Phenotype ontology term - FYPO:0001329 - decreased level of substance in cell during vegetative growth

FYPO:0002835 - centromeric outer repeat transcript-derived siRNA absent

References:

• PMID:24240238

Genes:

• dcr1 (SPCC188.13c)
• poz1 (SPAC19G12.13c)
• rap1 (SPBC1778.02)
• taz1 (SPAC16A10.07c)

Genotypes:

• dcr1delta poz1delta
• dcr1delta rap1delta
• dcr1delta taz1delta

FYPO:0001712 - coenzyme Q10 absent from cell

References:

• PMID:24911838
• PMID:27837315

Genes:

• dlp1 (SPAC19G12.12)
• dps1 (SPBPJ4664.01)

Genotypes:

• dlp1delta dps1delta

FYPO:0004816 - decreased antisense RNA level

References:

• PMID:38181050

Genes:

• clr4 (SPBC428.08c)
• lsd2 (SPAC23E2.02)

Genotypes:

• clr4delta lsd2-deltaC(1165-1235 Δaa)

FYPO:0005158 - decreased cell wall (1->6)-beta-D-glucan level

References:

• PMID:21124977

Genes:

• gas2 (SPBC29A10.08)
• gas5 (SPAC11E3.13c)

Genotypes:

• gas2delta gas5delta

FYPO:0001081 - decreased cell wall alpha-glucan level

References:

• PMID:40668835

Genes:

• aah1 (SPCC757.12)
• aah3 (SPCC63.02c)

Genotypes:

• aah1delta aah3delta

FYPO:0002265 - decreased cell wall galactomannan level

References:

• PMID:40668835

Genes:

• aah1 (SPCC757.12)
• aah3 (SPCC63.02c)

Genotypes:

• aah1delta aah3delta

FYPO:0006978 - decreased cellular coenzyme Q10 level

References:

• PMID:42024429

Genes:

• idp1 (SPAC6G10.08)
• pos5 (SPAC323.01c)

Genotypes:

• idp1delta pos5delta

FYPO:0002571 - decreased cellular dGTP level

References:

• PMID:28640807

Genes:

• trx1 (SPAC7D4.07c)
• txl1 (SPBC577.08c)

Genotypes:

• trx1delta txl1delta

FYPO:0006144 - decreased cellular gluconate level

References:

• PMID:28667014

Genes:

• gcd1 (SPCC794.01c)
• loz1 (SPAC25B8.19c)

Genotypes:

• gcd1delta loz1delta

FYPO:0001570 - decreased cellular glutathione level during vegetative growth

References:

• PMID:12787490
• PMID:9017391

Genes:

• ade6 (SPCC1322.13)
• atf1 (SPBC29B5.01)
• gcs1 (SPAC22F3.10c)
• gsa1 (SPAC3F10.04)
• sty1 (SPAC24B11.06c)

Genotypes:

• ade6-M210(P489L aa) gcs1delta
• ade6-M210(P489L aa) gsa1delta
• atf1delta sty1delta

FYPO:0005630 - decreased cellular HMW SUMO conjugate level

References:

• PMID:21444718
• PMID:26221037
• PMID:41330900

Genes:

• nup132 (SPAC1805.04)
• pli1 (SPAC1687.05)
• pmt3 (SPBC365.06)
• slx8 (SPBC3D6.11c)

Genotypes:

• nup132delta pmt3+(wild type)[Overexpression]
• nup132delta slx8-29(unknown)
• pli1delta pmt3-D81R(aa)
• pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa) slx8-29(unknown)

FYPO:0005001 - decreased cellular HMW ubiquitin conjugate level

References:

• PMID:10082519

Genes:

• cut20 (SPAC19G12.01c)
• dim1 (SPCC16A11.05c)
• rpn12 (SPBC16G5.01)

Genotypes:

• dim1-35(G126D aa) mts3-1(unknown)
• lid1-6(unknown) mts3-1(unknown)

FYPO:0005774 - decreased cellular magnesium level

References:

• PMID:27560651

Genes:

• mnr2 (SPAC17A2.14)
• SPBC27B12.12c

Genotypes:

• SPBC27B12.12cdelta mnr2delta

FYPO:0001285 - decreased cellular phosphatidylethanolamine level

References:

• PMID:19286980

Genes:

• psd1 (SPBC16E9.18)
• psd2 (SPAC25B8.03)
• psd3 (SPAC31G5.15)

Genotypes:

• psd1delta psd2delta psd3delta

FYPO:0006881 - decreased cellular phytoceramide level

References:

• PMID:30975915

Genes:

• bqt4 (SPBC19C7.10)
• elo2 (SPAC1B2.03c)
• lem2 (SPAC18G6.10)

Genotypes:

• bqt4delta elo2+(wild type)[Overexpression] lem2+(wild type)[Knockdown]
• bqt4delta lem2+(wild type)[Knockdown]

FYPO:0002829 - decreased cellular phytochelatin level

References:

• PMID:1448066
• PMID:20937798

Genes:

• abc1 (SPAC9E9.12c)
• abc2 (SPAC3F10.11c)
• abc3 (SPBC359.05)
• abc4 (SPAC30.04c)
• ade2 (SPAC144.03)
• ade6 (SPCC1322.13)
• ade7 (SPBC409.10)
• hmt1 (SPCC737.09c)

Genotypes:

• abc1delta abc2delta abc3delta abc4delta hmt1delta
• ade2::URA3(disruption) ade6-216(unknown)
• ade2::URA3(disruption) ade7.50(unknown)

FYPO:0008024 - decreased cellular polyphosphate level

References:

• PMID:35012333

Genes:

• asp1 (SPCC1672.06c)
• pqr1 (SPAC6B12.07c)

Genotypes:

• asp1-D333A(aa) pqr1delta
• asp1delta pqr1delta

FYPO:0005585 - decreased cellular triglyceride level during vegetative growth

References:

• PMID:18653539
• PMID:26990381

Genes:

• dga1 (SPCC1235.15)
• plh1 (SPBC776.14)

Genotypes:

• dga1delta plh1delta

FYPO:0003094 - decreased centromeric outer repeat transcript level

References:

• PMID:19111658
• PMID:22268381

Genes:

• chp1 (SPAC18G6.02c)
• chp2 (SPBC16C6.10)
• rdp1 (SPAC6F12.09)
• sal3 (SPCC1840.03)
• swi6 (SPAC664.01c)

Genotypes:

• chp1delta chp2delta
• chp1delta chp2delta swi6delta
• chp1delta swi6delta
• chp2delta swi6delta
• rdp1-SV40-NLS sal3delta

FYPO:0004201 - decreased centromeric outer repeat transcript-derived siRNA level

References:

• PMID:20178743
• PMID:21436456
• PMID:28541282
• PMID:41316862
• PMID:42420319

Genes:

• ago1 (SPCC736.11)
• cid12 (SPCC663.12)
• cid14 (SPAC12G12.13c)
• eas1 (SPAC18G6.13)
• elp1 (SPBC36.07)
• hht1 (SPAC1834.04)
• mlo3 (SPBC1D7.04)
• mug174 (SPCC1682.03c)
• pac1 (SPBC119.11c)
• pir2 (SPBC725.08)
• rdp1 (SPAC6F12.09)
• rpb2 (SPAC23G3.01)
• swi6 (SPAC664.01c)
• tgs1 (SPAC2G11.15c)

Genotypes:

• ago1+(wild type) ago1-D580A(aa)
• cid12delta cid14delta
• cid12delta rdp1+(wild type)[Overexpression]
• eas1delta swi6delta
• elp1delta rpb2-m203(N44Y aa)
• hht1-K9R(K10R aa) mlo3-KA(K165A,K167A aa)
• mug174delta swi6delta
• pac1-A342T(aa) swi6delta
• pir2-1(F165L,S316P aa) swi6delta
• swi6delta tgs1-G154D(aa)
• swi6delta tgs1delta

FYPO:0003447 - decreased level of glycosylated protein in cell

References:

• PMID:9839953

Genes:

• gma12 (SPCC736.04c)
• gmh3 (SPAC22E12.06c)

Genotypes:

• gma12::ura4+ gmh3::LEU2+

FYPO:0004906 - decreased level of histone gene mRNA during vegetative growth

References:

• PMID:27901072

Genes:

• ams2 (SPCC290.04)

Genotypes:

• ams2+(wild type) ams2-C1(1-143 Δaa)
• ams2+(wild type) ams2-MZF(C375A,C378A aa)[Overexpression]

FYPO:0004880 - decreased level of lipid metabolism gene mRNA during vegetative growth

References:

• PMID:38780300
• PMID:39652606

Genes:

• cbf11 (SPCC736.08)
• mga2 (SPAC26H5.05)

Genotypes:

• cbf11delta mga2delta

FYPO:0002775 - decreased level of sumoylated protein in cell

References:

• PMID:12597774
• PMID:26221037

Genes:

• hus5 (SPAC30D11.13)
• nup132 (SPAC1805.04)
• ulp2 (SPAC17A5.07c)

Genotypes:

• hus5+(wild type) hus5.62(A129V aa)[Overexpression]
• nup132delta ulp2delta

FYPO:0005187 - decreased level of transport gene mRNA during vegetative growth

References:

• PMID:38780300

Genes:

• cbf11 (SPCC736.08)
• mga2 (SPAC26H5.05)

Genotypes:

• cbf11delta mga2delta

FYPO:0005226 - decreased level of ubiquitinated protein in cell

References:

• PMID:41330900

Genes:

• pmt3 (SPBC365.06)
• rad8 (SPAC13G6.01c)

Genotypes:

• pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa) rad8delta

FYPO:0001137 - decreased mature 25S rRNA level

References:

• PMID:28541282

Genes:

• cid14 (SPAC12G12.13c)
• rdp1 (SPAC6F12.09)

Genotypes:

• cid14delta rdp1+(wild type)[Overexpression]

FYPO:0006470 - decreased mature rRNA level

References:

• PMID:41258116

Genes:

• tor1 (SPBC30D10.10c)
• tor2 (SPBC216.07c)

Genotypes:

• tor1delta tor2-L2048S(aa)

FYPO:0002932 - decreased mature snoRNA level

References:

• PMID:20129053

Genes:

• pab2 (SPBC16E9.12c)
• rrp6 (SPAC1F3.01)

Genotypes:

• pab2delta rrp6delta

FYPO:0002583 - decreased mature tRNA level during vegetative growth

References:

• PMID:28977649
• PMID:32841241
• PMID:35901126

Genes:

• dhp1 (SPAC26A3.12c)
• gcn1 (SPAC18G6.05c)
• gcn3 (SPCC11E10.07c)
• sla1 (SPAC57A10.10c)
• tol1 (SPCC1753.04)
• trm1 (SPBC25D12.05)
• trm6 (SPBC800.08)
• trm8 (SPCPB16A4.04c)

Genotypes:

• dhp1-2(R218Q aa) trm8delta
• dhp1-6(Y669C aa) trm6delta
• dhp1-W326L(aa) trm8delta
• gcn1-1(2193-2195 Δaa) trm8delta
• sla1delta trm1delta
• tif221-1(Q257*) trm8delta
• tif221-2(fs@L43) trm8delta
• tol1-1(A151D aa) trm6delta

FYPO:0003915 - decreased mitochondrial protein level

References:

• PMID:28334955
• PMID:34634819

Genes:

• cbp7 (SPBC28E12.04)
• cbp8 (SPAC22H10.09)
• lon1 (SPAC22F3.06c)
• mpa1 (SPAPB1E7.11c)
• mug178 (SPBC2G2.07c)

Genotypes:

• cbp7delta mug178delta
• cbp8delta mug178delta
• lon1delta mpa1delta

FYPO:0003423 - decreased mitochondrial RNA level

References:

• PMID:18304578

Genes:

• pet127 (SPCC1183.04c)
• rpm1 (SPCC1322.01)
• rpm2 (SPAC637.11)

Genotypes:

• pet127+(wild type)[Overexpression] rpm1delta
• pet127+(wild type)[Overexpression] rpm1delta rpm2delta
• pet127+(wild type)[Overexpression] rpm2delta

