPCC16A11.17)
• rad1 (SPAC1952.07)

Genotypes:

• cdc2-33(A177T aa) cdc2-DL41(P162L aa)
• cdc2-33(A177T aa) cdc2-DL45(P162S aa)
• cdc21-M68(unknown) rad1-1(unknown)
• imp1delta les1delta

FYPO:0000214 - abnormal mitotic chromosome condensation

References:

• PMID:25520186
• PMID:29735745
• PMID:3040264

Genes:

• cut14 (SPBP4H10.06c)
• cut3 (SPBC146.03c)
• nda3 (SPBC26H8.07c)
• peg1 (SPAC3G9.12)
• top2 (SPBC1A4.03c)
• zas1 (SPBC1198.04c)

Genotypes:

• cut14-G35N(aa)[Overexpression] cut3+(wild type)[Overexpression]
• nda3-KM311(G93E aa) top2-250(cs)(unknown)
• peg1+(wild type) zas1-deltaaj3(834-845 Δaa)

FYPO:0000141 - abnormal mitotic sister chromatid segregation

References:

• PMID:10082519
• PMID:10733588
• PMID:10779336
• PMID:11027263
• PMID:11102508
• PMID:11121040
• PMID:11861765
• PMID:11870212
• PMID:11927555
• PMID:12000964
• PMID:12764130
• PMID:15340008
• PMID:15937127
• PMID:16824200
• PMID:18077559
• PMID:18262494
• PMID:18622392
• PMID:18675827
• PMID:20383139
• PMID:21540296
• PMID:21965289
• PMID:22660415
• PMID:23211746
• PMID:25472718
• PMID:25533348
• PMID:27398807
• PMID:28974540
• PMID:31427431
• PMID:41786187
• PMID:9864354

Genes:

• alm1 (SPAC1486.04c)
• alp7 (SPAC890.02c)
• ams2 (SPCC290.04)
• ast1 (SPCC962.05)
• bub1 (SPCC1322.12c)
• cbh1 (SPAC9E9.10c)
• cbp1 (SPBC1105.04c)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• cig2 (SPAPB2B4.03)
• cnd2 (SPCC306.03c)
• cnp1 (SPBC1105.17)
• cnp3 (SPBC1861.01c)
• crb2 (SPBC342.05)
• cut1 (SPCC5E4.04)
• cut15 (SPCC962.03c)
• cut20 (SPAC19G12.01c)
• dam1 (SPAC589.08c)
• dim1 (SPCC16A11.05c)
• dis1 (SPCC736.14)
• dis2 (SPBC776.02c)
• eso1 (SPBC16A3.11)
• exo1 (SPBC29A10.05)
• fin1 (SPAC19E9.02)
• hhp2 (SPAC23C4.12)
• hsk1 (SPBC776.12c)
• imp1 (SPBC1604.08c)
• int6 (SPBC646.09c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mad2 (SPBC20F10.06)
• mal3 (SPAC18G6.15)
• mis4 (SPAC31A2.05c)
• moe1 (SPAC637.07)
• mph1 (SPBC106.01)
• myh1 (SPAC26A3.02)
• nda3 (SPBC26H8.07c)
• ndc80 (SPBC11C11.03)
• nrm1 (SPBC16A3.07c)
• nsk1 (SPAC3G9.01)
• pab1 (SPAC227.07c)
• pds5 (SPAC110.02)
• rad1 (SPAC1952.07)
• rad2 (SPAC3G6.06c)
• rad3 (SPBC216.05)
• rad60 (SPBC1921.02)
• ras1 (SPAC17H9.09c)
• rec8 (SPBC29A10.14)
• rsc1 (SPBC4B4.03)
• rsc4 (SPBC1734.15)
• sgo1 (SPBP35G2.03c)
• skb15 (SPCC16C4.08c)
• slx8 (SPBC3D6.11c)
• spc7 (SPCC1020.02)
• swi6 (SPAC664.01c)
• tea1 (SPCC1223.06)
• top2 (SPBC1A4.03c)
• top3 (SPBC16G5.12c)
• ulp2 (SPAC17A5.07c)

Genotypes:

• GFP-cnp1 ams2delta
• alm1delta cnp3+(wild type)[Overexpression]
• alp7-LA6(L380A,L387A,L391A,L405A,L418A,L419A aa) mad2delta
• ast1delta exo1+(wild type)[Knockdown] rad2delta
• bub1delta fin1delta
• bub1delta pds5delta
• bub1delta swi6delta
• cbh1delta cbp1::ura4(disruption)
• cds1delta top3-134(unknown)
• chk1-S345A(aa) exo1+(wild type)[Knockdown] rad2delta
• chk1delta exo1+(wild type)[Knockdown] rad2delta
• chk1delta hsk1-1312(S314I aa)
• cig2+(wild type)[Knockdown] nrm1delta
• cig2delta nrm1delta
• cnd2-1(A114T aa) crb2delta
• cnd2-1(A114T aa) rad3delta
• cut1-206(L739C aa) sgo1-N29I(aa)[Ectopic]
• cut1-206(L739C aa) sgo1-T189E(aa)[Ectopic]
• cut15-85(G419S,G450S aa) imp1delta
• dam1-A8-ts(H126R,E149G aa) klp5delta
• dim1-35(G126D aa) lid1-6(unknown)
• dis1delta klp5-Q582P(aa)
• dis2delta nsk1delta
• eso1-G799D(aa) mad2delta
• hhp2delta rec8+(wild type)[Overexpression]
• int6delta ras1delta
• klp5delta klp6delta
• mad2delta nda3-KM311(G93E aa)
• mad2delta ndc80-NH12(F420S aa)
• mal3delta moe1delta
• mis4-242(G1326E aa) pds5delta
• mph1delta spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)
• myh1delta rad1delta
• nda3-KM311(G93E aa) top2-191(unknown)
• pab1-1(I228ITEVI) rad60-4(unknown)
• pab1-1(I228ITEVI) slx8-29(unknown)
• pab1-1(I228ITEVI) ulp2delta
• rad1delta top3-134(unknown)
• rsc1delta rsc4delta
• skb15+(wild type)[Knockdown] tea1delta

FYPO:0005045 - abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation

References:

• PMID:11069763

Genes:

• bub1 (SPCC1322.12c)
• cid12 (SPCC663.12)
• dma1 (SPAC17G8.10c)

Genotypes:

• bub1delta csp10-439(unknown)
• bub1delta csp10-439(unknown) dma1delta

FYPO:0000131 - abnormal mitotic spindle elongation

References:

• PMID:28513584
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• pkl1 (SPAC3A11.14c)

Genotypes:

• alp14-26(C450R aa) dis1delta
• ase1+(wild type)[Knockdown] cut7delta pkl1delta

FYPO:0003844 - abolished mitotic chromosome condensation

References:

• PMID:21540296

Genes:

• cnd2 (SPCC306.03c)

Genotypes:

• cnd2-1(A114T aa) cnd2-3E(S5E,S41E,S52E aa)[Overexpression]

FYPO:0004622 - abolished mitotic spindle disassembly

References:

• PMID:32502403

Genes:

• apq12 (SPBC428.04)
• imp1 (SPBC1604.08c)

Genotypes:

• apq12delta imp1delta

FYPO:0006174 - abolished mitotic spindle elongation during anaphase B

References:

• PMID:28513584

Genes:

• cut7 (SPAC25G10.07c)
• klp9 (SPBC15D4.01c)
• pkl1 (SPAC3A11.14c)

Genotypes:

• cut7delta klp9+(wild type)[Knockdown] pkl1delta

FYPO:0006173 - abolished mitotic spindle elongation during prophase

References:

• PMID:25987607

Genes:

• cut7 (SPAC25G10.07c)
• msd1 (SPBC13E7.06)

Genotypes:

• cut7-21(M394T aa) msd1delta

FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

References:

• PMID:18414064
• PMID:27697865
• PMID:32341083

Genes:

• asp1 (SPCC1672.06c)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• mcm4 (SPCC16A11.17)
• mph1 (SPBC106.01)
• mus81 (SPCC4G3.05c)
• orc5 (SPBC646.14c)
• rad1 (SPAC1952.07)

Genotypes:

• asp1-D333A(aa) mph1delta
• asp1-H397A(aa) mph1delta
• cdc21-M68(unknown) cds1+(wild type)[Overexpression]
• cds1-FHA(S78A,H81A aa) mcm4-tstd(Ub-DHFRts-mcm4)
• cds1delta mcm4-tstd(Ub-DHFRts-mcm4)
• cds1delta mcm4-tstd(Ub-DHFRts-mcm4) mus81delta
• cds1delta mus81delta
• chk1delta orc5-H37(L266P,P375L aa)
• orc5-H37(L266P,P375L aa) rad1delta

FYPO:0000229 - cut

References:

• PMID:10523629
• PMID:10683155
• PMID:10757807
• PMID:11160827
• PMID:11715017
• PMID:12409464
• PMID:14585996
• PMID:15173168
• PMID:15367656
• PMID:15509783
• PMID:20226666
• PMID:31538680
• PMID:32341083
• PMID:38780300
• PMID:39652606
• PMID:8978687
• PMID:9153313
• PMID:9154809
• PMID:9763447
• PMID:9774107
• PMID:9832516
• PMID:9862966
• PMID:9928931

Genes:

• aph1 (SPCC4G3.02)
• bub1 (SPCC1322.12c)
• bub3 (SPAC23H3.08c)
• cbf11 (SPCC736.08)
• cdc1 (SPAC27E2.05)
• cdc10 (SPBC336.12c)
• cdc12 (SPAC1F5.04c)
• cdc17 (SPAC20G8.01)
• cdc18 (SPBC14C8.07c)
• cdc20 (SPBC25H2.13c)
• cdc22 (SPAC1F7.05)
• cdc24 (SPAC8F11.07c)
• cdc25 (SPAC24H6.05)
• cdc27 (SPBC1734.02c)
• cdc6 (SPBC336.04)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• cid1 (SPAC19D5.03)
• crb2 (SPBC342.05)
• cut11 (SPAC1786.03)
• cut12 (SPBC649.05)
• dma1 (SPAC17G8.10c)
• mcm4 (SPCC16A11.17)
• mga2 (SPAC26H5.05)
• mik1 (SPBC660.14)
• mrc1 (SPAC694.06c)
• nda3 (SPBC26H8.07c)
• pcn1 (SPBC16D10.09)
• pfh1 (SPBC887.14c)
• pol1 (SPAC3H5.06c)
• rad1 (SPAC1952.07)
• rad17 (SPAC14C4.13)
• rad26 (SPAC9E9.08)
• rfc2 (SPAC23D3.02)
• spp1 (SPAC6B12.10c)
• ssp2 (SPCC74.03c)
• swi3 (SPBC30D10.04)
• tor1 (SPBC30D10.10c)
• tor2 (SPBC216.07c)

Genotypes:

• aph1delta cds1-myc(C-terminal Myc tagged)
• bub1-delta28-160(aa) nda3-KM311(G93E aa)
• bub3delta nda3-KM311(G93E aa)
• cbf11delta mga2delta
• cbf11delta ssp2delta
• cbf11delta tor1-L2045D(aa)
• cbf11delta tor1delta
• cbf11delta tor2-L2048S(aa)
• cdc1-7(unknown) rad17-d14(R411W aa)
• cdc10-129(T429A aa) crb2-1(C1789T nt)
• cdc10-129(T429A aa) crb2delta
• cdc10-V50(H362Y aa) crb2delta
• cdc12+(wild type) cdc12-deltaC(1437-1841 Δaa)[Overexpression]
• cdc17-K42(E298K aa) chk1delta
• cdc17-K42(E298K aa) crb2delta
• cdc18-K46(unknown) crb2-1(C1789T nt)
• cdc18-K46(unknown) crb2delta
• cdc20-M10(unknown) cds1+(wild type)[Overexpression] rad26.a14(C510CNPLIVC)
• cdc20-M10(unknown) chk1delta
• cdc20-M10(unknown) crb2-1(C1789T nt)
• cdc20-M10(unknown) crb2delta
• cdc20-M10(unknown) rad17-d14(R411W aa)
• cdc20-M10(unknown) rad17delta
• cdc20-M10(unknown) rad26.a14(C510CNPLIVC)
• cdc21-M68(unknown) cds1-D312E(aa)[Overexpression]
• cdc21-M68(unknown) chk1delta
• cdc21-M68(unknown) rad17-d14(R411W aa)
• cdc21-M68(unknown) rad17delta
• cdc22-M45(unknown) chk1delta
• cdc22-M45(unknown) rad17-d14(R411W aa)
• cdc24-M38(R370*) chk1delta
• cdc24-M38(R370*) crb2-1(C1789T nt)
• cdc24-M38(R370*) crb2delta
• cdc25-22(C532Y aa) cdc25-3A(S99A,S192A,S359A aa)[Overexpression]
• cdc25-22(C532Y aa) cdc25-3A(S99A,S192A,S359A aa)[Overexpression] mik1-(unknown)
• cdc25-22(C532Y aa) crb2-1(C1789T nt)
• cdc25-3A(S99A,S192A,S359A aa) mik1-(unknown)
• cdc27-K3(G57R aa) crb2-1(C1789T nt)
• cdc27-K3(G57R aa) crb2delta
• cdc27-P11(G57E aa) cid1delta
• cdc27delta rfc2delta
• cdc6-121(unknown) cid1delta
• cdc6-121(unknown) crb2-1(C1789T nt)
• cdc6-121(unknown) crb2delta
• cdc6-ts1(AP143VS aa) cid1delta
• cdc6-ts1(AP143VS aa) crb2-1(C1789T nt)
• cdc6-ts1(AP143VS aa) crb2delta
• cdc6-ts2(E271K aa) cid1delta
• cdc6-ts2(E271K aa) crb2-1(C1789T nt)
• cdc6-ts2(E271K aa) crb2delta
• cdc6-ts3(R1064Q aa) crb2-1(C1789T nt)
• cdc6-ts3(R1064Q aa) crb2delta
• cds1-rad26(cds1delta::cds1-rad26) chk1delta mrc1delta
• cds1delta chk1delta
• cds1delta chk1delta pcn1-L68S(aa)[Overexpression]
• cds1delta mcm4-tstd(Ub-DHFRts-mcm4)
• chk1delta mrc1-6A(S599A,S604A,S614A,T634A,S637A,T645A aa)
• chk1delta mrc1delta
• chk1delta pol1-ts13(470-472 Δaa)
• chk1delta spp1-14(unknown)
• chk1delta spp1-21(unknown)
• chk1delta spp1-4(unknown)
• chk1delta swi3delta
• crb2-1(C1789T nt) pol1-ts1(unknown)
• crb2delta pcn1-L68S(aa)[Overexpression]
• crb2delta pol1-ts1(unknown)
• cut11-1(L521F aa) cut12-1(R536*)
• cut11-2(C525R aa) cut12-1(R536*)
• dma1::ura4+ nda3-KM311(G93E aa)
• pfh1-R20(T1373C nt) rad1-1(unknown)

FYPO:0001055 - cut following normal mitotic chromosome condensation

References:

• PMID:11084332
• PMID:21540296
• PMID:8632802

Genes:

• cut14 (SPBP4H10.06c)
• cut2 (SPBC14C8.01c)
• cut8 (SPAC17C9.13c)
• cut9 (SPAC6F12.15c)
• dis2 (SPBC776.02c)
• nda3 (SPBC26H8.07c)
• slp1 (SPAC821.08c)

Genotypes:

• cut14-208(S861P aa) nda3-KM311(G93E aa)
• cut2+(wild type) cut2delta80N(1-80 Δaa)[Overexpression]
• cut8-563(S201P aa) cut9-665(A535T aa)
• cut8-563(S201P aa) dis2-11(R245Q aa)
• cut8-563(S201P aa) slp1-362(W376*)

FYPO:0003165 - cut with abnormal chromosome segregation

References:

• PMID:10082519
• PMID:10409743
• PMID:10523629
• PMID:10655214
• PMID:10683155
• PMID:10757751
• PMID:10757807
• PMID:10775265
• PMID:10880469
• PMID:11102508
• PMID:11359920
• PMID:11380623
• PMID:11416129
• PMID:11432827
• PMID:11715016
• PMID:11861765
• PMID:11909965
• PMID:11967147
• PMID:12093738
• PMID:12186947
• PMID:12477395
• PMID:12553909
• PMID:12951601
• PMID:1427071
• PMID:14585996
• PMID:14739927
• PMID:15314153
• PMID:15367656
• PMID:16453724
• PMID:16738311
• PMID:17178839
• PMID:18414064
• PMID:18675827
• PMID:19029336
• PMID:19487457
• PMID:19750219
• PMID:20799962
• PMID:21098121
• PMID:2203537
• PMID:23211746
• PMID:23874188
• PMID:24728197
• PMID:25520186
• PMID:26900649
• PMID:27687771
• PMID:31427431
• PMID:31618856
• PMID:32341083
• PMID:34228709
• PMID:35320724
• PMID:37288768
• PMID:7723827
• PMID:7883794
• PMID:7957061
• PMID:8343962
• PMID:8598285
• PMID:8895665
• PMID:9135148
• PMID:9154809
• PMID:9303312
• PMID:9398669
• PMID:9490640
• PMID:9563836
• PMID:9649516
• PMID:9693370
• PMID:9832516
• PMID:9891039
• PMID:9928931
• PMID:9950674

