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Phenotype ontology term - FYPO:0000704 - abnormal protein-protein interaction

Term summary

ID
FYPO:0000704
Name
abnormal protein-protein interaction
Ontology or CV name
Phenotype
Definition
A molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes.

Parents

Annotation

Multi-locus phenotype

FYPO:0007597 - abolished CLRC complex binding

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0005784 - decreased extent and duration of protein-protein interaction

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0001571 - increased protein-protein interaction

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Single locus phenotype

FYPO:0000704 - abnormal protein-protein interaction

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FYPO:0003591 - abnormal protein complex binding

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FYPO:0006025 - abolished actin filament binding

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FYPO:0005861 - abolished CCR4-NOT complex binding

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FYPO:0007597 - abolished CLRC complex binding

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FYPO:0003247 - abolished histone H3 binding

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FYPO:0003431 - abolished histone H3K9me binding

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FYPO:0008187 - abolished histone H4 binding

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FYPO:0007884 - abolished Lsm2-8 complex binding

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FYPO:0005234 - abolished MCM complex binding

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FYPO:0004232 - abolished methylated histone binding

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FYPO:0005862 - abolished MTREC complex binding

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FYPO:0006799 - abolished nuclear MIS12/MIND complex binding

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FYPO:0004226 - abolished nucleosome binding

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0004335 - abolished protein-protein interaction during cellular response to hydrogen peroxide

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FYPO:0003425 - abolished protein-protein interaction during cellular response to rapamycin

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FYPO:0003297 - abolished ribosome binding

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FYPO:0006066 - abolished tubulin heterodimer binding

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FYPO:0003633 - abolished U1 snRNP binding

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FYPO:0003635 - abolished U2 snRNP binding

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FYPO:0005119 - altered protein binding specificity

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FYPO:0002656 - decreased actin filament binding

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FYPO:0010031 - decreased CCR4-NOT complex binding

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FYPO:0005785 - decreased duration of protein-protein interaction

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FYPO:0005784 - decreased extent and duration of protein-protein interaction

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FYPO:0007158 - decreased histone H3 binding

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FYPO:0008195 - decreased histone H3-K9Me binding

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FYPO:0007159 - decreased histone H4 binding

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FYPO:0008059 - decreased K48-linked polyubiquitin binding

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FYPO:0007885 - decreased Lsm2-8 complex binding

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FYPO:0006451 - decreased methylated histone binding

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FYPO:0007173 - decreased mitotic checkpoint complex binding

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FYPO:0004227 - decreased nucleosome binding

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FYPO:0005142 - decreased proteasome core complex binding

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0003207 - decreased protein-protein interaction during cellular response to hydrogen peroxide

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FYPO:0005294 - decreased protein-protein interaction during cellular response to hydroxyurea

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FYPO:0005293 - decreased protein-protein interaction during cellular response to methyl methanesulfonate

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FYPO:0003206 - decreased protein-protein interaction during cellular response to salt stress

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FYPO:0005546 - decreased protein-protein interaction during mitotic S phase

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FYPO:0010025 - decreased sumoylated protein-protein interaction

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FYPO:0003634 - decreased U1 snRNP binding

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FYPO:0003636 - decreased U2 snRNP binding

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FYPO:0007798 - increased actin filament binding

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FYPO:0003592 - increased anaphase-promoting complex binding

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FYPO:0007385 - increased duration of protein-protein interaction

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FYPO:0007835 - increased histone binding

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FYPO:0008196 - increased histone H3-K9Me binding

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FYPO:0001571 - increased protein-protein interaction

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FYPO:0007621 - increased protein-protein interaction during cellular response to oxidative stress

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