FYPO:0003103 - decreased mRNA-derived small RNA level

References:

• PMID:24210919

Genes:

• cwf10 (SPBC215.12)
• nrl1 (SPBC20F10.05)
• rrp6 (SPAC1F3.01)

Genotypes:

• cwf10-1(C324Y aa) rrp6delta
• nrl1delta rrp6delta

FYPO:0006623 - decreased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane

References:

• PMID:29975157

Genes:

• efr3 (SPCC794.08)
• its3 (SPAC19G12.14)
• pik3 (SPAC458.05)
• ptn1 (SPBC609.02)

Genotypes:

• efr3delta ptn1delta
• its3-1(G281D aa) ptn1delta
• pik3delta ptn1delta

FYPO:0006628 - decreased phosphatidylinositol-4-phosphate level in plasma membrane

References:

• PMID:29975157
• PMID:39110593

Genes:

• csr102 (SPAC3H8.02)
• efr3 (SPCC794.08)
• lsb6 (SPAC343.19)
• pdr16 (SPCC23B6.04c)
• spo20 (SPAC3H8.10)

Genotypes:

• csr102delta pdr16delta
• csr102delta pdr16delta spo20delta
• csr102delta spo20delta
• efr3delta lsb6delta
• pdr16delta spo20delta

FYPO:0008133 - decreased phosphatidylinositol-4-phosphate level in the Golgi

References:

• PMID:39540318

Genes:

• gga21 (SPAC1F3.05)
• gga22 (SPBC25H2.16c)

Genotypes:

• gga21delta gga22delta

FYPO:0008342 - decreased pre-tRNA or mature level during vegetative growth

References:

• PMID:38295128

Genes:

• rpl1102 (SPBC17G9.10)
• rpl1502 (SPAC1783.08c)
• rpl1701 (SPBC2F12.04)
• rpl502 (SPBC11C11.09c)
• tan1 (SPBC25H2.10c)
• trm8 (SPCPB16A4.04c)

Genotypes:

• rpl1102-K93X(K93*) trm8delta
• rpl1502delta trm8delta
• rpl1701-Q72X trm8delta
• rpl502-Y44X trm8delta
• rpl502delta tan1delta

FYPO:0006885 - decreased protein level at mitotic spindle

References:

• PMID:30463883

Genes:

• alp16 (SPCC4G3.19)
• cut7 (SPAC25G10.07c)
• mal3 (SPAC18G6.15)

Genotypes:

• alp16delta cut7-22(P1021S aa)
• cut7-22(P1021S aa) mal3delta

FYPO:0003151 - decreased protein level during cellular response to heat

References:

• PMID:38181050

Genes:

• hht1 (SPAC1834.04)
• hht2 (SPBC8D2.04)
• hht3 (SPBC1105.11c)

Genotypes:

• hht1-K4R(K5R aa) hht2-K4R(K5R aa) hht3-K4R(K5R aa)

FYPO:0001274 - decreased protein level during cellular response to hypoxia

References:

• PMID:28202541

Genes:

• mga2 (SPAC26H5.05)
• sre1 (SPBC19C2.09)

Genotypes:

• mga2delta sre1-MP(CACCCCAT(-528)ATACCATA,CAGTCCAC(-485)ATATCATA)[Knockdown]

FYPO:0003651 - decreased protein level during cellular response to nitrosative stress

References:

• PMID:12787490

Genes:

• atf1 (SPBC29B5.01)
• sty1 (SPAC24B11.06c)

Genotypes:

• atf1delta sty1delta

FYPO:0007523 - decreased protein level during cellular response to oxidative stress

References:

• PMID:19625445

Genes:

• cpc2 (SPAC6B12.15)
• tif211 (SPAC3G9.09c)

Genotypes:

• cpc2delta tif211-S52A(aa)

FYPO:0003930 - decreased protein level during cellular response to salt stress

References:

• PMID:19625445

Genes:

• cpc2 (SPAC6B12.15)
• tif211 (SPAC3G9.09c)

Genotypes:

• cpc2delta tif211-S52A(aa)

FYPO:0005933 - decreased protein level during mitotic G1 phase

References:

• PMID:9303310
• PMID:9312055

Genes:

• cdc10 (SPBC336.12c)
• cdc13 (SPBC582.03)
• cut2 (SPBC14C8.01c)

Genotypes:

• cdc10-(unknown) cut2-ddm(R28A,L31A,R47A,L50A aa)[Overexpression]
• cdc10-129(T429A aa) cdc13+(wild type)[Knockdown]

FYPO:0001324 - decreased protein level during vegetative growth

References:

• PMID:11084332
• PMID:12787490
• PMID:16317047
• PMID:18062930
• PMID:22173095
• PMID:22768388
• PMID:25356590
• PMID:25639242
• PMID:26221037
• PMID:26369364
• PMID:27398807
• PMID:27655872
• PMID:31927482
• PMID:32053662
• PMID:34086083
• PMID:35082773
• PMID:35171902
• PMID:35320724
• PMID:41201383
• PMID:7813446

Genes:

• ace2 (SPAC6G10.12c)
• acp1 (SPAC12B10.07)
• amk2 (SPCC1919.03c)
• atf1 (SPBC29B5.01)
• cay1 (SPBC2F12.12c)
• cbs2 (SPAC1556.08c)
• cdc48 (SPAC1565.08)
• cut4 (SPBC106.09)
• elp3 (SPAC29A4.20)
• epe1 (SPCC622.16c)
• git3 (SPCC1753.02c)
• gsk3 (SPAC1687.15)
• gsk31 (SPBC8D2.01)
• hht1 (SPAC1834.04)
• hht2 (SPBC8D2.04)
• hht3 (SPBC1105.11c)
• hsp90 (SPAC926.04c)
• int6 (SPBC646.09c)
• ksg1 (SPCC576.15c)
• mug14 (SPBC359.06)
• nup132 (SPAC1805.04)
• pab1 (SPAC227.07c)
• pdk1 (SPBC1778.10c)
• pka1 (SPBC106.10)
• poz1 (SPAC19G12.13c)
• pts1 (SPAC4A8.13c)
• rap1 (SPBC1778.02)
• rbd2 (SPCC790.03)
• rpn12 (SPBC16G5.01)
• rpt2 (SPBC4.07c)
• rst2 (SPAC6F12.02)
• sdj1 (SPAC22E12.03c)
• sep1 (SPBC4C3.12)
• smn1 (SPAC2G11.08c)
• ssp2 (SPCC74.03c)
• sty1 (SPAC24B11.06c)
• tls1 (SPAC1D4.01)
• tor2 (SPBC216.07c)
• tsn1 (SPAC30.03c)
• ufd1 (SPBC16A3.09c)
• wee1 (SPCC18B5.03)
• SPATRNALYS.02

Genotypes:

• SPATRNALYS.02+(wild type)[Overexpression] elp3delta
• ace2delta sep1+(wild type)[Overexpression]
• acp1delta tdSMN(Ub-DHFRts-smn1)
• amk2delta cbs2delta
• atf1delta sty1delta
• cay1delta poz1-intronless(107-143,491-584 Δnt) tls1delta
• cay1delta rap1-intronless(97-142,515-597 Δnt) tls1delta
• cdc48-353(G332D aa) int6+(wild type)[Overexpression]
• cdc48-353(G332D aa) tor2-S1837E(aa)
• cdc48-353(G332D aa) ufd1-5(L281S aa)
• cut4-ts(unknown) mts2-1(unknown)
• epe1+(wild type)[Overexpression] git3delta
• epe1+(wild type)[Overexpression] pka1delta
• gsk31delta gsk3delta
• gsk31delta gsk3delta ssp2delta
• hht1-K4A(K5A aa) hht2-K4A(K5A aa) hht3-K4A(K5A aa)
• hht1delta hht2-S86A,S87A(S87A,S88A aa) hht3delta
• hsp90-G84C(aa) wee1-50(G850E aa)[Overexpression]
• ksg1-208(G159E aa) pdk1delta
• mts3-1(unknown) nup132delta
• mts3-1(unknown) rbd2delta
• mts3-1(unknown) tsn1delta
• mug14-STREP-KO1((-209)-(-204)) pka1delta
• mug14-STREP-KO2((-192)-(-187)) pka1delta
• mug14-STREP-KO3((-209)-(-204),(-192)-(-187)) pka1delta
• nup132delta pab1-1(I228ITEVI)
• nup132delta ufd1-1(P76S aa)
• pka1delta rst2-C2H2delta(70-97 Δaa)[Overexpression]
• pts1-732(unknown) sdj1-L166P(aa)
• pts1-732(unknown) sdj1-L169P(aa)