Genes:

• alp14 (SPCC895.07)
• alp7 (SPAC890.02c)
• apc14 (SPAC27D7.05c)
• apc15 (SPBC83.04)
• ase1 (SPAPB1A10.09)
• ast1 (SPCC962.05)
• atf1 (SPBC29B5.01)
• atg1 (SPCC63.08c)
• bub1 (SPCC1322.12c)
• cbf11 (SPCC736.08)
• cdc1 (SPAC27E2.05)
• cdc10 (SPBC336.12c)
• cdc11 (SPCC1739.11c)
• cdc13 (SPBC582.03)
• cdc16 (SPAC6F6.08c)
• cdc17 (SPAC20G8.01)
• cdc18 (SPBC14C8.07c)
• cdc2 (SPBC11B10.09)
• cdc20 (SPBC25H2.13c)
• cdc22 (SPAC1F7.05)
• cdc24 (SPAC8F11.07c)
• cdc25 (SPAC24H6.05)
• cdc27 (SPBC1734.02c)
• cdc28 (SPBC19C2.01)
• cdc48 (SPAC1565.08)
• cdc6 (SPBC336.04)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• cid1 (SPAC19D5.03)
• cid11 (SPBC1685.06)
• cid12 (SPCC663.12)
• cig1 (SPCC4E9.02)
• cig2 (SPAPB2B4.03)
• crb2 (SPBC342.05)
• csc1 (SPBC3H7.13)
• cut1 (SPCC5E4.04)
• cut12 (SPBC649.05)
• cut14 (SPBP4H10.06c)
• cut2 (SPBC14C8.01c)
• cut20 (SPAC19G12.01c)
• cut3 (SPBC146.03c)
• cut6 (SPAC56E4.04c)
• cut7 (SPAC25G10.07c)
• dfp1 (SPCC550.13)
• dim1 (SPCC16A11.05c)
• dis1 (SPCC736.14)
• dna2 (SPBC16D10.04c)
• exo1 (SPBC29A10.05)
• fin1 (SPAC19E9.02)
• hsk1 (SPBC776.12c)
• hus1 (SPAC20G4.04c)
• int6 (SPBC646.09c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• liz1 (SPBC2G2.01c)
• mad2 (SPBC20F10.06)
• mad3 (SPCC1795.01c)
• mal3 (SPAC18G6.15)
• mcm2 (SPBC4.04c)
• mcm4 (SPCC16A11.17)
• mik1 (SPBC660.14)
• moe1 (SPAC637.07)
• mrc1 (SPAC694.06c)
• mus81 (SPCC4G3.05c)
• myh1 (SPAC26A3.02)
• nda3 (SPBC26H8.07c)
• ndc80 (SPBC11C11.03)
• orc1 (SPBC29A10.15)
• orc2 (SPBC685.09)
• orc5 (SPBC646.14c)
• par1 (SPCC188.02)
• par2 (SPAC6F12.12)
• pcn1 (SPBC16D10.09)
• pds5 (SPAC110.02)
• pim1 (SPBC557.03c)
• pol1 (SPAC3H5.06c)
• pot1 (SPAC26H5.06)
• pyp3 (SPAC11E3.09)
• rad1 (SPAC1952.07)
• rad17 (SPAC14C4.13)
• rad2 (SPAC3G6.06c)
• rad21 (SPCC338.17c)
• rad24 (SPAC8E11.02c)
• rad26 (SPAC9E9.08)
• rad3 (SPBC216.05)
• rad4 (SPAC23C4.18c)
• rad9 (SPAC664.07c)
• rlc1 (SPAC926.03)
• rpt2 (SPBC4.07c)
• rqh1 (SPAC2G11.12)
• rum1 (SPBC32F12.09)
• spb70 (SPCC553.09c)
• spp2 (SPBC17D11.06)
• srw1 (SPAC144.13c)
• swi3 (SPBC30D10.04)
• vht1 (SPAC1B3.16c)
• wee1 (SPCC18B5.03)
• wpl1 (SPBC428.17c)

Genotypes:

• alp14-1270(unknown) mad2delta
• alp14-26(C450R aa) dis1delta
• alp7delta mad2delta
• apc14delta apc15delta
• ase1delta rlc1-SA(S35A,S36A aa)
• ast1delta exo1delta rad2delta
• atf1+(wild type)[Overexpression] cdc25-22(C532Y aa)
• atg1delta cdc48-353(G332D aa)
• bub1delta cbf11delta
• cbf11delta mad2delta
• cbf11delta pds5delta
• cbf11delta wpl1delta
• cdc1-7(unknown) chk1delta
• cdc10-129(T429A aa) chk1delta
• cdc10-129(T429A aa) cut5-T401(unknown)
• cdc10-129(T429A aa) orp1-4(unknown)
• cdc10-129(T429A aa) rad26.a14(C510CNPLIVC)
• cdc10-129(T429A aa) rum1delta
• cdc10-2E(S720E,T723E aa) cds1delta mik1delta
• cdc10-2E(S720E,T723E aa) cds1delta mrc1delta
• cdc10-2E(S720E,T723E aa) mik1delta rad3delta
• cdc10-V50(H362Y aa) cdc13+(wild type)[Knockdown] cig1delta cig2delta
• cdc11-S5A(S121A,S122A,S264A,S345A,S418A aa) cdc16-116(R105C aa) csc1::ura4+[Null]
• cdc17-K42(E298K aa) cdc2-3w(C67Y aa)
• cdc17-K42(E298K aa) chk1-1(E92D aa)
• cdc17-K42(E298K aa) chk1-2(I484T aa)
• cdc17-K42(E298K aa) chk1delta
• cdc17-K42(E298K aa) hus1-14(unknown)
• cdc17-K42(E298K aa) rad1-1(unknown)
• cdc17-K42(E298K aa) rad26.a14(C510CNPLIVC)
• cdc18-K46(unknown) orp1-4(unknown)
• cdc18-K46(unknown) rum1delta
• cdc19-P1(P257L,T272I aa) hsk1-89(L339P,E403K,L416P aa)
• cdc2-1w(G146D aa) orp1-4(unknown)
• cdc2-33(A177T aa) mad2+(wild type)[Overexpression]
• cdc2-3w(C67Y aa) cdc20-M10(unknown)
• cdc2-3w(C67Y aa) cdc24-M38(R370*)
• cdc2-3w(C67Y aa) cdc25delta
• cdc2-3w(C67Y aa) cdc6-ts1(AP143VS aa)
• cdc2-3w(C67Y aa) cdc6-ts2(E271K aa)
• cdc2-3w(C67Y aa) cdc6-ts3(R1064Q aa)
• cdc2-3w(C67Y aa) orp1-4(unknown)
• cdc2-3w(C67Y aa) pol1-ts1(unknown)
• cdc2-3w(C67Y aa) pol1-ts13(470-472 Δaa)
• cdc2-3w(C67Y aa) wee1+(wild type)[Overexpression]
• cdc20-M10(unknown) chk1-1(E92D aa)
• cdc20-M10(unknown) chk1-2(I484T aa)
• cdc20-M10(unknown) chk1delta
• cdc20-M10(unknown) hus1-14(unknown)
• cdc20-M10(unknown) rad1-1(unknown)
• cdc20-P287R(aa) rad3-ts(unknown)
• cdc20-P7(unknown) cid1delta
• cdc20-P7(unknown)/cdc20-P7(unknown) cid12delta/cid12delta
• cdc20-ts-deltaN-term+deltaC-term(1-1140,1282-2199 Δaa) chk1delta
• cdc20-ts(unknown) crb2deltaC(547-778 Δaa)
• cdc21-M68(unknown) cds1+(wild type)[Overexpression]
• cdc21-M68(unknown) orp1-4(unknown)
• cdc21-M68(unknown) rad26.a14(C510CNPLIVC)
• cdc22-M45(unknown) cds1::ura4(disruption)[Null]
• cdc22-M45(unknown) chk1delta
• cdc22-M45(unknown) hsk1-89(L339P,E403K,L416P aa)
• cdc22-M45(unknown) rad26.a14(C510CNPLIVC)
• cdc24-G1(G1301A nt) rad1delta
• cdc24-M38(R370*) chk1-1(E92D aa)
• cdc24-M38(R370*) chk1delta
• cdc24-M38(R370*) hus1-14(unknown)
• cdc24-M38(R370*) rad1-1(unknown)
• cdc24-M38(R370*) rad26.a14(C510CNPLIVC)
• cdc25-22(C532Y aa) cdc25-9A(S99A,S148A,S178A,S192A,S204A,S206A,T226A,S234A,S359A aa)[Overexpression] mik1-(unknown)
• cdc25-d1((-822)-(-7))[Overexpression] cut12-1(R536*)
• cdc27-K3(G57R aa) chk1delta
• cdc27-K3(G57R aa) rad26.a14(C510CNPLIVC)
• cdc27-P11(G57E aa) chk1delta
• cdc27-P11(G57E aa) cid11delta
• cdc27-P11(G57E aa) cid12delta
• cdc27-P11(G57E aa) cid1delta
• cdc27-P11(G57E aa) cid1delta crb2delta
• cdc27-P11(G57E aa) crb2delta
• cdc27-P11(G57E aa)/cdc27-P11(G57E aa) cid12delta/cid12delta
• cdc28-(unknown) cut1-(unknown)
• cdc6-ts(unknown) chk1delta
• cdc6-ts(unknown) crb2deltaC(547-778 Δaa)
• cdc6-ts1(AP143VS aa) chk1-1(E92D aa)
• cdc6-ts1(AP143VS aa) chk1-2(I484T aa)
• cdc6-ts2(E271K aa) chk1-1(E92D aa)
• cdc6-ts2(E271K aa) chk1-2(I484T aa)
• cdc6-ts2(E271K aa) chk1delta
• cdc6-ts3(R1064Q aa) chk1-1(E92D aa)
• cdc6-ts3(R1064Q aa) chk1-2(I484T aa)
• cdc6-ts3(R1064Q aa) chk1delta
• cdc6-ts3(R1064Q aa) rad26delta
• cds1-FHA(S78A,H81A aa) mcm4-tstd(Ub-DHFRts-mcm4)
• cds1::ura4(disruption)[Null] swi7-H4(unknown)
• cds1delta chk1delta
• cds1delta crb2delta
• cds1delta hsk1-89(L339P,E403K,L416P aa)
• cds1delta mcm4-tstd(Ub-DHFRts-mcm4) mus81delta
• cds1delta mus81delta
• cds1delta orc5-H37(L266P,P375L aa)
• cds1delta rad24delta
• chk1-1(E92D aa) pol1-ts1(unknown)
• chk1-2(I484T aa) pol1-ts1(unknown)
• chk1delta exo1delta rad2delta
• chk1delta him1-3A(S183A,T187A,T191A aa)
• chk1delta hsk1-89(L339P,E403K,L416P aa)
• chk1delta mrc1-S604A(aa)
• chk1delta mrc1delta
• chk1delta orc5-H37(L266P,P375L aa)
• chk1delta orp1-4(unknown)
• chk1delta pcn1-3(H44A aa)
• chk1delta pol1-ts1(unknown)
• chk1delta pol1-ts13(470-472 Δaa)
• chk1delta rad24delta
• chk1delta rid2-1(G1541A nt)
• chk1delta swi3delta
• cig2delta mik1delta wee1-50(G850E aa)
• crb2deltaC(547-778 Δaa) swi7-ts(unknown)
• cut1-206(L739C aa) cut2-364(R262*)
• cut1-645(unknown) cut2-364(R262*)
• cut14-208(S861P aa) cut3-477(S1147P aa)
• cut14-G35N(aa)[Overexpression] cut3+(wild type)[Overexpression]
• cut6-promoter-mutant(G(-127)C,G(-125)C,G(-123)A,A(-122)G)[Knockdown] vht1delta
• cut7-446(I954T aa) ndc80-AK01(L246P aa)
• dim1-35(G126D aa) lid1-6(unknown)
• dis1delta klp5-Q582P(aa)
• dna2-C2(L1079S aa) hus1-14(unknown)
• fin1delta pim1-d1(unknown)
• hsk1-89(L339P,E403K,L416P aa) rad3delta
• int6delta mts2-1(unknown)
• klp5+(wild type)[Overexpression] mad2delta
• klp6+(wild type)[Overexpression] mad2delta
• liz1-(unknown) wee1-50(G850E aa)
• mad3delta nda3-KM311(G93E aa)
• mal3delta moe1delta
• mik1delta pyp3+(wild type)[Overexpression]
• myh1delta rad1delta
• nda3-KM311(G93E aa) pds5delta
• orc5-H37(L266P,P375L aa) rad1delta
• orc5-H37(L266P,P375L aa) rad21-K1(unknown)
• orp1-4(unknown) rad1-1(unknown)
• orp1-4(unknown) rad17-W(unknown)
• orp1-4(unknown) rad26delta
• orp1-4(unknown) rad3-136(unknown)
• orp1-4(unknown) wee1-50(G850E aa)
• orp2-2(unknown) rad1-1(unknown)
• orp2-2(unknown) rad3delta
• par1delta par2delta
• pcn1-3(H44A aa) rad1delta
• pcn1-3(H44A aa) rad9delta
• pol1-ts13(470-472 Δaa) rad26.a14(C510CNPLIVC)
• pot1delta rqh1-K547A(aa)
• rad3-ts(unknown) rqh1delta
• spb70-U12(L442P,N485S aa) spp2-8(unknown)
• srw1delta wee1-50(G850E aa)

FYPO:0001054 - cut, elongated cell

References:

• PMID:11313465
• PMID:12724426
• PMID:9571240

Genes:

• cdc10 (SPBC336.12c)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• srw1 (SPAC144.13c)
• top3 (SPBC16G5.12c)

Genotypes:

• cdc10-129(T429A aa) ste9-B36(unknown)
• cds1-T8A,T11A(aa) chk1delta
• top3+(wild type) top3-Y330F(aa)[Overexpression]

FYPO:0001053 - cut, normal size cell

References:

• PMID:28513584
• PMID:31980821
• PMID:7700230
• PMID:8121488

Genes:

• ase1 (SPAPB1A10.09)
• bqt4 (SPBC19C7.10)
• cdc10 (SPBC336.12c)
• cdc18 (SPBC14C8.07c)
• cdc20 (SPBC25H2.13c)
• cdc6 (SPBC336.04)
• chk1 (SPCC1259.13)
• cut7 (SPAC25G10.07c)
• klp9 (SPBC15D4.01c)
• pkl1 (SPAC3A11.14c)
• rum1 (SPBC32F12.09)
• ter1 (SPNCRNA.214)

Genotypes:

• ase1+(wild type)[Knockdown] cut7delta pkl1delta
• bqt4delta ter1delta
• cdc10-129(T429A aa) rum1delta
• cdc18-K46(unknown) chk1delta
• cdc20-M10(unknown) chk1delta
• cdc6-ts1(AP143VS aa) chk1delta
• cdc6-ts2(E271K aa) chk1delta
• cdc6-ts3(R1064Q aa) chk1delta
• cut7delta klp9+(wild type)[Knockdown] pkl1delta

FYPO:0001052 - cut, small cell

References:

• PMID:12093738
• PMID:1427071
• PMID:18414064
• PMID:7796804
• PMID:8087848
• PMID:9398669
• PMID:9739083

Genes:

• cdc10 (SPBC336.12c)
• cdc13 (SPBC582.03)
• cdc18 (SPBC14C8.07c)
• cdc2 (SPBC11B10.09)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• hus1 (SPAC20G4.04c)
• hus5 (SPAC30D11.13)
• mik1 (SPBC660.14)
• orc5 (SPBC646.14c)
• rad1 (SPAC1952.07)
• rad17 (SPAC14C4.13)
• rad3 (SPBC216.05)
• rqh1 (SPAC2G11.12)
• wee1 (SPCC18B5.03)

Genotypes:

• cdc10-129(T429A aa) cdc13+(wild type)[Overexpression] cdc2+(wild type)[Overexpression]
• cdc18-C(150-577),T374A(1-149,T374A aa)[Overexpression] mik1delta wee1-50(G850E aa)
• cdc18-C(150-577),T374A(1-149,T374A aa)[Overexpression] rad1-1(unknown)
• cdc18-C(150-577)(1-149 Δaa)[Overexpression] mik1delta wee1-50(G850E aa)
• cdc18-C(150-577)(1-149 Δaa)[Overexpression] rad1-1(unknown)
• cdc2-3w(C67Y aa) wee1-50(G850E aa)
• cds1delta orc5-H19(V43A,C71R,Y177C,P191S,I352T aa)
• chk1delta orc5-H19(V43A,C71R,Y177C,P191S,I352T aa)
• hus1-14(unknown) wee1-50(G850E aa)
• hus2-22(W789*) wee1-50(G850E aa)
• hus5.17(G253T nt) wee1-50(G850E aa)
• mik1delta wee1-50(G850E aa)
• rad1-h24(unknown) wee1-50(G850E aa)
• rad17-h11(unknown) wee1-50(G850E aa)
• rad3-h1(unknown) wee1-50(G850E aa)

