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Phenotype ontology term - FYPO:0000643 - abnormal mitotic DNA integrity checkpoint

Term summary

ID
FYPO:0000643
Name
abnormal mitotic DNA integrity checkpoint
Ontology or CV name
Phenotype
Definition
A cell cycle checkpoint phenotype in which a mitotic DNA integrity checkpoint is abnormal. A DNA integrity checkpoint normally regulates cell cycle progression in response to changes in DNA structure. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

Annotation

Multi-locus phenotype

FYPO:0000173 - abnormal mitotic cell cycle DNA replication checkpoint

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FYPO:0002900 - abnormal mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0004359 - abolished mitotic cell cycle DNA replication checkpoint

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0004360 - decreased duration of mitotic cell cycle DNA replication checkpoint

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FYPO:0004870 - decreased duration of mitotic G2 DNA damage checkpoint

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FYPO:0007248 - decreased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0005094 - decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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FYPO:0003445 - increased duration of mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0005953 - increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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Single locus phenotype

FYPO:0000173 - abnormal mitotic cell cycle DNA replication checkpoint

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FYPO:0000006 - abnormal mitotic DNA damage checkpoint

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FYPO:0002900 - abnormal mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0004373 - abnormal mitotic G2 DNA damage checkpoint

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FYPO:0000007 - abnormal S-phase DNA damage checkpoint

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FYPO:0006436 - abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0004359 - abolished mitotic cell cycle DNA replication checkpoint

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0007247 - abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0003814 - abolished response to S-phase DNA damage checkpoint signaling

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FYPO:0004360 - decreased duration of mitotic cell cycle DNA replication checkpoint

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FYPO:0004870 - decreased duration of mitotic G2 DNA damage checkpoint

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FYPO:0004371 - decreased duration of S-phase DNA damage checkpoint

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FYPO:0005094 - decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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FYPO:0004781 - delayed onset of mitotic G2 DNA damage checkpoint

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FYPO:0008162 - increased activation of S-phase DNA damage checkpoint

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FYPO:0003545 - increased duration of mitotic cell cycle DNA replication checkpoint

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FYPO:0002341 - increased duration of mitotic DNA damage checkpoint

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FYPO:0003490 - increased duration of mitotic DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0005603 - increased duration of mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0003445 - increased duration of mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0005627 - increased duration of mitotic DNA damage checkpoint during cellular response to UV during mitotic S phase

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FYPO:0005953 - increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0001707 - increased mitotic DNA damage checkpoint activation

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