FYPO:0002287 - decreased RNA level during cellular response to heat

References:

• PMID:15358115

Genes:

• atf1 (SPBC29B5.01)
• pap1 (SPAC1783.07c)

Genotypes:

• atf1delta pap1delta

FYPO:0001116 - decreased RNA level during cellular response to hydrogen peroxide

References:

• PMID:10749922
• PMID:15358115
• PMID:28652406

Genes:

• atf1 (SPBC29B5.01)
• pap1 (SPAC1783.07c)
• pcr1 (SPAC21E11.03c)
• wis1 (SPBC409.07c)

Genotypes:

• atf1-7D(S140D,S152D,S172D,T204E,T216E,S226D,T249E aa) pcr1delta
• atf1delta pap1delta
• pap1delta wis1-DD(S469D,T473D aa)

FYPO:0002975 - decreased RNA level during cellular response to hydroxyurea

References:

• PMID:19750219
• PMID:26912660
• PMID:28903048

Genes:

• cdc10 (SPBC336.12c)
• chk1 (SPCC1259.13)
• rad3 (SPBC216.05)
• set2 (SPAC29B12.02c)
• tor1 (SPBC30D10.10c)
• yox1 (SPBC21B10.13c)

Genotypes:

• cdc10-2E(S720E,T723E aa) rad3delta
• cdc10-2E(S720E,T723E aa) tor1delta
• chk1delta set2delta
• tor1delta yox1delta

FYPO:0003142 - decreased RNA level during cellular response to methyl methanesulfonate

References:

• PMID:11073995
• PMID:19750219

Genes:

• cdc10 (SPBC336.12c)
• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)
• rad3 (SPBC216.05)

Genotypes:

• cdc10-2E(S720E,T723E aa) rad3delta
• cds1delta chk1delta

FYPO:0001280 - decreased RNA level during cellular response to oxidative stress

References:

• PMID:28652406

Genes:

• atf1 (SPBC29B5.01)
• pap1 (SPAC1783.07c)
• sty1 (SPAC24B11.06c)

Genotypes:

• atf1-10D/E(S2D,S4D,T77E,S140D,S152D,S172D,T204E,T216E,S226D,T249E aa)[Overexpression] pap1delta sty1delta

FYPO:0004416 - decreased RNA level during cellular response to phosphate starvation

References:

• PMID:23231582

Genes:

• csk1 (SPAC1D4.06c)
• pho7 (SPBC27B12.11c)

Genotypes:

• csk1delta pho7delta

FYPO:0002304 - decreased RNA level during cellular response to salt stress

References:

• PMID:12221110

Genes:

• atf1 (SPBC29B5.01)
• pcr1 (SPAC21E11.03c)
• tup11 (SPAC18B11.10)
• tup12 (SPAC630.14c)

Genotypes:

• atf1delta tup11delta tup12delta
• pcr1delta tup11delta tup12delta

FYPO:0007084 - decreased RNA level during cellular response to sulfur starvation

References:

• PMID:28388826

Genes:

• ecl1 (SPCC70.12c)
• ecl2 (SPBP35G2.16c)
• ecl3 (SPBC8E4.12c)

Genotypes:

• ecl1delta ecl2delta ecl3delta

FYPO:0003034 - decreased RNA level during cellular response to UV

References:

• PMID:11073995

Genes:

• cds1 (SPCC18B5.11c)
• chk1 (SPCC1259.13)

Genotypes:

• cds1delta chk1delta

FYPO:0006334 - decreased RNA level during cellular response to zinc ion starvation

References:

• PMID:25204792

Genes:

• ecl1 (SPCC70.12c)
• ecl2 (SPBP35G2.16c)
• ecl3 (SPBC8E4.12c)