FYPO:0003286 - decreased mitotic chromosome condensation

References:

• PMID:21633354
• PMID:26869222

Genes:

• cdc25 (SPAC24H6.05)
• cut3 (SPBC146.03c)
• sfc3 (SPBC336.07)

Genotypes:

• cdc25-22(C532Y aa)[Knockdown] cut3-477(S1147P aa)[Knockdown]
• cut3-477(S1147P aa) sfc3-1(unknown)

FYPO:0005424 - decreased mitotic chromosome condensation during telophase

References:

• PMID:21540296

Genes:

• cut14 (SPBP4H10.06c)
• nda3 (SPBC26H8.07c)

Genotypes:

• cut14-208(S861P aa) nda3-KM311(G93E aa)

FYPO:0005343 - decreased rate of mitotic spindle elongation during anaphase B

References:

• PMID:11967147
• PMID:19686686
• PMID:28513584
• PMID:29021344
• PMID:29167352
• PMID:30806623
• PMID:31089172
• PMID:31427431

Genes:

• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• klp9 (SPBC15D4.01c)
• peg1 (SPAC3G9.12)
• pkl1 (SPAC3A11.14c)

Genotypes:

• ase1-S640D,S683D,S688D,S693D(aa) klp9-S>D(S598D,S605D,S611D aa)
• ase1delta klp9-deltaCC1(421-461 Δaa)
• ase1delta klp9-deltaCC2(501-541 Δaa)
• cut7-122(M134T,T290K aa) klp9delta
• cut7-22(P1021S aa) klp9delta pkl1delta
• cut7-22(P1021S aa) pkl1delta
• cut7delta klp9-2(K333M aa) pkl1delta
• cut7delta klp9-deltaCC1(421-461 Δaa) pkl1delta
• cut7delta klp9-deltaCC2(501-541 Δaa) pkl1delta
• cut7delta peg1+(wild type)[Knockdown] pkl1delta
• cut7delta pkl1delta
• dis1delta klp5-Q582P(aa)
• klp5delta klp6delta

FYPO:0006559 - delayed onset of mitotic spindle disassembly

References:

• PMID:36006032

Genes:

• par1 (SPCC188.02)
• par2 (SPAC6F12.12)

Genotypes:

• par1delta par2delta

FYPO:0002636 - delayed onset of mitotic spindle elongation

References:

• PMID:25987607

Genes:

• cut7 (SPAC25G10.07c)
• msd1 (SPBC13E7.06)

Genotypes:

• cut7-21(M394T aa) msd1delta

FYPO:0006049 - fluctuating mitotic spindle length

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0003757 - incomplete mitotic sister chromatid segregation

References:

• PMID:3040264

Genes:

• nda3 (SPBC26H8.07c)
• top2 (SPBC1A4.03c)

Genotypes:

• nda3-KM311(G93E aa) top2-342(ts)(unknown)

FYPO:0003970 - incomplete mitotic sister chromatid segregation, with chromatin bridge

References:

• PMID:20383139

Genes:

• hhp2 (SPAC23C4.12)
• rec8 (SPBC29A10.14)

Genotypes:

• hhp2+(wild type)[Overexpression] rec8+(wild type)[Overexpression]
• hhp2delta rec8+(wild type)[Overexpression]

FYPO:0004098 - incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass

References:

• PMID:21540296

Genes:

• nda3 (SPBC26H8.07c)
• top2 (SPBC1A4.03c)

Genotypes:

• nda3-KM311(G93E aa) top2-191(unknown)
• nda3-KM311(G93E aa) top2-342(G972D aa)

FYPO:0007071 - increased rate of mitotic spindle elongation during anaphase A

References:

• PMID:31427431

Genes:

• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)

Genotypes:

• dis1delta klp5-Q582P(aa)

FYPO:0000228 - lagging mitotic chromosomes

References:

• PMID:10733588
• PMID:11861765
• PMID:12052869
• PMID:12242294
• PMID:12526748
• PMID:15908586
• PMID:18262494
• PMID:19362535
• PMID:19965387
• PMID:20929775
• PMID:21633354
• PMID:22281223
• PMID:23050226
• PMID:28974540
• PMID:31000521
• PMID:31427431
• PMID:31895039
• PMID:35194019
• PMID:38830897

Genes:

• alm1 (SPAC1486.04c)
• alp14 (SPCC895.07)
• ark1 (SPCC320.13c)
• bdf2 (SPAC631.02)
• bir1 (SPCC962.02c)
• bub1 (SPCC1322.12c)
• cbh1 (SPAC9E9.10c)
• cbp1 (SPBC1105.04c)
• chp1 (SPAC18G6.02c)
• chp2 (SPBC16C6.10)
• clr4 (SPBC428.08c)
• clr6 (SPBC36.05c)
• dam1 (SPAC589.08c)
• dcr1 (SPCC188.13c)
• dfp1 (SPCC550.13)
• dis1 (SPCC736.14)
• eso1 (SPBC16A3.11)
• hht1 (SPAC1834.04)
• hht2 (SPBC8D2.04)
• hht3 (SPBC1105.11c)
• hrk1 (SPAC23C4.03)
• hrp1 (SPAC1783.05)
• hrp3 (SPAC3G6.01)
• hta1 (SPCC622.08c)
• hta2 (SPAC19G12.06c)
• klp5 (SPBC2F12.13)
• mal2 (SPAC25B8.14)
• mis4 (SPAC31A2.05c)
• mph1 (SPBC106.01)
• nda3 (SPBC26H8.07c)
• pds5 (SPAC110.02)
• pef1 (SPCC16C4.11)
• pht1 (SPBC11B10.10c)
• pph3 (SPBC26H8.05c)
• psm3 (SPAC10F6.09c)
• pst1 (SPBC12C2.10c)
• ras1 (SPAC17H9.09c)
• sgo2 (SPAC15A10.15)
• sor1 (SPAC9E9.05)
• spt2 (SPCC1393.02c)
• swi6 (SPAC664.01c)
• tea1 (SPCC1223.06)

Genotypes:

• alm1delta ark1-T7(unknown)
• alp14delta mal2-1(E277K aa)
• bdf2delta dcr1delta
• bir1-CD(bir1-CD-fusion) hht1-T3A(T4A aa) hht2-T3A(T4A aa) hht3-T3A(T4A aa) hta1-S121A(S122A aa) hta2-S121A(S122A aa)
• bub1-KD(K762R,D900N aa) hta1-S121A(S122A aa) hta2-S121A(S122A aa)
• bub1delta mph1delta
• cbh1delta cbp1::ura4(disruption)
• chp1-D48S,D51S(aa) clr4delta->clr4+(reintroduced clr4+)
• chp1-E23V(aa) clr4delta->clr4+(reintroduced clr4+)
• chp1-N59A(aa) clr4delta->clr4+(reintroduced clr4+)
• chp1-V24M(aa) clr4delta->clr4+(reintroduced clr4+)
• chp2delta dfp1-3A(P448A,V450A,I452A aa)
• chp2delta dfp1-3A(P448A,V450A,I452A aa) swi6delta
• chp2delta swi6delta
• clr6-1(G269D aa) pst1-1(W1305*)
• dam1-A8-ts(H126R,E149G aa) klp5delta
• dfp1-3A(P448A,V450A,I452A aa) swi6delta
• dfp1-CFP-2CD(dfp1-CFP-swi6(69-215)-swi6(69-215)) swi6delta
• dis1delta klp5-Q582P(aa)
• eso1-G799D(aa) pds5delta
• eso1-G799D(aa) sor1delta
• eso1-G799D(aa) spt2delta
• hht1-T3A(T4A aa) hht2-T3A(T4A aa) hht3-T3A(T4A aa)
• hht1-T3A(T4A aa) hht2-T3A(T4A aa) hht3-T3A(T4A aa) hta1-S121A(S122A aa) hta2-S121A(S122A aa)
• hht1-T3A(T4A aa) hht2-T3A(T4A aa) hht3-T3A(T4A aa) sgo2delta
• hrk1delta sgo2delta
• hrp1delta hrp3delta
• hta1-R18A(R19A aa) hta2-R18A(R19A aa) pht1+(wild type)[Knockdown]
• hta1-S121A(S122A aa) hta2-S121A(S122A aa)
• mis4-367(G1487D aa) pef1-as(F78A aa)
• mis4-367(G1487D aa) pef1delta
• mis4-I803M(aa) pph3delta psm3-K105N,K106N(aa)
• nda3-KM311(G93E aa) pds5delta
• pph3delta psm3-K105N,K106N(aa)
• ras1delta tea1delta

FYPO:0004101 - lagging mitotic chromosomes, with complete sister chromatid separation

References:

• PMID:24239120
• PMID:27146110
• PMID:28455357

Genes:

• ase1 (SPAPB1A10.09)
• dcn1 (SPBC839.03c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mad2 (SPBC20F10.06)

Genotypes:

• ase1delta klp5delta
• dcn1delta mad2delta
• klp5delta klp6delta

FYPO:0004382 - meroterically attached lagging mitotic chromosomes

References:

• PMID:20739936
• PMID:28343969

Genes:

• bir1 (SPCC962.02c)
• cdc13 (SPBC582.03)
• hrk1 (SPAC23C4.03)
• pds5 (SPAC110.02)

Genotypes:

• bir1-8D(S202D,S229D,S244D,S278D,S294D,T393D,T831D,T908D aa) cdc13-M7(E255G aa)
• hrk1-KD-CD(hrk1-K184R-CD) pds5-him(P84A,D85A,P87A aa)

FYPO:0003012 - mitosis with unreplicated DNA

References:

• PMID:11988741
• PMID:1427071
• PMID:9571240

Genes:

• cdc10 (SPBC336.12c)
• cdc18 (SPBC14C8.07c)
• cdc2 (SPBC11B10.09)
• cdc25 (SPAC24H6.05)
• cds1 (SPCC18B5.11c)
• orc1 (SPBC29A10.15)
• srw1 (SPAC144.13c)

Genotypes:

• cdc10-129(T429A aa) ste9-B36(unknown)
• cdc18+(wild type)[Knockdown] cdc18-K46(unknown) orp1-4(unknown)
• cdc18-K46(unknown) cds1+(wild type)[Overexpression] orp1-4(unknown)
• cdc18-K46(unknown) orp1-4(unknown)
• cdc2-3w(C67Y aa) cdc25delta

FYPO:0000283 - mitotic chromosome fragmentation upon segregation

References:

• PMID:16738311

Genes:

• bub1 (SPCC1322.12c)
• cid12 (SPCC663.12)

Genotypes:

• bub1delta cid12delta

FYPO:0006475 - mitotic spindle collapse

References:

• PMID:28513584
• PMID:31532702
• PMID:31618856

Genes:

• alp14 (SPCC895.07)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• moa1 (SPAC15E1.07c)
• peg1 (SPAC3G9.12)
• pkl1 (SPAC3A11.14c)

Genotypes:

• alp14-26(C450R aa) dis1delta
• cut7delta moa1delta pkl1delta
• cut7delta peg1+(wild type)[Knockdown] pkl1delta

FYPO:0008007 - mitotic spindle collapse during anaphase B elongation with progressive spindle pole congression

References:

• PMID:19948483

Genes:

• ase1 (SPAPB1A10.09)
• rad21 (SPCC338.17c)

Genotypes:

• ase1delta rad21-K1(unknown)

FYPO:0006171 - mitotic spindle elongation during anaphase A

References:

• PMID:11967147

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta klp6delta

FYPO:0003758 - mitotic spindle elongation without chromosome separation

References:

• PMID:21540296

Genes:

• nda3 (SPBC26H8.07c)
• top2 (SPBC1A4.03c)

Genotypes:

• nda3-KM311(G93E aa) top2-191(unknown)
• nda3-KM311(G93E aa) top2-342(G972D aa)

FYPO:0007859 - nuclear division in absence of mitotic spindle

References:

• PMID:20967237

Genes:

• cdc11 (SPCC1739.11c)
• cut1 (SPCC5E4.04)
• cut11 (SPAC1786.03)

Genotypes:

• cdc11-119(unknown) cut1-645(unknown)
• cdc11-119(unknown) cut11-2(C525R aa)

FYPO:0001046 - premature mitosis

References:

• PMID:1464318
• PMID:37787465
• PMID:7774573
• PMID:8497322
• PMID:9042863

Genes:

• cdc2 (SPBC11B10.09)
• cdc25 (SPAC24H6.05)
• chk1 (SPCC1259.13)
• mik1 (SPBC660.14)
• pyp3 (SPAC11E3.09)
• wee1 (SPCC18B5.03)

Genotypes:

• cdc2-33(A177T aa) cdc2-DL50(240-242 Δnt)[Overexpression]
• cdc2-3w(C67Y aa) cdc25delta
• cdc2-3w(C67Y aa) pyp3+(wild type)[Overexpression]
• chk1::ura4(chk1::ura4@(CU329672.1:1060123_1061101delins)) wee1-50(G850E aa)
• mik1delta wee1-50(G850E aa)
• pyp3+(wild type)[Overexpression] wee1-50(G850E aa)

FYPO:0007566 - premature mitotic chromosome condensation

References:

• PMID:11927555

Genes:

• cut15 (SPCC962.03c)
• cut3 (SPBC146.03c)
• fin1 (SPAC19E9.02)
• top2 (SPBC1A4.03c)

Genotypes:

• cut15-85(G419S,G450S aa) fin1+(wild type)[Overexpression]
• cut3-477(S1147P aa) fin1+(wild type)[Overexpression]
• fin1+(wild type)[Overexpression] top2-191(unknown)

FYPO:0007961 - transient abrupt spindle length decrease at anaphase onset

References:

• PMID:24239120

Genes:

• ase1 (SPAPB1A10.09)
• klp5 (SPBC2F12.13)

Genotypes:

• ase1delta klp5delta

FYPO:0003241 - unequal mitotic sister chromatid segregation

References:

• PMID:10440376
• PMID:11359920
• PMID:11882285
• PMID:14730319
• PMID:15483052
• PMID:16394105
• PMID:17531816
• PMID:18077559
• PMID:18262494
• PMID:22375062
• PMID:27901072
• PMID:28475874
• PMID:28827290
• PMID:29021344
• PMID:35970865
• PMID:38166399
• PMID:38830897

Genes:

• ago1 (SPCC736.11)
• alp5 (SPBP23A10.08)
• ams2 (SPCC290.04)
• atb2 (SPBC800.05c)
• bub1 (SPCC1322.12c)
• bub3 (SPAC23H3.08c)
• cnp1 (SPBC1105.17)
• cut7 (SPAC25G10.07c)
• cut9 (SPAC6F12.15c)
• dam1 (SPAC589.08c)
• eso1 (SPBC16A3.11)
• exo1 (SPBC29A10.05)
• hsk1 (SPBC776.12c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• klp9 (SPBC15D4.01c)
• mad1 (SPBC3D6.04c)
• mad2 (SPBC20F10.06)
• mal3 (SPAC18G6.15)
• mis15 (SPBP22H7.09c)
• mis16 (SPCC1672.10)
• mis4 (SPAC31A2.05c)
• msc1 (SPAC343.11c)
• nda3 (SPBC26H8.07c)
• pkl1 (SPAC3A11.14c)
• rad21 (SPCC338.17c)
• rad52 (SPAC30D11.10)
• rec8 (SPBC29A10.14)
• sgo2 (SPAC15A10.15)
• sor1 (SPAC9E9.05)
• spt6 (SPAC1F7.01c)
• swi6 (SPAC664.01c)
• tas3 (SPBC83.03c)
• wee1 (SPCC18B5.03)

Genotypes:

• ago1-F276A(aa) tas3-W265A,G266A(aa)
• alp5-1134(S402N aa) bub1delta
• ams2-MZF(C375A,C378A aa)[Overexpression] cnp1-1(L87Q aa)
• ams2delta wee1-50(G850E aa)
• atb2-983(V260I aa) bub1delta
• atb2-983(V260I aa) bub3delta mal3+(wild type)[Overexpression]
• cut7delta klp9-2(K333M aa) pkl1delta
• cut9-665(A535T aa) spt6delta
• dam1-A8-ts(H126R,E149G aa) klp5delta
• dam1-A8-ts(H126R,E149G aa) klp6delta
• dam1-S143A(aa) klp5delta
• dam1-S143A(aa) nda3-KM311(G93E aa)
• eso1-G799D(aa) sor1delta
• exo1delta rad52delta
• hsk1-89(L339P,E403K,L416P aa) rad21-K1(unknown)
• mad1delta wee1-50(G850E aa)
• mad2delta mis4-242(G1326E aa)
• mis15-68(W113R aa) msc1delta
• mis16-53(unknown) msc1+(wild type)[Overexpression]
• mis16-53(unknown) msc1delta
• rad21delta rec8+(wild type)[Overexpression]
• sgo2delta swi6delta

FYPO:0006822 - viable small vegetative cell with normal cell growth rate

References:

• PMID:11027257
• PMID:12399381
• PMID:12456722
• PMID:1464318
• PMID:15629716
• PMID:1588914
• PMID:16453724
• PMID:16611237
• PMID:1703321
• PMID:17952063
• PMID:19474789
• PMID:19474792
• PMID:19546237
• PMID:21813639
• PMID:2245912
• PMID:23333317
• PMID:24006256
• PMID:24047646
• PMID:24297439
• PMID:24316795
• PMID:2474475
• PMID:26366556
• PMID:27398807
• PMID:30853434
• PMID:31644361
• PMID:31911490
• PMID:32361273
• PMID:3442828
• PMID:3448096
• PMID:6828164
• PMID:7217015
• PMID:7262540
• PMID:8437586
• PMID:8497322
• PMID:8631307
• PMID:9034337
• PMID:9042863
• PMID:9636183
• PMID:9843572

Genes:

• ade6 (SPCC1322.13)
• alp4 (SPBC365.15)
• bud6 (SPAC15A10.16)
• cbf11 (SPCC736.08)
• cdc1 (SPAC27E2.05)
• cdc2 (SPBC11B10.09)
• cdc25 (SPAC24H6.05)
• cdc28 (SPBC19C2.01)
• cdr1 (SPAC644.06c)
• cdr2 (SPAC57A10.02)
• chk1 (SPCC1259.13)
• cut1 (SPCC5E4.04)
• cut12 (SPBC649.05)
• dnt1 (SPBC25D12.02c)
• gcn2 (SPBC36B7.09)
• gpa2 (SPAC23H3.13c)
• mcb1 (SPAC1687.04)
• mcm4 (SPCC16A11.17)
• mcs2 (SPBP16F5.02)
• mcs4 (SPBC887.10)
• mid1 (SPCC4B3.15)
• mob2 (SPCC970.04c)
• nif1 (SPBC23G7.04c)
• orb6 (SPAC821.12)
• pab1 (SPAC227.07c)
• par1 (SPCC188.02)
• pka1 (SPBC106.10)
• pmk1 (SPBC119.08)
• pom1 (SPAC2F7.03c)
• pyp2 (SPAC19D5.01)
• pyp3 (SPAC11E3.09)
• rad1 (SPAC1952.07)
• rad3 (SPBC216.05)
• res2 (SPAC22F3.09c)
• rnc1 (SPCC757.09c)
• sal3 (SPCC1840.03)
• sck1 (SPAC1B9.02c)
• slx8 (SPBC3D6.11c)
• spo12 (SPAC3F10.15c)
• spp2 (SPBC17D11.06)
• srk1 (SPCC1322.08)
• sup3 (SPATRNASER.03)
• tea1 (SPCC1223.06)
• tor1 (SPBC30D10.10c)
• wee1 (SPCC18B5.03)
• win1 (SPAC1006.09)
• wis1 (SPBC409.07c)
• wis2 (SPAC1B3.03c)
• wis4 (SPAC9G1.02)

Genotypes:

• ade6-704(C215*) sup3-G35C(nt) wee1-112(unknown opal)
• ade6-704(C215*) wee1-112(unknown opal)
• alp4-C(566-784)(1-565 Δaa)[Overexpression] wee1-50(G850E aa)
• bud6delta pom1delta305N(10-303 Δaa)
• cbf11delta pka1delta
• cdc1-7(unknown) cdc2-1w(G146D aa)
• cdc1-7(unknown) wee1-6(unknown)
• cdc2-1w(G146D aa) cdc25-22(C532Y aa) cut12.s11(G71V aa)
• cdc2-1w(G146D aa) cut12.s11(G71V aa)
• cdc2-1w(G146D aa) dnt1delta
• cdc2-1w(G146D aa) mcs2-75(unknown)
• cdc2-1w(G146D aa) spo12+(wild type)[Overexpression]
• cdc2-1w(G146D aa) wis1+(wild type)[Overexpression]
• cdc2-1w(G146D aa) wis2+(wild type)[Overexpression]
• cdc2-1w(G146D aa) wis4+(wild type)[Overexpression]
• cdc2-33(A177T aa) wee1-6(unknown)
• cdc2-3w(C67Y aa) cdc25-22(C532Y aa) cut12.s11(G71V aa)
• cdc2-3w(C67Y aa) cut12.s11(G71V aa)
• cdc2-3w(C67Y aa) mcs1-77(unknown) wee1-50(G850E aa)
• cdc2-3w(C67Y aa) mcs4-13(unknown) wee1-50(G850E aa)
• cdc2-3w(C67Y aa) par1delta
• cdc2-3w(C67Y aa) spo12+(wild type)[Overexpression]
• cdc2-3w(C67Y aa) win1-1(unknown)
• cdc2-3w(C67Y aa) wis1+(wild type)[Overexpression]
• cdc2-3w(C67Y aa) wis2+(wild type)[Overexpression]
• cdc2-3w(C67Y aa) wis4+(wild type)[Overexpression]
• cdc2-4w(C67F aa) cdc25-22(C532Y aa)
• cdc2-C67I(aa) wee1-50(G850E aa)
• cdc2-C67L(aa) wee1-50(G850E aa)
• cdc2-C67V(aa) wee1-50(G850E aa)
• cdc2-C67W(aa) wee1-50(G850E aa)
• cdc2-L7(P208S aa) wee1-6(unknown)
• cdc2-M26(P137S aa) wee1-6(unknown)
• cdc2-M35(G43E aa) wee1-6(unknown)
• cdc2-M55(unknown) wee1-6(unknown)
• cdc2-M63(G227C aa) wee1-6(unknown)
• cdc2-Y15F(aa) cdc25-22(C532Y aa)
• cdc2-Y15F(aa) cdc25delta
• cdc2-Y15F(aa) chk1+(wild type)[Overexpression]
• cdc2-Y15F(aa) tor1delta
• cdc2-d1(62-65 Δaa) wee1-50(G850E aa)
• cdc21-M68(unknown) rad1-1(unknown)
• cdc25+(wild type)[Overexpression] cut12.s11(G71V aa)
• cdc25-22(C532Y aa) cut12.s11(G71V aa) wee1-50(G850E aa)
• cdc25-22(C532Y aa) pyp3+(wild type)[Overexpression]
• cdc25-22(C532Y aa) wee1-50(G850E aa)
• cdc25-22(C532Y aa) wee1-6(unknown)
• cdc25-GFP-NLS sal3delta
• cdc25delta cut12-PDSA(G71V,I72A,L73A,K83A,V85A,F87A aa)
• cdc28-(unknown) cut1-(unknown)
• cdr1+(wild type)[Overexpression] cdr1delta cdr2delta
• cdr1+(wild type)[Overexpression] wee1-4A(S771A,S788A,S794A,S798A aa)
• cdr1-76(unknown) wee1-50(G850E aa)
• cdr2+(wild type)[Overexpression] pom1delta
• cdr2-97(unknown) wee1-50(G850E aa)
• cdr2-D1(disruption) wee1-50(G850E aa)
• cdr2-S755A(aa) pom1delta
• cdr2-S755A-S758A(S755A,S758A aa) pom1delta
• cdr2-S755A-S758A(S755A,S758A aa) pom1delta305N(10-303 Δaa)
• chk1+(wild type)[Overexpression] wee1delta
• chk1::ura4(chk1::ura4@(CU329672.1:1060123_1061101delins)) wee1-50(G850E aa)
• chk1delta mcb1+(wild type)[Overexpression]
• chk1delta spp2-8(unknown)
• chk1delta spp2-9(unknown)
• cut12.s11(G71V aa) wee1-50(G850E aa)
• dnt1delta wee1-50(G850E aa)
• gcn2delta pyp2delta
• gpa2delta sck1delta
• mcb1+(wild type)[Overexpression] rad3delta
• mid1-9A(S110A,S127A,S218A,S227A,S329A,S432A,S452A,S464A,S531A aa) pom1delta
• mob2+(wild type)[Overexpression] wee1-50(G850E aa)
• nif1delta pom1delta
• orb6+(wild type)[Overexpression] wee1-50(G850E aa)
• pab1-1(I228ITEVI) slx8-29(unknown)
• pmk1delta rnc1delta
• pom1+(wild type)[Overexpression] wee1-ts(unknown)
• pom1delta tea1delta
• pom1delta wee1-50(G850E aa)
• pom1delta wis1-DD(S469D,T473D aa)
• rnc1delta wis1-DD(S469D,T473D aa)
• spo12+(wild type)[Overexpression] wee1-50(G850E aa)
• srk1delta wee1-50(G850E aa)
• wee1-50(G850E aa) win1-1(unknown)
• wee1-50(G850E aa) wis1+(wild type)[Overexpression]
• wee1-50(G850E aa) wis2+(wild type)[Overexpression]
• wee1-50(G850E aa) wis4+(wild type)[Overexpression]
• wee1-6(unknown) win1-1(unknown)

FYPO:0000337 - abnormal mitosis

References:

• PMID:10718196
• PMID:11134033
• PMID:11882285
• PMID:3040264
• PMID:32848252

Genes:

• ark1 (SPCC320.13c)
• int6 (SPBC646.09c)
• rad21 (SPCC338.17c)
• top2 (SPBC1A4.03c)
• zas1 (SPBC1198.04c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• int6delta
• rad21-RERE(R179E,R231E aa)
• top2-250(cs)(unknown)
• zas1-ts34(unknown)

FYPO:0004588 - abnormal mitosis following normal mitosis

References:

• PMID:12000964
• PMID:19330768

Genes:

• alp1 (SPBC11C11.04c)
• cnd2 (SPCC306.03c)

Genotypes:

• alp1-1315(unknown)
• cnd2-1(A114T aa)

FYPO:0000214 - abnormal mitotic chromosome condensation

References:

• PMID:10485849
• PMID:15507118
• PMID:18158900
• PMID:1846086
• PMID:1855255
• PMID:23695302
• PMID:25764183
• PMID:28825727
• PMID:29735745
• PMID:9285594

Genes:

• ark1 (SPCC320.13c)
• cnd1 (SPBC776.13)
• cnd2 (SPCC306.03c)
• cnd3 (SPCC188.03)
• cut14 (SPBP4H10.06c)
• cut3 (SPBC146.03c)
• mbx2 (SPBC317.01)
• pim1 (SPBC557.03c)
• prr1 (SPAC8C9.14)
• res2 (SPAC22F3.09c)
• sds22 (SPAC4A8.12c)
• sim3 (SPBC577.15c)
• toe1 (SPAC1399.05c)
• zas1 (SPBC1198.04c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• cnd1-G984R(aa)
• cnd1-H1133P(aa)
• cnd1-L193P(aa)
• cnd1-L331P(aa)
• cnd1-L685P(aa)
• cnd1-M951R(aa)
• cnd1::ura4+
• cnd2-A708V(aa)
• cnd2-CN385(unknown)
• cnd2::ura4+
• cnd3-AID[Knockdown]
• cnd3-C101R(aa)
• cnd3-K627E(aa)
• cnd3-L126P(aa)
• cnd3-L269P(aa)
• cnd3-L640R(aa)
• cnd3-L643P(aa)
• cnd3-L662P(aa)
• cnd3-Q588P(aa)
• cnd3-W717R(aa)
• cnd3-Y669N(aa)
• cnd3::ura4+
• cut14-208(S861P aa)
• cut14-296(unknown)
• cut14-587(unknown)
• cut3-477(S1147P aa)
• cut3-T19A,T51A,T86A(aa)[Overexpression]
• cut3-T19A(aa)[Overexpression]
• mbx2+(wild type)[Overexpression]
• pim1-46(unknown)
• prr1+(wild type)[Overexpression]
• res2+(wild type)[Overexpression]
• sds22+(wild type)/sds22delta
• sds22delta
• sim3-143(G81E aa)
• sim3-205(E207K aa)
• toe1+(wild type)[Overexpression]
• zas1-w5(E549K aa)

FYPO:0000141 - abnormal mitotic sister chromatid segregation

References:

• PMID:10077566
• PMID:10733588
• PMID:10779336
• PMID:11027263
• PMID:11349150
• PMID:11432827
• PMID:11598020
• PMID:11685532
• PMID:11861765
• PMID:11864908
• PMID:11967147
• PMID:12426374
• PMID:12477395
• PMID:12615979
• PMID:12676088
• PMID:12764130
• PMID:12773392
• PMID:14508607
• PMID:14742702
• PMID:15147872
• PMID:15331764
• PMID:15369671
• PMID:15371542
• PMID:15466421
• PMID:15483052
• PMID:15525536
• PMID:15743824
• PMID:15743828
• PMID:16079914
• PMID:16199877
• PMID:16611237
• PMID:16855021
• PMID:17352737
• PMID:17442892
• PMID:18622392
• PMID:18799626
• PMID:19168987
• PMID:19330768
• PMID:21256022
• PMID:21445296
• PMID:21965289
• PMID:22281223
• PMID:22660415
• PMID:23091701
• PMID:23695302
• PMID:24945319
• PMID:25398909
• PMID:25847133
• PMID:26446992
• PMID:26581324
• PMID:26869222
• PMID:27053664
• PMID:27398807
• PMID:27548313
• PMID:28974540
• PMID:29109278
• PMID:29194511
• PMID:29735745
• PMID:30635289
• PMID:32062975
• PMID:32723864
• PMID:33125111
• PMID:33137104
• PMID:33468217
• PMID:34810257
• PMID:36200823
• PMID:38084929
• PMID:39485795
• PMID:41786187
• PMID:7768995
• PMID:7865880
• PMID:8313892
• PMID:8972853
• PMID:9490640

Genes:

• ace2 (SPAC6G10.12c)
• alp1 (SPBC11C11.04c)
• alp14 (SPCC895.07)
• alp16 (SPCC4G3.19)
• alp4 (SPBC365.15)
• alp5 (SPBP23A10.08)
• alp6 (SPBC428.20c)
• alp7 (SPAC890.02c)
• apc13 (SPBC28E12.01c)
• ase1 (SPAPB1A10.09)
• ask1 (SPBC27.02c)
• bub1 (SPCC1322.12c)
• bub3 (SPAC23H3.08c)
• cay1 (SPBC2F12.12c)
• cbp1 (SPBC1105.04c)
• cdc25 (SPAC24H6.05)
• cdc5 (SPAC644.12)
• cds1 (SPCC18B5.11c)
• chp1 (SPAC18G6.02c)
• clp1 (SPAC1782.09c)
• clr6 (SPBC36.05c)
• cnp1 (SPBC1105.17)
• cnp20 (SPBC800.13)
• cnp3 (SPBC1861.01c)
• cut1 (SPCC5E4.04)
• cut14 (SPBP4H10.06c)
• cut3 (SPBC146.03c)
• cut9 (SPAC6F12.15c)
• dad2 (SPAC1805.07c)
• dis2 (SPBC776.02c)
• dpb3 (SPCC16C4.22)
• dpb4 (SPBC3D6.09)
• dre4 (SPAC13C5.02)
• dsk1 (SPBC530.14c)
• eng1 (SPAC821.09)
• esc1 (SPAC56F8.16)
• eso1 (SPBC16A3.11)
• est1 (SPBC2D10.13)
• fep1 (SPAC23E2.01)
• fin1 (SPAC19E9.02)
• fzo1 (SPBC1706.03)
• hsk1 (SPBC776.12c)
• hus5 (SPAC30D11.13)
• ibp1 (SPBC839.07)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• loz1 (SPAC25B8.19c)
• mad2 (SPBC20F10.06)
• mal2 (SPAC25B8.14)
• mis14 (SPAC688.02c)
• mis15 (SPBP22H7.09c)
• mis16 (SPCC1672.10)
• mis17 (SPBC21.01)
• mis18 (SPCC970.12)
• mis6 (SPAC1687.20c)
• mlo2 (SPBC4.05)
• mph1 (SPBC106.01)
• ndc80 (SPBC11C11.03)
• nrm1 (SPBC16A3.07c)
• nse3 (SPCC645.04)
• nsk1 (SPAC3G9.01)
• nuf2 (SPAC27F1.04c)
• orc4 (SPBP23A10.13)
• pab1 (SPAC227.07c)
• pcp1 (SPAC6G9.06c)
• pcr1 (SPAC21E11.03c)
• pds5 (SPAC110.02)
• pfd1 (SPBC1D7.01)
• pfd2 (SPAC227.10)
• pfd3 (SPAC3H8.07c)
• pfd4 (SPAC227.05)
• pfd5 (SPBC215.02)
• pfd6 (SPAC3A11.13)
• pfs2 (SPAC12G12.14c)
• plo1 (SPAC23C11.16)
• pot1 (SPAC26H5.06)
• ppc1 (SPCC4B3.18)
• prw1 (SPAC29A4.18)
• psf2 (SPBC725.13c)
• pst2 (SPAC23C11.15)
• rad60 (SPBC1921.02)
• rbm10 (SPAC57A7.13)
• res2 (SPAC22F3.09c)
• rna14 (SPAC6F12.17)
• rqh1 (SPAC2G11.12)
• rsc58 (SPAC1F3.07c)
• scm3 (SPAPB1A10.02)
• sfh1 (SPCC16A11.14)
• skb15 (SPCC16C4.08c)
• skp1 (SPBC409.05)
• sld5 (SPBP4H10.21c)
• slx8 (SPBC3D6.11c)
• snf21 (SPAC1250.01)
• spc7 (SPCC1020.02)
• taz1 (SPAC16A10.07c)
• tdk1 (SPCC330.04c)
• toe3 (SPAPB24D3.01)
• ulp2 (SPAC17A5.07c)
• wee1 (SPCC18B5.03)
• yox1 (SPBC21B10.13c)
• zas1 (SPBC1198.04c)
• SPAC343.20