Genotypes:

• ecl1delta ecl2delta ecl3delta

FYPO:0001117 - decreased RNA level during vegetative growth

References:

• PMID:11739717
• PMID:17179073
• PMID:17371846
• PMID:22212525
• PMID:23115244
• PMID:23122962
• PMID:25533348
• PMID:26369364
• PMID:26689777
• PMID:33533152
• PMID:34086083
• PMID:39094565
• PMID:40402811
• PMID:9303312

Genes:

• ago1 (SPCC736.11)
• cdc10 (SPBC336.12c)
• cdk9 (SPBC32H8.10)
• dcr1 (SPCC188.13c)
• ecl1 (SPCC70.12c)
• ecl2 (SPBP35G2.16c)
• ecl3 (SPBC8E4.12c)
• ell1 (SPBP23A10.14c)
• epe1 (SPCC622.16c)
• fep1 (SPAC23E2.01)
• fxn1 (SPCC1183.03c)
• gcn5 (SPAC1952.05)
• grx4 (SPBC26H8.06)
• gtr1 (SPBC337.13c)
• gtr2 (SPCC777.05)
• hht1 (SPAC1834.04)
• hht2 (SPBC8D2.04)
• hht3 (SPBC1105.11c)
• htb1 (SPCC622.09)
• lam2 (SPBC1778.05c)
• lsd1 (SPBC146.09c)
• lsd2 (SPAC23E2.02)
• mst2 (SPAC17G8.13c)
• mug14 (SPBC359.06)
• npr2 (SPAC23H3.03c)
• npr3 (SPBC543.04)
• nrm1 (SPBC16A3.07c)
• pka1 (SPBC106.10)
• pmc3 (SPAC17C9.05c)
• pmc4 (SPBC1105.06)
• prr1 (SPAC8C9.14)
• red1 (SPAC1006.03c)
• res1 (SPBC725.16)
• res2 (SPAC22F3.09c)
• rst2 (SPAC6F12.02)
• sty1 (SPAC24B11.06c)
• tor1 (SPBC30D10.10c)
• tor2 (SPBC216.07c)
• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)
• ubp8 (SPAC13A11.04c)

Genotypes:

• ago1delta epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta
• cdc10delta sct1-1(unknown)
• cdk9+(wild type) cdk9+(wild type) epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta
• dcr1delta epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta
• ecl1+(wild type)[Overexpression] prr1delta
• ecl2+(wild type)[Overexpression] prr1delta
• ecl3+(wild type)[Overexpression] prr1delta
• ell1delta epe1(1-402)(403-948 Δaa)[Overexpression]
• epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) gcn5delta mst2delta
• epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron)
• epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta
• epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta red1delta
• epe1-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron) mst2delta sty1delta
• epe1delta mst2-3XFLAG-AID(C-term tag with 3XFLAG bridging to auxin-inducible degron)
• epe1delta mst2delta
• fep1delta fxn1delta
• fxn1delta grx4delta
• gtr1delta tor2-L2048S(aa)
• gtr2delta tor2-L2048S(aa)
• hht1delta hht2-S86A,S87A(S87A,S88A aa) hht3delta
• htb1-D67N(D68N aa) ubp8delta
• htb1-P102L(P103L aa) ubp8delta
• lam2delta tor2-L2048S(aa)
• lsd1-ao(K603A,K604A aa) lsd2-ao(K823A,K824A aa)
• med27-S235A(aa) med4-S115A,S204A,S218A(aa)
• mug14-STREP-KO1((-209)-(-204)) pka1delta
• mug14-STREP-KO2((-192)-(-187)) pka1delta
• mug14-STREP-KO3((-209)-(-204),(-192)-(-187)) pka1delta
• npr2::kanMX4[Null] tor2-L2048S(aa)
• npr2::ura4+[Null] tor2-L2048S(aa)
• npr3delta tor2-L2048S(aa)
• nrm1delta res2delta
• pka1delta rst2delta
• tor1delta tsc1delta
• tor1delta tsc2delta