Genotypes:

• NLS-alp4-C(566-784)(NLS-alp4(566-784))[Overexpression]
• SPAC343.20delta
• ace2delta
• alp1-1315(unknown)
• alp14-1270(unknown)
• alp16delta
• alp4+(wild type)[Overexpression]
• alp4-1891(unknown)
• alp4-C(566-784)(1-565 Δaa)[Overexpression]
• alp5-1134(S402N aa)
• alp6+(wild type)[Overexpression]
• alp6-N(1-581)(582-832 Δaa)[Overexpression]
• alp7-738(unknown)
• apc13+(wild type)[Knockdown]
• ase1delta
• ask1delta
• bub1delta
• bub3delta
• cay1delta
• cbp1::ura4(disruption)
• cdc25-22(C532Y aa)[Knockdown]
• cdc5delta
• cds1delta
• chp1(1-409)(410-960 Δaa)
• chp1deltaCD(2-79)(aa)
• clp1delta
• clr6-1(G269D aa)
• cnp1-P13A,P15A(aa)
• cnp20-14A(S3A,T8A,S12A,S13A,S14A,T21A,S23A,T29A,S31A,S33A,T36A,S39A,T43A,T45A aa)
• cnp3+(wild type)[Overexpression]
• cut1-206(L739C aa)
• cut14-208(S861P aa)
• cut3-477(S1147P aa)
• cut9-41(S348P aa)
• dad2delta
• dis2delta
• dpb3delta
• dpb4delta
• dre4-54(W117*)
• dsk1delta
• eng1delta
• esc1+(wild type)[Overexpression]
• eso1-G799D(aa)
• est1delta
• fep1+(wild type)[Overexpression]
• fin1delta
• fzo1delta
• hsk1-1312(S314I aa)
• hus5delta
• ibp1delta
• klp5N/klp6C(klp5(1-404)-Klp6(411-784))
• klp5delta
• klp6+(wild type)[Overexpression]
• loz1+(wild type)[Overexpression]
• mad2delta
• mal2-1(E277K aa)
• mis14-271(L106P aa)
• mis15-68(W113R aa)
• mis16-53(unknown)
• mis17(1-220)(221-440 Δaa)[Overexpression]
• mis17-362(S353P aa)
• mis18-262(G117D aa)
• mis6-302(G135E aa)
• mlo2+(wild type)[Overexpression]
• mph1-kd(D459A aa)
• mph1delta
• ndc80delta371-476(aa)
• ndc80delta400-476(aa)
• nrm1delta
• nse3-1(unknown)
• nse3-R254E(aa)
• nsk1delta
• nuf2-1(unknown)
• nuf2-2(unknown)
• nuf2-3(unknown)
• nuf2-4(unknown)
• nuf2delta
• orc4delta487-972(aa)[Overexpression]
• pab1-1(I228ITEVI)
• pcp1+(wild type)[Overexpression]
• pcr1+(wild type)[Overexpression]
• pds5-1(pds5::ura4)
• pds5delta
• pfd1delta
• pfd2delta
• pfd3delta
• pfd4delta
• pfd5delta
• pfd6delta
• pfs2-11(unknown)
• pfs2-3169(unknown)
• plo1-L577A(aa)
• pot1delta
• ppc1-537(T48I aa)
• ppc1-88(M209T aa)
• prw1delta
• psf2-209(R133K aa)
• pst2delta
• rad60-4(unknown)
• rbm10+(wild type)[Overexpression]
• res2delta
• rna14-11(R316Q aa)
• rqh1delta
• rsc58delta
• scm3-4A(H316A,C321A,C326A,C329A aa)[Ectopic]
• sfh1-13(E225D,K254E,P292Q aa)
• skb15+(wild type)[Knockdown]
• skp1-A7(I110T aa)
• sld5delta
• slx8-29(unknown)
• snf21-36(V404A,E461K,S566L,I571V aa)
• spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)
• spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
• spc7-23(T3887G,G4079T nt)
• spc7-C(unknown)[Overexpression]
• taz1delta
• tdk1+(wild type)/tdk1delta
• tdk1-1L(G119GSGGGSSG)
• toe3+(wild type)[Overexpression]
• ulp2delta
• wee1-50(G850E aa)
• yox1delta
• zas1-a1(W761*)
• zas1-aj3(K833*)
• zas1-w5(E549K aa)

FYPO:0005045 - abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation

References:

• PMID:19948483

Genes:

• rad21 (SPCC338.17c)

Genotypes:

• rad21-K1(unknown)

FYPO:0005046 - abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation

References:

• PMID:11069763
• PMID:12773392

Genes:

• alp13 (SPAC23H4.12)
• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)

Genotypes:

• alp13delta
• chp1delta
• csp10-439(unknown)

FYPO:0000131 - abnormal mitotic spindle elongation

References:

• PMID:11432827
• PMID:11861551
• PMID:16611237
• PMID:21920317
• PMID:8065367

Genes:

• alp14 (SPCC895.07)
• alp4 (SPBC365.15)
• bir1 (SPCC962.02c)
• cut8 (SPAC17C9.13c)
• rec12 (SPAC17A5.11)

Genotypes:

• NLS-alp4-C(566-784)(NLS-alp4(566-784))[Overexpression]
• alp14-1270(unknown)
• bir1+(wild type)[Knockdown]
• cut8-563(S201P aa)
• rec12delta

FYPO:0006302 - abolished intra-arm chromosome contact change during mitosis

References:

• PMID:28825727

Genes:

• ark1 (SPCC320.13c)
• cnd3 (SPCC188.03)
• cut14 (SPBP4H10.06c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• cnd3-AID[Knockdown]
• cut14-AID[Knockdown]

FYPO:0003844 - abolished mitotic chromosome condensation

References:

• PMID:10571085
• PMID:22645654
• PMID:9740803

Genes:

• bir1 (SPCC962.02c)
• cut14 (SPBP4H10.06c)
• cut15 (SPCC962.03c)

Genotypes:

• bir1delta
• cut14-Y1(L543S aa)
• cut15-122(C395R aa)[Knockdown]
• cut15-85(G419S,G450S aa)[Knockdown]

FYPO:0004622 - abolished mitotic spindle disassembly

References:

• PMID:15772152
• PMID:31276301
• PMID:32502403

Genes:

• apq12 (SPBC428.04)
• imp1 (SPBC1604.08c)
• klp8 (SPAC144.14)
• mto1 (SPCC417.07c)

Genotypes:

• apq12delta
• imp1delta
• klp8+(wild type)[Overexpression]
• mto1delta

FYPO:0003829 - abolished mitotic spindle elongation

References:

• PMID:11448769
• PMID:18362178

Genes:

• acr1 (SPBC17D1.04)
• clp1 (SPAC1782.09c)

Genotypes:

• acr1-936(unknown)
• clp1+(wild type)[Overexpression]

FYPO:0006174 - abolished mitotic spindle elongation during anaphase B

References:

• PMID:10398680
• PMID:10468581
• PMID:11882285
• PMID:25375240
• PMID:31615768

Genes:

• bir1 (SPCC962.02c)
• mis4 (SPAC31A2.05c)
• mis6 (SPAC1687.20c)
• peg1 (SPAC3G9.12)

Genotypes:

• bir1delta
• cls1-28(L797P aa)
• mis4-242(G1326E aa)
• mis6-302(G135E aa)

FYPO:0006173 - abolished mitotic spindle elongation during prophase

References:

• PMID:14742702
• PMID:19942852
• PMID:25987607

Genes:

• alp7 (SPAC890.02c)
• cut7 (SPAC25G10.07c)
• pcp1 (SPAC6G9.06c)

Genotypes:

• alp7-738(unknown)
• cut7-21(M394T aa)
• pcp1-15(I172T,K543E,I624T,E732G,A1022V,I1153V,H1163R aa)
• pcp1-18(L254S,L717P aa)

FYPO:0004830 - arrested mitotic spindle elongation during anaphase B

References:

• PMID:11554922
• PMID:9802907

Genes:

• bir1 (SPCC962.02c)
• cut1 (SPCC5E4.04)

Genotypes:

• cut1-206(L739C aa)
• cut17-275(A990T aa)

FYPO:0007862 - centromere clustering at nuclear periphery during nuclear division in absence of mitotic spindle

References:

• PMID:20967237

Genes:

• cdc11 (SPCC1739.11c)

Genotypes:

• cdc11-119(unknown)

FYPO:0000227 - chromosome loss during mitotic chromosome segregation

References:

• PMID:10462526
• PMID:11809834
• PMID:18799612
• PMID:19915592
• PMID:20230746
• PMID:23166349
• PMID:24963130
• PMID:25619765
• PMID:28974540
• PMID:30076928
• PMID:9649516
• PMID:9864354

Genes:

• alm1 (SPAC1486.04c)
• ams2 (SPCC290.04)
• bub1 (SPCC1322.12c)
• cdc24 (SPAC8F11.07c)
• cnp1 (SPBC1105.17)
• csi1 (SPBC2G2.14)
• dfp1 (SPCC550.13)
• kms2 (SPBC947.12)
• msc1 (SPAC343.11c)
• mst1 (SPAC637.12c)
• pht1 (SPBC11B10.10c)
• pof3 (SPCC338.16)
• rna14 (SPAC6F12.17)
• swr1 (SPAC11E3.01c)
• zfs1 (SPBC1718.07c)

Genotypes:

• alm1delta
• ams2+(wild type)[Overexpression]
• bub1delta/bub1delta
• cdc24-G1(G1301A nt)
• cnp1-halftail(1-11 Δaa)
• csi1delta
• dfp1+(wild type)[Overexpression]
• kms2+(wild type)[Knockdown]
• msc1delta
• mst1-L271P(aa)
• pht1-4KQ(K6Q,K8Q,K13Q,K17Q aa)
• pht1-4KR(K6R,K8R,K13R,K17R aa)
• pht1-deltaN(find)
• pht1delta
• pof3delta
• rna14-A394E(aa)
• swr1delta
• zfs1delta

FYPO:0007549 - coalescence of partially separated nuclei

References:

• PMID:32502403

Genes:

• apq12 (SPBC428.04)
• imp1 (SPBC1604.08c)

Genotypes:

• apq12delta
• imp1delta

FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

References:

• PMID:11069763
• PMID:11238999
• PMID:12455694
• PMID:12535531
• PMID:12719471
• PMID:16478992
• PMID:17442892
• PMID:17627824
• PMID:18158900
• PMID:19217403
• PMID:20739936
• PMID:22711988
• PMID:22792081
• PMID:24239120
• PMID:24774534
• PMID:25375240
• PMID:2544298
• PMID:27697865
• PMID:28567704
• PMID:29162938
• PMID:30155942
• PMID:32341083
• PMID:7628693
• PMID:8887647
• PMID:9182666

Genes:

• ams2 (SPCC290.04)
• ark1 (SPCC320.13c)
• asp1 (SPCC1672.06c)
• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)
• cid14 (SPAC12G12.13c)
• crb2 (SPBC342.05)
• csm1 (SPAC11E3.03)
• ctf1 (SPBC3B9.11c)
• cwf15 (SPBC337.06c)
• dam1 (SPAC589.08c)
• dhp1 (SPAC26A3.12c)
• dim1 (SPCC16A11.05c)
• dis1 (SPCC736.14)
• dis2 (SPBC776.02c)
• klp6 (SPBC1685.15c)
• mal2 (SPAC25B8.14)
• mcl1 (SPAPB1E7.02c)
• mcm4 (SPCC16A11.17)
• mde4 (SPBC6B1.04)
• mis19 (SPBC27B12.02)
• mph1 (SPBC106.01)
• scm3 (SPAPB1A10.02)
• sfh1 (SPCC16A11.14)
• sim3 (SPBC577.15c)
• sim4 (SPBC18E5.03c)
• sos7 (SPAPB17E12.06)
• spc7 (SPCC1020.02)

Genotypes:

• ams2::ura4[Null]
• ark1-T7(unknown)
• asp1-D333A(aa)
• cdc21-M68(unknown)
• chp1delta
• cid14delta
• crb2-2AQ(T73A,S80A aa)
• crb2delta
• csm1delta
• csp10-439(unknown)
• ctf1delta
• cwf15-32(unknown)
• dam1delta
• dhp1delta867-991(aa)
• dim1-35(G126D aa)
• dis1delta
• dis2-11(R245Q aa)
• kis1-1(R65C aa)
• klp6delta
• mal2-1(E277K aa)
• mal2delta
• mcl1-1(W109*)
• mcm4-tstd(Ub-DHFRts-mcm4)
• mde4delta
• mis19-1(F32I aa)
• mph1delta
• scm3-19(N50S aa)
• scm3-6(N100S aa)
• sfh1-13(E225D,K254E,P292Q aa)
• sim3-143(G81E aa)
• sim3-205(E207K aa)
• sim3delta
• sim4-193(unknown)
• sos7-+6(K264KIMRRYR)
• sos7-178(I178N aa)
• spc7-23(T3887G,G4079T nt)
• spc7-24(unknown)
• spc7-30(unknown)

FYPO:0005739 - complete but unequal mitotic sister chromatid segregation with unseparated chromosomes

References:

• PMID:11792803
• PMID:30635402

Genes:

• ark1 (SPCC320.13c)
• cka1 (SPAC23C11.11)

Genotypes:

• ark1delta
• cka1-372(H152Y aa)

FYPO:0000229 - cut

References:

• PMID:10341216
• PMID:10409743
• PMID:10588638
• PMID:10648611
• PMID:10683155
• PMID:10749926
• PMID:10835372
• PMID:11058134
• PMID:11402029
• PMID:11553781
• PMID:11715017
• PMID:11861551
• PMID:12135745
• PMID:14585996
• PMID:14739927
• PMID:15075270
• PMID:15116432
• PMID:15347659
• PMID:15647375
• PMID:16199877
• PMID:17189249
• PMID:17304223
• PMID:18180284
• PMID:22970243
• PMID:26746798
• PMID:27098497
• PMID:28775153
• PMID:30076928
• PMID:30810475
• PMID:30973898
• PMID:31332096
• PMID:32341083
• PMID:3283148
• PMID:35783577
• PMID:36695178
• PMID:38482739
• PMID:38780300
• PMID:39473973
• PMID:39652606
• PMID:7621824
• PMID:7723827
• PMID:7957098
• PMID:8552194
• PMID:9111307
• PMID:9115279
• PMID:9348105
• PMID:9531532
• PMID:9560390
• PMID:9601094
• PMID:9763447
• PMID:9832516
• PMID:9862966
• PMID:9864354
• PMID:9928931
• PMID:9950674

Genes:

• alp21 (SPAC22H10.10)
• ark1 (SPCC320.13c)
• ase1 (SPAPB1A10.09)
• bir1 (SPCC962.02c)
• bub1 (SPCC1322.12c)
• cbf11 (SPCC736.08)
• cdc2 (SPBC11B10.09)
• cdc6 (SPBC336.04)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• crb2 (SPBC342.05)
• cut11 (SPAC1786.03)
• cut12 (SPBC649.05)
• cut3 (SPBC146.03c)
• cut4 (SPBC106.09)
• cut8 (SPAC17C9.13c)
• dfp1 (SPCC550.13)
• gtb1 (SPBC32F12.04)
• hpz1 (SPBC2A9.07c)
• hsk1 (SPBC776.12c)
• hus1 (SPAC20G4.04c)
• kap113 (SPCC1322.06)
• liz1 (SPBC2G2.01c)
• mad2 (SPBC20F10.06)
• mcm4 (SPCC16A11.17)
• mep33 (SPBC28F2.02)
• mga2 (SPAC26H5.05)
• mph1 (SPBC106.01)
• mrc1 (SPAC694.06c)
• nse3 (SPCC645.04)
• nuc2 (SPAC17C9.01c)
• nup132 (SPAC1805.04)
• nup40 (SPAC19E9.01c)
• nup61 (SPCC18B5.07c)
• orc2 (SPBC685.09)
• pch1 (SPBC32F12.06)
• pic1 (SPBC336.15)
• pka1 (SPBC106.10)
• prp16 (SPBC1711.17)
• psf2 (SPBC725.13c)
• psm3 (SPAC10F6.09c)
• ptp4 (SPBC3D6.05)
• rad1 (SPAC1952.07)
• rad17 (SPAC14C4.13)
• rad24 (SPAC8E11.02c)
• rad3 (SPBC216.05)
• rad4 (SPAC23C4.18c)
• rad9 (SPAC664.07c)
• rfc2 (SPAC23D3.02)
• rfc3 (SPAC27E2.10c)
• rna14 (SPAC6F12.17)
• rpa2 (SPBP23A10.07)
• rqh1 (SPAC2G11.12)
• smc6 (SPCC5E4.06)
• ssb1 (SPBC660.13c)
• tel2 (SPAC458.03)
• ump1 (SPCC14G10.03c)
• wdr70 (SPAC343.17c)

Genotypes:

• alp21delta
• ark1delta
• ase1delta
• bir1-46(C976T aa)
• bub1delta
• cbf11(DBM)(R318H aa)
• cbf11delta
• cdc2-3w(C67Y aa)
• cdc6-ts3(R1064Q aa)
• cds1-FHA(S78A,H81A aa)
• cds1::ura4(disruption)[Null]
• cds1delta
• chk1-S345A(aa)
• chk1delta
• crb2delta
• crb2deltaC(547-778 Δaa)
• crb2deltaC1-607(608-778 Δaa)[Overexpression]
• cut11-2(C525R aa)
• cut11delta
• cut12-2(unknown)
• cut3-477(S1147P aa)
• cut4-533(unknown)
• cut5-T401(unknown)
• cut8-563(S201P aa)
• gtb1-93(P302L aa)
• him1-3A(S183A,T187A,T191A aa)
• him1-delta154-222(aa)
• him1-delta177-222(aa)
• hpz1delta
• hsk1::ura4+
• hus1delta
• kap113delta
• liz1-(unknown)
• liz1delta
• mad2delta
• mcm4-tstd(Ub-DHFRts-mcm4)
• mep33delta
• mga2delta
• mph1delta
• mrc1delta
• nse3-R254E(aa)
• nuc2-663(G504D aa)
• nup132delta
• nup40delta
• nup61delta
• orc2delta
• pch1delta
• pic1delta
• pka1delta
• prp16-F528S(aa)
• psf2delta
• psm3-304(unknown)
• ptp4delta
• rad1-1(unknown)
• rad17-d14(R411W aa)
• rad1delta
• rad24delta
• rad3-136(unknown)
• rad3delta
• rad9-S4(C144A,K145A,G147A,V148A,K150A,T151A aa)
• rad9delta
• rfc2delta
• rfc3-1(R216W aa)
• rna14-A394E(aa)
• rpa2-G1143D(aa)
• rqh1delta
• smc6-X(R706C aa)
• ssb1-R339H(aa)
• tel2-C307Y(aa)
• ump1delta
• wdr70delta

FYPO:0004592 - cut following normal mitosis

References:

• PMID:37288768

Genes:

• cbf11 (SPCC736.08)

Genotypes:

• cbf11delta

FYPO:0001055 - cut following normal mitotic chromosome condensation

References:

• PMID:10462526
• PMID:10526233
• PMID:11084332
• PMID:11279037
• PMID:12186944
• PMID:15507118
• PMID:17486116
• PMID:2203537
• PMID:8978688

Genes:

• cut1 (SPCC5E4.04)
• cut2 (SPBC14C8.01c)
• cut20 (SPAC19G12.01c)
• cut23 (SPAC6F12.14)
• cut8 (SPAC17C9.13c)
• mad2 (SPBC20F10.06)
• msd1 (SPBC13E7.06)
• ubc11 (SPCC1259.15c)
• zfs1 (SPBC1718.07c)

Genotypes:

• cut1-119(unknown)
• cut1-206(L739C aa)
• cut1delta
• cut2-364(R262*)
• cut20-100(unknown)
• cut23-194(unknown)
• cut8-563(S201P aa)
• mad2delta
• msd1delta
• ubcP4-140(unknown)
• zfs1delta

FYPO:0003165 - cut with abnormal chromosome segregation

References:

• PMID:10077566
• PMID:10082519
• PMID:10101168
• PMID:10409743
• PMID:10468581
• PMID:10497270
• PMID:10523629
• PMID:10567589
• PMID:10571085
• PMID:10756203
• PMID:10766248
• PMID:10779336
• PMID:10794172
• PMID:10835372
• PMID:10923022
• PMID:11027257
• PMID:11030343
• PMID:11080156
• PMID:11084332
• PMID:11134033
• PMID:11160827
• PMID:11359920
• PMID:11402029
• PMID:11432827
• PMID:11581276
• PMID:11598020
• PMID:11685532
• PMID:11715016
• PMID:11861551
• PMID:11937031
• PMID:11950927
• PMID:11971984
• PMID:12000964
• PMID:12006645
• PMID:12186947
• PMID:12455694
• PMID:12715160
• PMID:12724408
• PMID:12857865
• PMID:12966087
• PMID:1361173
• PMID:1427071
• PMID:14508607
• PMID:15147872
• PMID:15161942
• PMID:15314153
• PMID:15329725
• PMID:15466421
• PMID:15471884
• PMID:15507118
• PMID:15647375
• PMID:15743824
• PMID:15937127
• PMID:15957215
• PMID:16079915
• PMID:16453724
• PMID:16483313
• PMID:16738311
• PMID:16775007
• PMID:16950791
• PMID:17531813
• PMID:18180284
• PMID:18414064
• PMID:19101542
• PMID:19205745
• PMID:19487457
• PMID:19570910
• PMID:19750219
• PMID:21540296
• PMID:22645654
• PMID:22792081
• PMID:23071723
• PMID:23442800
• PMID:23697806
• PMID:23986474
• PMID:2406029
• PMID:24920823
• PMID:25487150
• PMID:25533348
• PMID:25552606
• PMID:25669599
• PMID:26366556
• PMID:26446992
• PMID:26746798
• PMID:27687771
• PMID:29162938
• PMID:29931271
• PMID:31615333
• PMID:32341083
• PMID:33506191
• PMID:35320724
• PMID:36695178
• PMID:38482739
• PMID:38780300
• PMID:6090122
• PMID:7622618
• PMID:7723827
• PMID:7798319
• PMID:7865880
• PMID:7916658
• PMID:7957061
• PMID:8065367
• PMID:8313888
• PMID:8343962
• PMID:8395535
• PMID:8537450
• PMID:8618924
• PMID:8682866
• PMID:8769419
• PMID:8895665
• PMID:8918880
• PMID:8972853
• PMID:9092625
• PMID:9111307
• PMID:9135148
• PMID:9153313
• PMID:9154809
• PMID:9154838
• PMID:9182666
• PMID:9184215
• PMID:9312055
• PMID:9348105
• PMID:9356477
• PMID:9566891
• PMID:9649518
• PMID:9658169
• PMID:9693370
• PMID:9705352
• PMID:9763441
• PMID:9832516
• PMID:9928931

Genes:

• alp1 (SPBC11C11.04c)
• alp13 (SPAC23H4.12)
• alp14 (SPCC895.07)
• alp4 (SPBC365.15)
• alp6 (SPBC428.20c)
• alp7 (SPAC890.02c)
• ark1 (SPCC320.13c)
• ase1 (SPAPB1A10.09)
• bir1 (SPCC962.02c)
• byr4 (SPAC222.10c)
• cbf11 (SPCC736.08)
• cbf12 (SPCC1223.13)
• cdc10 (SPBC336.12c)
• cdc18 (SPBC14C8.07c)
• cdc2 (SPBC11B10.09)
• cdc20 (SPBC25H2.13c)
• cdc22 (SPAC1F7.05)
• cdc25 (SPAC24H6.05)
• cdc31 (SPCC1682.04)
• cdc48 (SPAC1565.08)
• cds1 (SPCC18B5.11c)
• cdt1 (SPBC428.18)
• cdt2 (SPAC17H9.19c)
• chk1 (SPCC1259.13)
• cid12 (SPCC663.12)
• cnd2 (SPCC306.03c)
• crb2 (SPBC342.05)
• ctr4 (SPCC1393.10)
• cut1 (SPCC5E4.04)
• cut11 (SPAC1786.03)
• cut12 (SPBC649.05)
• cut14 (SPBP4H10.06c)
• cut15 (SPCC962.03c)
• cut2 (SPBC14C8.01c)
• cut20 (SPAC19G12.01c)
• cut3 (SPBC146.03c)
• cut4 (SPBC106.09)
• cut6 (SPAC56E4.04c)
• cut7 (SPAC25G10.07c)
• cut8 (SPAC17C9.13c)
• cut9 (SPAC6F12.15c)
• cwf15 (SPBC337.06c)
• dam1 (SPAC589.08c)
• ddb1 (SPAC17H9.10c)
• dfp1 (SPCC550.13)
• did4 (SPAC4F8.01)
• dim1 (SPCC16A11.05c)
• drc1 (SPAC6B12.11)
• efr3 (SPCC794.08)
• ers1 (SPCC1393.05)
• eso1 (SPBC16A3.11)
• fas2 (SPAC4A8.11c)
• hcn1 (SPAC23C11.12)
• hrp1 (SPAC1783.05)
• hsk1 (SPBC776.12c)
• hus1 (SPAC20G4.04c)
• hus5 (SPAC30D11.13)
• int6 (SPBC646.09c)
• lem2 (SPAC18G6.10)
• mcl1 (SPAPB1E7.02c)
• mcm4 (SPCC16A11.17)
• mde4 (SPBC6B1.04)
• mik1 (SPBC660.14)
• mis4 (SPAC31A2.05c)
• mrc1 (SPAC694.06c)
• nbl1 (SPBC725.12)
• nbs1 (SPBC6B1.09c)
• nda3 (SPBC26H8.07c)
• nrm1 (SPBC16A3.07c)
• nse1 (SPCC550.05)
• nse2 (SPAC16A10.06c)
• nse3 (SPCC645.04)
• nse5 (SPBC651.10)
• nse6 (SPAC11E3.08c)
• nuc2 (SPAC17C9.01c)
• nuf2 (SPAC27F1.04c)
• nup132 (SPAC1805.04)
• nup40 (SPAC19E9.01c)
• nur1 (SPCC4G3.11)
• orc1 (SPBC29A10.15)
• orc4 (SPBP23A10.13)
• orc5 (SPBC646.14c)
• pab1 (SPAC227.07c)
• par1 (SPCC188.02)
• pcn1 (SPBC16D10.09)
• pds5 (SPAC110.02)
• pfs2 (SPAC12G12.14c)
• plb1 (SPAC1A6.04c)
• plo1 (SPAC23C11.16)
• pmt3 (SPBC365.06)
• pol1 (SPAC3H5.06c)
• ppc89 (SPAC4H3.11c)
• prp2 (SPBC146.07)
• psm3 (SPAC10F6.09c)
• ptp4 (SPBC3D6.05)
• rad1 (SPAC1952.07)
• rad17 (SPAC14C4.13)
• rad21 (SPCC338.17c)
• rad26 (SPAC9E9.08)
• rad3 (SPBC216.05)
• rad31 (SPAC4C5.04)
• rad4 (SPAC23C4.18c)
• rad50 (SPAC1556.01c)
• rad60 (SPBC1921.02)
• rad9 (SPAC664.07c)
• rfc3 (SPAC27E2.10c)
• rqh1 (SPAC2G11.12)
• skp1 (SPBC409.05)
• sld3 (SPAC24H6.06)
• smc6 (SPCC5E4.06)
• spc34 (SPAC8C9.17c)
• spp1 (SPAC6B12.10c)
• spp2 (SPBC17D11.06)
• ssb1 (SPBC660.13c)
• ssb3 (SPCC23B6.05c)
• swi1 (SPBC216.06c)
• top2 (SPBC1A4.03c)
• top3 (SPBC16G5.12c)
• ubc11 (SPCC1259.15c)
• ubc4 (SPBC119.02)
• ubr1 (SPBC19C7.02)
• utp16 (SPBP8B7.10c)
• vps24 (SPAC9E9.14)

Genotypes:

• alp13-1837(unknown)
• alp14delta
• alp4-1891(unknown)
• alp4-225(unknown)
• alp6-719(unknown)
• alp7-738(unknown)
• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• ark1::his3+
• ase1delta
• bir1+(wild type)[Overexpression]
• bir1-1(T194A aa)
• bir1delta
• byr4delta
• cbf11+(wild type)[Overexpression]
• cbf11delta
• cbf12+(wild type)[Overexpression]
• cdc10-2E(S720E,T723E aa)
• cdc18-15(R172A,E173A aa)
• cdc18-16(E175A,K176A aa)
• cdc18-17(E180A,R184A aa)
• cdc18-25(E265A,E267A aa)
• cdc18-37(D418A,R420A,K421A aa)
• cdc18-46(E521A,D524A aa)
• cdc18-47(R536A,R538A,K540A aa)
• cdc18-51(K571A,R572A aa)
• cdc18-55(F303A,E304A,W305A aa)
• cdc18-56(N320A,D323A aa)
• cdc18-57(Y347A,T348A aa)
• cdc18-58(Q479A,Q480A,K481A aa)
• cdc18-DEAD(DE286AA aa)
• cdc18-K205A(aa)
• cdc18-ts1(G193D aa)
• cdc18delta
• cdc2-3w(C67Y aa)
• cdc2-4w(C67F aa)
• cdc20-P7(unknown)
• cdc21-M68(unknown)
• cdc22-M45(unknown)
• cdc25+(wild type)[Overexpression]
• cdc25-22(C532Y aa)
• cdc25-9A(S99A,S148A,S178A,S192A,S204A,S206A,T226A,S234A,S359A aa)
• cdc31-E147K(aa)[Knockdown]
• cdc48-353(G332D aa)
• cdc48-353(G332D aa)[Overexpression]
• cdc48-353sup(E319A,G332D aa)[Overexpression]
• cds1delta
• cdt1+(wild type)[Knockdown]
• cdt1delta
• cdt2delta
• chk1-1(E92D aa)
• chk1delta
• cid12delta
• cnd2-1(A114T aa)
• crb2-1(C1789T nt)
• crb2-2AQ(T73A,S80A aa)
• crb2delta
• ctr4delta
• cut1-206(L739C aa)
• cut1-380(unknown)
• cut1-474(R977Q,G1042D aa)
• cut1-513(E908G aa)
• cut1-514(unknown)
• cut1-645(unknown)
• cut1-679(G1674D aa)
• cut1-686(E1003K aa)
• cut1-693(A1816T aa)
• cut11-1(L521F aa)
• cut12-1(R536*)
• cut14+(wild type)[Knockdown]
• cut14-208(S861P aa)
• cut14-Y1(L543S aa)
• cut15-85(G419S,G450S aa)
• cut2(81-156)(1-75,152-196 Δaa)[Overexpression]
• cut2-364(R262*)
• cut2-447(L291S aa)
• cut2-EA2(D122A,E124A aa)
• cut2-ddm(R28A,L31A,R47A,L50A aa)[Overexpression]
• cut2-dm1(R28A,L31A aa)[Overexpression]
• cut2-dm2(R47A,L50A aa)[Overexpression]
• cut3-477(S1147P aa)
• cut4-533(unknown)
• cut5-401(unknown)
• cut5-580(unknown)
• cut6-621(unknown)
• cut7-123(L607S,K932E aa)
• cut7-138(unknown)
• cut7-22(P1021S aa)
• cut7-446(I954T aa)
• cut7-611(unknown)
• cut8-563(S201P aa)
• cut8delta
• cut9-234(unknown)
• cut9-41(S348P aa)
• cut9-665(A535T aa)
• cut9-98(unknown)
• cut9-T98(unknown)
• cwf15-32(unknown)
• dam1delta
• ddb1delta
• dfp1delta::ura4+(disruption)[Null]
• did4delta
• dim1-35(G126D aa)
• drc1+(wild type)[Knockdown]
• drc1-CD5A(T154A,T99A,T74A,T60A,S87A aa)
• efr3delta
• ers1delta
• eso1-G799D(aa)
• fas2-H518(I600N aa)
• hcn1+(wild type)[Knockdown]
• him1-Del5(1-103 Δaa)
• him1delta154-193(aa)
• hrp1+(wild type)[Overexpression]
• hsk1-1312(S314I aa)
• hsk1-89(L339P,E403K,L416P aa)
• hsk1-D216N(aa)[Overexpression]
• hsk1-T291E(aa)[Overexpression]
• hus1-14(unknown)
• hus1delta
• hus2-22(W789*)
• hus5.17(G253T nt)
• hus5.62(A129V aa)
• int6delta
• lem2delta
• lid1-6(unknown)
• mcl1-1(W109*)
• mcm4-tstd(Ub-DHFRts-mcm4)
• mde4delta
• mik1delta
• mis4-242(G1326E aa)
• mrc1-K235E,K236E(aa)
• mrc1delta
• mrc1delta221-284(aa)
• nbl1delta
• nbs1delta
• nda3-1828(unknown)
• nrm1delta
• nse1-1(unknown)
• nse2-1(unknown)
• nse3-R254E(aa)
• nse5delta
• nse6delta
• nuc2-663(G504D aa)
• nuf2-1(unknown)
• nuf2delta
• nup132delta
• nup40delta
• nur1delta
• orc1delta
• orc4+(wild type)[Overexpression]
• orc4delta
• orc4delta487-972(aa)[Overexpression]
• orc4deltaN(1-435 Δaa)[Overexpression]
• orc5-H19(V43A,C71R,Y177C,P191S,I352T aa)
• orc5-H37(L266P,P375L aa)
• orp1-4(unknown)
• pab1-R52A,V54A,F56A(aa)
• par1-G367V,K379A,V381A,F383A(aa)
• pcn1+(wild type)[Overexpression]
• pds5-1(pds5::ura4)
• pds5delta
• pfs2-11(unknown)
• plb1delta
• plo1-24c(unknown)
• pmt3delta
• pol1-1(unknown)
• pol1-D984N(aa)
• pol1-ts11(T840I aa)
• pol1-ts13(470-472 Δaa)
• pol1delta
• ppc89+(wild type)[Knockdown]
• ppc89+(wild type)[Overexpression]
• prp2-2(T259I aa)
• psm3-304(unknown)
• ptp4delta
• ptr11-1(G492S aa)
• rad1-h24(unknown)
• rad17-h11(unknown)
• rad17delta
• rad1delta
• rad21-K1(unknown)
• rad26.a14(C510CNPLIVC)
• rad26delta
• rad3-A2217V(aa)
• rad3-h1(unknown)
• rad31-1(unknown)
• rad31delta
• rad3delta
• rad4-42(T45A aa)
• rad50delta
• rad60delta
• rad9::ura4+
• rad9delta
• rfc3delta
• rhp9-64(unknown)
• rqh1+(wild type)[Overexpression]
• rqh1delta
• skp1-A2(V102A aa)
• skp1-A3(L113F aa)
• skp1-A4(unknown)
• skp1-A7(I110T aa)
• sld3-10(E338G aa)
• smc6-X(R706C aa)
• spc34delta
• spp1-14(unknown)
• spp1-21(unknown)
• spp1-4(unknown)
• spp1delta
• spp2-8(unknown)
• spp2-9(unknown)
• ssb1-R339H(aa)
• ssb1delta
• ssb3delta
• swi1-111(unknown)
• swi7-1(G1116E aa)
• swi7-H4(unknown)
• top2-110(unknown)
• top2-137(unknown)
• top2-175(unknown)
• top2-191(unknown)
• top2-3423(unknown)
• top2-4(unknown)
• top2-437(unknown)
• top2-640(unknown)
• top3-105(unknown)
• top3delta
• tsm1-512(unknown)
• ubc11+(wild type)[Knockdown]
• ubc11-P93L(aa)
• ubc4+(wild type)[Overexpression]
• ubc4-delta1-87(aa)
• ubr1delta
• utp16delta
• vps24delta

FYPO:0007968 - cut with mitotic spindle microtubules protruding beyond spindle pole body

References:

• PMID:26031557

Genes:

• pkl1 (SPAC3A11.14c)

Genotypes:

• pkl1delta

FYPO:0006692 - cut with septum between unequally sized nuclei

References:

• PMID:10567589
• PMID:38825008

Genes:

• bqt4 (SPBC19C7.10)
• pmt3 (SPBC365.06)

Genotypes:

• bqt4-IDR(364-413)(GFP-364-413)[Overexpression]
• pmt3delta

FYPO:0001054 - cut, elongated cell

References:

• PMID:23349636
• PMID:25487150

Genes:

• pab1 (SPAC227.07c)
• par1 (SPCC188.02)
• pof3 (SPCC338.16)
• swi1 (SPBC216.06c)

Genotypes:

• pab1delta
• par1delta
• pof3delta
• swi1delta

FYPO:0001053 - cut, normal size cell

References:

• PMID:37200372
• PMID:8395535

Genes:

• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• cut15 (SPCC962.03c)
• ssb1 (SPBC660.13c)

Genotypes:

• cds1delta
• chk1delta
• cut15-85(G419S,G450S aa)
• ssb1-1(K33E,Y264H aa)
• ssb1-10(K421R,Y474N,T585I aa)

FYPO:0001052 - cut, small cell

References:

• PMID:2682257
• PMID:33823662
• PMID:37200372
• PMID:8437586

Genes:

• cdc2 (SPBC11B10.09)
• rad3 (SPBC216.05)
• rna14 (SPAC6F12.17)

Genotypes:

• cdc2+(wild type)[Overexpression]
• cdc2-Y15F(aa)
• rad3delta
• rna14-393(L271P aa)

FYPO:0003286 - decreased mitotic chromosome condensation

References:

• PMID:10756203
• PMID:11554922
• PMID:11861551
• PMID:23263988
• PMID:26869222
• PMID:28545058
• PMID:7957061
• PMID:8769419

Genes:

• ark1 (SPCC320.13c)
• bir1 (SPCC962.02c)
• cdc20 (SPBC25H2.13c)
• cnd1 (SPBC776.13)
• cnd2 (SPCC306.03c)
• cnd3 (SPCC188.03)
• cut14 (SPBP4H10.06c)
• cut3 (SPBC146.03c)
• fas2 (SPAC4A8.11c)
• fbh1 (SPBC336.01)
• hrp1 (SPAC1783.05)
• rae1 (SPBC16A3.05c)
• top2 (SPBC1A4.03c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• bir1-1(T194A aa)
• cnd1-ae7(D368N aa)
• cnd2-ae9(L103P aa)
• cnd2-s1(S85F aa)
• cnd3-j29(R205Q aa)
• cut14-208(S861P aa)
• cut14-aa14(T558L aa)
• cut14-r8(G10D aa)
• cut17-275(A990T aa)
• cut3-477(S1147P aa)[Knockdown]
• cut3-477(S1147P aa)
• cut3-l23(S1116P aa)
• cut3-m26(L289F aa)
• fas2-H518(I600N aa)
• fbh1-c18(D734N aa)
• fbh1delta
• hrp1+(wild type)[Overexpression]
• pol2-am7(S400F aa)
• rae1-167(unknown)
• top2-191(unknown)

FYPO:0000415 - decreased mitotic sister chromatid segregation

References:

• PMID:12376568
• PMID:40193710

Genes:

• ned1 (SPAC1952.13)
• phi1 (SPAC9G1.08c)

Genotypes:

• ned1-1(G402D aa)/ned1-1(G402D aa)
• phi1delta

FYPO:0003268 - decreased rate of mitotic spindle elongation

References:

• PMID:15126629
• PMID:19686686
• PMID:23087209
• PMID:28178520
• PMID:30806623
• PMID:31089172
• PMID:37288768

Genes:

• cbf11 (SPCC736.08)
• clp1 (SPAC1782.09c)
• klp2 (SPAC664.10)
• klp9 (SPBC15D4.01c)
• scn1 (SPATRNAALA.03)
• wee1 (SPCC18B5.03)

Genotypes:

• cbf11delta
• clp1-C286S(aa)
• clp1-off(unknown)
• klp2-2A(S113A,S123A aa)
• klp9-2(K333M aa)
• klp9-G296A(aa)
• klp9delta
• scn1-17(C35T nt)
• wee1-50(G850E aa)

FYPO:0005343 - decreased rate of mitotic spindle elongation during anaphase B

References:

• PMID:14742702
• PMID:19686686
• PMID:25778919
• PMID:28178520
• PMID:28513584
• PMID:30806623
• PMID:31089172
• PMID:34080538
• PMID:9802907

Genes:

• alp7 (SPAC890.02c)
• ark1 (SPCC320.13c)
• ase1 (SPAPB1A10.09)
• clp1 (SPAC1782.09c)
• cut7 (SPAC25G10.07c)
• dis1 (SPCC736.14)
• klp9 (SPBC15D4.01c)
• top2 (SPBC1A4.03c)

Genotypes:

• alp7-738(unknown)
• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• ase1+(wild type)[Overexpression]
• ase1-S640D,S683D,S688D,S693D(aa)
• clp1delta
• cut7-122(M134T,T290K aa)
• dis1delta
• klp9-G296A(aa)
• klp9-S596D,S598D,S605D,S611D(aa)
• klp9-delta133C(500-633 Δaa)
• klp9-delta172C(461-633 Δaa)
• klp9-delta234C(399-633 Δaa)
• klp9-delta92C(541-633 Δaa)
• klp9-deltamotor(1-399 Δaa)
• klp9-md(GKT99AAA aa)
• klp9delta
• top2-191(unknown)

FYPO:0007960 - decreased rate of mitotic spindle elongation during prophase

References:

• PMID:24239120

Genes:

• ase1 (SPAPB1A10.09)

Genotypes:

• ase1delta

FYPO:0006559 - delayed onset of mitotic spindle disassembly

References:

• PMID:22573890
• PMID:32848252

Genes:

• cyk3 (SPAC9G1.06c)
• imp1 (SPBC1604.08c)

Genotypes:

• cyk3delta
• imp1delta

FYPO:0002636 - delayed onset of mitotic spindle elongation

References:

• PMID:19523829
• PMID:22065639
• PMID:22134091
• PMID:23087209
• PMID:24963130
• PMID:9852154

Genes:

• csm1 (SPAC11E3.03)
• kms2 (SPBC947.12)
• mal3 (SPAC18G6.15)
• mde4 (SPBC6B1.04)
• nsk1 (SPAC3G9.01)
• plo1 (SPAC23C11.16)
• sid2 (SPAC24B11.11c)

Genotypes:

• csm1delta
• kms2+(wild type)[Knockdown]
• mal3-S147E,S151E(aa)
• mal3-S147E(aa)
• mde4-12A(S147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401A aa)
• mde4delta
• nsk1delta
• plo1-24c(unknown)
• plo1-25(unknown)
• sid2-250(E314K aa)

FYPO:0006049 - fluctuating mitotic spindle length

References:

• PMID:27146110

Genes:

• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)

Genotypes:

• klp5delta
• klp6delta

FYPO:0003757 - incomplete mitotic sister chromatid segregation

References:

• PMID:11554922

Genes:

• bir1 (SPCC962.02c)

Genotypes:

• cut17-275(A990T aa)

FYPO:0003970 - incomplete mitotic sister chromatid segregation, with chromatin bridge

References:

• PMID:12455694
• PMID:15507118
• PMID:21540296
• PMID:21633354
• PMID:30635289
• PMID:7957061

Genes:

• ark1 (SPCC320.13c)
• cnd2 (SPCC306.03c)
• cut3 (SPBC146.03c)
• mcl1 (SPAPB1E7.02c)
• nrm1 (SPBC16A3.07c)
• res2 (SPAC22F3.09c)
• taz1 (SPAC16A10.07c)
• top3 (SPBC16G5.12c)
• yox1 (SPBC21B10.13c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• cnd2-2A-1(S5A,S41A aa)
• cnd2-2A-2(S5A,S52A aa)
• cnd2-2A-3(S41A,S52A aa)
• cnd2-2E-1(S5E,S41E aa)
• cnd2-2E-3(S41E,S52E aa)
• cnd2-3E(S5E,S41E,S52E aa)
• cut3-477(S1147P aa)
• mcl1-1(W109*)
• nrm1delta
• res2delta
• taz1delta
• top3-105(unknown)
• yox1delta

FYPO:0004098 - incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass

References:

• PMID:21540296
• PMID:7957061

Genes:

• ark1 (SPCC320.13c)
• cut14 (SPBP4H10.06c)

Genotypes:

• ark1-as3(L166A,S229A,Q28R,Q176R aa)
• cut14-208(S861P aa)

FYPO:0001271 - incomplete, unequal mitotic sister chromatid segregation

References:

• PMID:11069763
• PMID:15371542
• PMID:22711988

Genes:

• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)
• sos7 (SPAPB17E12.06)
• spc7 (SPCC1020.02)

Genotypes:

• chp1delta
• csp10-439(unknown)
• sos7-+6(K264KIMRRYR)
• sos7-delta7(Y258*)
• spc7-C(unknown)[Overexpression]

FYPO:0001272 - incomplete, unequal mitotic sister chromatid segregation, with smeared DNA

References:

• PMID:10341216
• PMID:17442892
• PMID:7957061
• PMID:9024682

Genes:

• alp21 (SPAC22H10.10)
• cbp1 (SPBC1105.04c)
• cut3 (SPBC146.03c)
• spc7 (SPCC1020.02)

Genotypes:

• alp21delta
• cbp1delta
• cut3-477(S1147P aa)
• spc7-23(T3887G,G4079T nt)

FYPO:0007958 - increased rate of mitotic spindle elongation

References:

• PMID:30806623

Genes:

• cdc25 (SPAC24H6.05)
• klp9 (SPBC15D4.01c)

Genotypes:

• cdc25-22(C532Y aa)
• klp9+(wild type)[Overexpression]

FYPO:0007071 - increased rate of mitotic spindle elongation during anaphase A

References:

• PMID:31427431

Genes:

• dis1 (SPCC736.14)
• klp5 (SPBC2F12.13)

Genotypes:

• dis1delta
• klp5delta

FYPO:0005976 - increased rate of mitotic spindle elongation during anaphase B

References:

• PMID:27697865
• PMID:27872152

Genes:

• asp1 (SPCC1672.06c)
• dis1 (SPCC736.14)

Genotypes:

• asp1-D333A(aa)
• dis1-LAPA(L841A,P844A aa)

FYPO:0007959 - increased rate of mitotic spindle elongation during prophase

References:

• PMID:24239120

Genes:

• klp6 (SPBC1685.15c)

Genotypes:

• klp6delta

FYPO:0003760 - inviable after spore germination, single or double cell division, arrest with cut

References:

• PMID:10523506
• PMID:10747036
• PMID:8537450
• PMID:8978688
• PMID:9693370

Genes:

• cut2 (SPBC14C8.01c)
• orc5 (SPBC646.14c)
• pol1 (SPAC3H5.06c)
• smc5 (SPAC14C4.02c)

Genotypes:

• cut2delta
• orc5::ura4+(nt246-993)(disruption)[Null]
• pol1-D984N(aa)[Knockdown]
• pol1-ts13(470-472 Δaa)
• pol1delta
• smc5delta

FYPO:0003843 - inviable following spore germination, single cell division, unequal chromosome segregation

References:

• PMID:10571085

Genes:

• bir1 (SPCC962.02c)

Genotypes:

• bir1delta

FYPO:0000228 - lagging mitotic chromosomes

References:

• PMID:10733588
• PMID:10749926
• PMID:10756203
• PMID:11780129
• PMID:11809834
• PMID:11967147
• PMID:12181326
• PMID:12376568
• PMID:12455694
• PMID:12482946
• PMID:12526748
• PMID:12535531
• PMID:12689592
• PMID:12719471
• PMID:15507118
• PMID:15509783
• PMID:15615848
• PMID:15908586
• PMID:15947136
• PMID:16079915
• PMID:16127433
• PMID:16199877
• PMID:16428807
• PMID:16738311
• PMID:16920624
• PMID:17614284
• PMID:17627824
• PMID:17677001
• PMID:17948055
• PMID:18158900
• PMID:18362178
• PMID:18493607
• PMID:18716626
• PMID:19217404
• PMID:19362535
• PMID:19523829
• PMID:19758558
• PMID:19965387
• PMID:20018856
• PMID:20211136
• PMID:20739936
• PMID:20929775
• PMID:21270388
• PMID:21633354
• PMID:22065639
• PMID:22264609
• PMID:22268381
• PMID:22281223
• PMID:22895252
• PMID:23050226
• PMID:23427262
• PMID:23885124
• PMID:25057016
• PMID:25253718
• PMID:25472718
• PMID:25543137
• PMID:27304859
• PMID:27666591
• PMID:27697865
• PMID:28231281
• PMID:28974540
• PMID:29180432
• PMID:29844133
• PMID:30635289
• PMID:30635402
• PMID:31000521
• PMID:31427431
• PMID:31895039
• PMID:35194019
• PMID:36537249
• PMID:39378339
• PMID:39916665
• PMID:40193710
• PMID:7660126
• PMID:8937982
• PMID:9722643
• PMID:9864354

Genes:

• acr1 (SPBC17D1.04)
• ago1 (SPCC736.11)
• alm1 (SPAC1486.04c)
• alp7 (SPAC890.02c)
• ams2 (SPCC290.04)
• ark1 (SPCC320.13c)
• asp1 (SPCC1672.06c)
• bir1 (SPCC962.02c)
• bub1 (SPCC1322.12c)
• bub3 (SPAC23H3.08c)
• cbp1 (SPBC1105.04c)
• ccp1 (SPBC36B7.08c)
• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)
• clr4 (SPBC428.08c)
• clr6 (SPBC36.05c)
• cnd2 (SPCC306.03c)
• cnp3 (SPBC1861.01c)
• csi1 (SPBC2G2.14)
• csi2 (SPAC4D7.07c)
• csm1 (SPAC11E3.03)
• cul4 (SPAC3A11.08)
• dam1 (SPAC589.08c)
• dbl2 (SPCC553.01c)
• dcr1 (SPCC188.13c)
• ddb1 (SPAC17H9.10c)
• dis1 (SPCC736.14)
• dsh1 (SPBC582.04c)
• elf1 (SPAC3C7.08c)
• epe1 (SPCC622.16c)
• eso1 (SPBC16A3.11)
• fas2 (SPAC4A8.11c)
• fta1 (SPAC4F10.12)
• gtb1 (SPBC32F12.04)
• hhf1 (SPAC1834.03c)
• hip1 (SPBC31F10.13c)
• hip3 (SPBC31F10.14c)
• hrk1 (SPAC23C4.03)
• hrp1 (SPAC1783.05)
• hrp3 (SPAC3G6.01)
• hsp104 (SPBC16D10.08c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mcl1 (SPAPB1E7.02c)
• mde4 (SPBC6B1.04)
• mhf2 (SPCC576.12c)
• mis4 (SPAC31A2.05c)
• mph1 (SPBC106.01)
• mts4 (SPBP19A11.03c)
• mzt1 (SPAC9G1.15c)
• ndc80 (SPBC11C11.03)
• ned1 (SPAC1952.13)
• nrm1 (SPBC16A3.07c)
• nsk1 (SPAC3G9.01)
• pds5 (SPAC110.02)
• phi1 (SPAC9G1.08c)
• pob3 (SPBC609.05)
• pof3 (SPCC338.16)
• prp16 (SPBC1711.17)
• psc3 (SPAC17H9.20)
• psf2 (SPBC725.13c)
• pst1 (SPBC12C2.10c)
• rdp1 (SPAC6F12.09)
• res2 (SPAC22F3.09c)
• rik1 (SPCC11E10.08)
• rpb2 (SPAC23G3.01)
• sal3 (SPCC1840.03)
• scm3 (SPAPB1A10.02)
• sgo2 (SPAC15A10.15)
• sim3 (SPBC577.15c)
• sim4 (SPBC18E5.03c)
• slm9 (SPBC15D4.03)
• snu4 (SPSNRNA.04)
• stc1 (SPBP8B7.28c)
• swi6 (SPAC664.01c)
• top2 (SPBC1A4.03c)
• wip1 (SPAC17G8.15)
• yox1 (SPBC21B10.13c)

Genotypes:

• acr1-936(unknown)
• ago1delta
• alm1delta
• alp7delta(307-312)(aa)
• ams2::ura4[Null]
• ark1-T7(unknown)
• asp1-D333A(aa)
• bir1-46(C976T aa)
• bub1-KD(K762R,D900N aa)
• bub1delta
• bub1delta/bub1delta
• bub3delta
• cbp1::ura4(disruption)
• ccp1delta
• chp1delta
• cid12-DADA(D77A,D79A aa)
• cid12delta
• clr4-S5(unknown)
• clr4delta
• clr4delta->clr4+(reintroduced clr4+)
• clr6-1(G269D aa)
• cnd2-3A(S5A,S41A,S52A aa)
• cnp3-T28E(aa)
• cnp3delta
• cos1-17(V233A aa)
• cos1-22(A574D aa)
• cos1-38(G622E aa)
• cos1-7(G242R aa)
• cos1-86(Q765*)
• csi1-I463N,P464N(aa)
• csi1delta
• csi2delta
• csm1delta
• cul4-1(marker gene insertion at 3'-UTR)
• cut17-275(A990T aa)
• dam1delta
• dbl2delta
• dcr1delta
• ddb1delta
• dis1-6A(T279A,S293A,S300A,S551A,S556A,S590A aa)
• dis1delta
• dsh1delta
• elf1delta
• epe1delta
• eso1-G799D(aa)
• fas2+(wild type)[Knockdown]
• fta1-ts(unknown)
• gtb1-93(P302L aa)
• hhf1+(wild type)[Overexpression]
• hip1delta
• hip3delta
• hrk1delta
• hrp1delta
• hrp3delta
• hsp104delta
• klp5-Q582P(aa)
• klp5delta
• klp6delta
• mcl1-1(W109*)
• mde4-12A(S147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401A aa)
• mde4delta
• mhf2delta
• mis4-242(G1326E aa)
• mis4-367(G1487D aa)
• mis4-450(L296F,P368L aa)
• mph1-deltaK(323-678 Δnt)
• mph1delta
• mts4-1(unknown)
• mzt1-T27W(aa)
• ndc80-NH12(F420S aa)
• ned1-1(G402D aa)
• nrm1delta
• nsk1-18A(S71A,S103A,S113A,S140A,S171A,S195A,S206A,S221A,S236A,T240A,T255A,S257A,S289A,S344A,S379A,S399A,T411A,T437A aa)
• pds5delta
• phi1delta
• pob3delta
• pof3delta
• prp13-1(G35A nt)
• prp16-2(Q140*)
• psc3-1T(unknown)
• psc3-407(T234I aa)
• psf2delta
• pst1-1(W1305*)
• rdp1-D903A(aa)
• res2delta
• rik1::LEU2(disruption)[Null]
• rpb2-m203(N44Y aa)
• sal3delta
• scm3-106(L73F aa)
• scm3-139(L56F aa)
• scm3-15(S281L aa)
• sgo2delta
• sim1-(unknown)
• sim3-143(G81E aa)
• sim3-205(E207K aa)
• sim4-193(unknown)
• slm9delta
• stc1delta
• swi6-115(W269R aa)
• swi6::his1(disruption)
• swi6delta
• top2-2A(S1363A,S1364A aa)
• wip1delta
• yox1delta

FYPO:0004101 - lagging mitotic chromosomes, with complete sister chromatid separation

References:

• PMID:11861551
• PMID:17561805
• PMID:17627824
• PMID:20624975
• PMID:24239120
• PMID:27146110
• PMID:28455357

Genes:

• ask1 (SPBC27.02c)
• bir1 (SPCC962.02c)
• csm1 (SPAC11E3.03)
• dam1 (SPAC589.08c)
• dcn1 (SPBC839.03c)
• dhc1 (SPAC1093.06c)
• klp5 (SPBC2F12.13)
• klp6 (SPBC1685.15c)
• mad2 (SPBC20F10.06)
• mde4 (SPBC6B1.04)

Genotypes:

• ask1delta
• bir1+(wild type)[Knockdown]
• bir1-1(T194A aa)
• csm1delta
• dam1delta
• dcn1delta
• dhc1delta
• klp5delta
• klp6delta
• mad2delta
• mde4delta

FYPO:0004382 - meroterically attached lagging mitotic chromosomes

References:

• PMID:19948483
• PMID:20739936
• PMID:20935472
• PMID:28343969

Genes:

• bir1 (SPCC962.02c)
• cdc13 (SPBC582.03)
• clr4 (SPBC428.08c)
• csm1 (SPAC11E3.03)
• hrk1 (SPAC23C4.03)
• pds5 (SPAC110.02)
• rad21 (SPCC338.17c)

Genotypes:

• bir1-8A(S202A,S229A,S244A,S278A,S294A,T393A,T831A,T908A aa)
• cdc13-117(C379Y aa)
• cdc13-M7(E255G aa)
• clr4delta
• csm1delta
• hrk1-pim(K8A,T9A,Y10A,G11A aa)
• pds5-him(P84A,D85A,P87A aa)
• rad21-K1(unknown)

FYPO:0003012 - mitosis with unreplicated DNA

References:

• PMID:12186947
• PMID:8631307
• PMID:9392077

Genes:

• mcm4 (SPCC16A11.17)
• orc1 (SPBC29A10.15)

Genotypes:

• mcm4delta
• orp1-4(unknown)

FYPO:0000283 - mitotic chromosome fragmentation upon segregation

References:

• PMID:16079915
• PMID:19915592
• PMID:21270388
• PMID:9092625
• PMID:9264467

Genes:

• cam1 (SPAC3A12.14)
• dam1 (SPAC589.08c)
• hus5 (SPAC30D11.13)
• pht1 (SPBC11B10.10c)
• rad31 (SPAC4C5.04)
• wip1 (SPAC17G8.15)

Genotypes:

• cam1-E14(E69V,E106V aa)
• dam1delta
• hus5.62(A129V aa)
• pht1delta
• rad31-1(unknown)
• rad31delta
• wip1delta

FYPO:0006475 - mitotic spindle collapse

References:

• PMID:27697865
• PMID:28178520
• PMID:32502403

Genes:

• ase1 (SPAPB1A10.09)
• asp1 (SPCC1672.06c)
• clp1 (SPAC1782.09c)

Genotypes:

• ase1delta
• asp1-D333A(aa)
• clp1-C286S(aa)

FYPO:0005722 - mitotic spindle collapse during anaphase B elongation

References:

• PMID:15147872
• PMID:15689489
• PMID:18562692
• PMID:31615768

Genes:

• ase1 (SPAPB1A10.09)
• skp1 (SPBC409.05)

Genotypes:

• ase1delta
• skp1-A7(I110T aa)

FYPO:0006172 - mitotic spindle collapse without elongation during anaphase B

References:

• PMID:25375240

Genes:

• mis19 (SPBC27B12.02)
• mis6 (SPAC1687.20c)

Genotypes:

• kis1-1(R65C aa)
• mis6-302(G135E aa)

FYPO:0006643 - mitotic spindle collapse without elongation during metaphase

References:

• PMID:18562692
• PMID:28178520

Genes:

• ase1 (SPAPB1A10.09)
• klp9 (SPBC15D4.01c)

Genotypes:

• ase1delta
• klp9delta

FYPO:0002688 - mitotic spindle collapse without elongation during prophase

References:

• PMID:15647375
• PMID:17380189
• PMID:18262494
• PMID:19523829
• PMID:19686686
• PMID:21256022
• PMID:23885124
• PMID:24963130

Genes:

• ase1 (SPAPB1A10.09)
• cut7 (SPAC25G10.07c)
• dam1 (SPAC589.08c)
• dis1 (SPCC736.14)
• dis3 (SPBC26H8.10)
• kms2 (SPBC947.12)
• mde4 (SPBC6B1.04)
• mzt1 (SPAC9G1.15c)
• ndc80 (SPBC11C11.03)

Genotypes:

• ase1delta
• cut7-24(V968A aa)
• dam1delta
• dis1delta
• dis3-54(P509L aa)
• kms2+(wild type)[Knockdown]
• mde4delta
• mzt1-E10P(aa)
• mzt1-T27W(aa)
• ndc80-21(T307A,E379G,L405P aa)

FYPO:0001273 - mitotic spindle elongation with incomplete, unequal mitotic sister chromatid segregation and unseparated DNA

References:

• PMID:22711988
• PMID:37288768
• PMID:8887647

Genes:

• cbf11 (SPCC736.08)
• mal2 (SPAC25B8.14)
• sos7 (SPAPB17E12.06)

Genotypes:

• cbf11delta
• mal2-1(E277K aa)
• mal2delta
• sos7-+6(K264KIMRRYR)
• sos7-178(I178N aa)
• sos7-delta7(Y258*)

FYPO:0003758 - mitotic spindle elongation without chromosome separation

References:

• PMID:11369198
• PMID:11792803
• PMID:12724408
• PMID:15371542
• PMID:15957215
• PMID:16453724
• PMID:16483313
• PMID:16855021
• PMID:2203537
• PMID:7774573
• PMID:7957061
• PMID:8395535
• PMID:8978687
• PMID:8978688
• PMID:9802907

Genes:

• alp14 (SPCC895.07)
• ark1 (SPCC320.13c)
• cdc2 (SPBC11B10.09)
• cut1 (SPCC5E4.04)
• cut14 (SPBP4H10.06c)
• cut15 (SPCC962.03c)
• cut2 (SPBC14C8.01c)
• dma1 (SPAC17G8.10c)
• fta2 (SPAC1783.03)
• spc7 (SPCC1020.02)
• top2 (SPBC1A4.03c)
• ubc4 (SPBC119.02)

Genotypes:

• alp14delta
• ark1delta
• cdc2-DL41(P162L aa)[Overexpression]
• cut1-206(L739C aa)
• cut1-K73(unknown)[Overexpression]
• cut14-208(S861P aa)
• cut15-85(G419S,G450S aa)
• cut2-364(R262*)
• dma1+(wild type)[Overexpression]
• fta2-291(G291S aa)
• fta2-292(F292L aa)
• spc7-C(unknown)[Overexpression]
• top2-191(unknown)
• ubc4-delta1-87(aa)

FYPO:0007859 - nuclear division in absence of mitotic spindle

References:

• PMID:20967237

Genes:

• cdc11 (SPCC1739.11c)
• nda3 (SPBC26H8.07c)

Genotypes:

• cdc11-119(unknown)
• nda3-KM311(G93E aa)

FYPO:0001046 - premature mitosis

References:

• PMID:12442907
• PMID:37787465
• PMID:7774573
• PMID:9034336
• PMID:9042863

Genes:

• cdc2 (SPBC11B10.09)
• cdc25 (SPAC24H6.05)
• efm2 (SPCC338.11c)
• map2 (SPCC1795.06)
• wis1 (SPBC409.07c)

Genotypes:

• cdc2-3w(C67Y aa)
• cdc2-DL50(240-242 Δnt)[Overexpression]
• cdc2-Y15F(aa)
• cdc25+(wild type)[Overexpression]
• efm2delta
• map2+(wild type)[Overexpression]
• wis1delta

FYPO:0007566 - premature mitotic chromosome condensation

References:

• PMID:12000964

Genes:

• cnd2 (SPCC306.03c)

Genotypes:

• cnd2-1(A114T aa)

FYPO:0005417 - premature mitotic spindle elongation

References:

• PMID:9802907

Genes:

• dis1 (SPCC736.14)

Genotypes:

• dis1-(unknown)

FYPO:0006524 - premature sister kinetochore separation during mitotic G2 phase

References:

• PMID:11598020

Genes:

• pds5 (SPAC110.02)

Genotypes:

• pds5-1(pds5::ura4)

FYPO:0007861 - sister chromatid separation during nuclear fission

References:

• PMID:20967237

Genes:

• cdc11 (SPCC1739.11c)

Genotypes:

• cdc11-119(unknown)

FYPO:0007860 - spindle pole body separation in absence of mitotic spindle

References:

• PMID:20967237

Genes:

• cdc11 (SPCC1739.11c)

Genotypes:

• cdc11-119(unknown)

FYPO:0003241 - unequal mitotic sister chromatid segregation

References:

• PMID:10398680
• PMID:10567589
• PMID:10588638
• PMID:10794172
• PMID:11359920
• PMID:11554922
• PMID:11861765
• PMID:12181326
• PMID:12242294
• PMID:12689592
• PMID:12773390
• PMID:14730319
• PMID:15502821
• PMID:15507118
• PMID:16079915
• PMID:16199877
• PMID:16394105
• PMID:16855021
• PMID:17004072
• PMID:17486116
• PMID:18262494
• PMID:18362178
• PMID:18493607
• PMID:19362535
• PMID:19680287
• PMID:19758558
• PMID:19942852
• PMID:21445296
• PMID:22264609
• PMID:23267073
• PMID:24497846
• PMID:25269894
• PMID:28475874
• PMID:28827290
• PMID:29194511
• PMID:30635289
• PMID:30973898
• PMID:31615768
• PMID:34849791
• PMID:35970865
• PMID:37052630
• PMID:38084929
• PMID:38166399
• PMID:39916665
• PMID:8247131
• PMID:8552194
• PMID:8887647
• PMID:9111307
• PMID:9264467
• PMID:9649518
• PMID:9808627

Genes:

• alp1 (SPBC11C11.04c)
• ani1 (SPBC1347.02)
• ani2 (SPAC27F1.06c)
• atb2 (SPBC800.05c)
• bir1 (SPCC962.02c)
• bub3 (SPAC23H3.08c)
• cam1 (SPAC3A12.14)
• cdc20 (SPBC25H2.13c)
• chp1 (SPAC18G6.02c)
• cnp1 (SPBC1105.17)
• cnp3 (SPBC1861.01c)
• csm1 (SPAC11E3.03)
• cut14 (SPBP4H10.06c)
• cut9 (SPAC6F12.15c)
• dad1 (SPAC16A10.05c)
• dam1 (SPAC589.08c)
• ddb1 (SPAC17H9.10c)
• drp1 (SPBC691.02c)
• ekc1 (SPCC663.01c)
• fta1 (SPAC4F10.12)
• fta2 (SPAC1783.03)
• hsk1 (SPBC776.12c)
• mal2 (SPAC25B8.14)
• mal3 (SPAC18G6.15)
• mcl1 (SPAPB1E7.02c)
• mde4 (SPBC6B1.04)
• mis12 (SPBC409.04c)
• mis13 (SPBC409.09c)
• mis16 (SPCC1672.10)
• mis17 (SPBC21.01)
• mis4 (SPAC31A2.05c)
• mis6 (SPAC1687.20c)
• msd1 (SPBC13E7.06)
• ndc80 (SPBC11C11.03)
• nrm1 (SPBC16A3.07c)
• nuc2 (SPAC17C9.01c)
• orc2 (SPBC685.09)
• pcp1 (SPAC6G9.06c)
• pds5 (SPAC110.02)
• peg1 (SPAC3G9.12)
• pka1 (SPBC106.10)
• pmt3 (SPBC365.06)
• ppe1 (SPCC1739.12)
• psc3 (SPAC17H9.20)
• psf2 (SPBC725.13c)
• rad21 (SPCC338.17c)
• rad52 (SPAC30D11.10)
• raf1 (SPCC613.12c)
• raf2 (SPCC970.07c)
• rfc3 (SPAC27E2.10c)
• rpt2 (SPBC4.07c)
• scm3 (SPAPB1A10.02)
• sgo2 (SPAC15A10.15)
• spc7 (SPCC1020.02)
• ssb1 (SPBC660.13c)
• wee1 (SPCC18B5.03)