FYPO:0008424 - decreased silent mating-type cassette transcript-derived siRNA level

References:

• PMID:39747188

Genes:

• cwf10 (SPBC215.12)
• moc3 (SPAC821.07c)
• php3 (SPAC23C11.08)
• swi6 (SPAC664.01c)

Genotypes:

• cwf10-1(C324Y aa) swi6delta
• moc3delta swi6delta
• php3delta swi6delta

FYPO:0008269 - decreased total cellular phosphate (Pi) level

References:

• PMID:37949217

Genes:

• pqr1 (SPAC6B12.07c)
• vtc4 (SPCC1322.14c)

Genotypes:

• pqr1delta vtc4delta

FYPO:0003236 - decreased transposable element-derived small RNA level

References:

• PMID:24210919
• PMID:25002536

Genes:

• cwf10 (SPBC215.12)
• mug165 (SPAC5D6.02c)
• nrl1 (SPBC20F10.05)
• nts1 (SPCC24B10.19c)
• png3 (SPAC16E8.12c)
• rrp6 (SPAC1F3.01)

Genotypes:

• cwf10-1(C324Y aa) rrp6delta
• mug165delta nts1delta png3delta
• nrl1delta rrp6delta

FYPO:0000453 - DNA content decreased during vegetative growth

References:

• PMID:25533348
• PMID:7700230
• PMID:8121488
• PMID:9154809

Genes:

• cdc10 (SPBC336.12c)
• cdc18 (SPBC14C8.07c)
• cdc20 (SPBC25H2.13c)
• cdc6 (SPBC336.04)
• chk1 (SPCC1259.13)
• cig2 (SPAPB2B4.03)
• mcm4 (SPCC16A11.17)
• nrm1 (SPBC16A3.07c)
• rad26 (SPAC9E9.08)
• rum1 (SPBC32F12.09)

Genotypes:

• cdc10-129(T429A aa) rum1delta
• cdc18-K46(unknown) chk1delta
• cdc20-M10(unknown) chk1delta
• cdc21-M68(unknown) rad26.a14(C510CNPLIVC)
• cdc6-ts3(R1064Q aa) chk1delta
• cig2+(wild type)[Overexpression] nrm1delta

FYPO:0001723 - ferrichrome absent from cell

References:

• PMID:20435771

Genes:

• sib1 (SPAC23G3.02c)
• sib2 (SPAC23G3.03)

Genotypes:

• sib1delta sib2delta

FYPO:0003133 - galactomannan absent from cell wall

References:

• PMID:40668835

Genes:

• aah1 (SPCC757.12)
• aah3 (SPCC63.02c)

Genotypes:

• aah1delta aah3delta

FYPO:0003727 - galactose absent from cell wall glycoprotein glycan

References:

• PMID:23254763

Genes:

• ght2 (SPBC4B4.08)
• uge1 (SPBC365.14c)

Genotypes:

• ght2delta uge1delta

FYPO:0001211 - Glc3Man9GlcNAc absent from cell

References:

• PMID:30389790

Genes:

• alg10 (SPAC56F8.06c)
• gls1 (SPAC6G10.09)

Genotypes:

• alg10-N184*(aa) gls1delta
• alg10delta gls1delta

FYPO:0008262 - mannosylinositol phosphorylceramide absent from cell

References:

• PMID:20388730

Genes:

• imt1 (SPAC2F3.01)
• imt2 (SPCC4F11.04c)
• imt3 (SPAC17G8.11c)

Genotypes:

• imt1delta imt2delta imt3delta

FYPO:0004912 - phytochelatin absent from vacuole

References:

• PMID:20937798

Genes:

• abc1 (SPAC9E9.12c)
• abc2 (SPAC3F10.11c)
• abc3 (SPBC359.05)
• abc4 (SPAC30.04c)
• hmt1 (SPCC737.09c)

Genotypes:

• abc1delta abc2delta abc3delta abc4delta hmt1delta

FYPO:0007820 - polyphosphate absent from cell

References:

• PMID:35012333

Genes:

• asp1 (SPCC1672.06c)
• vtc4 (SPCC1322.14c)

Genotypes:

• asp1(1-385)(386-920 Δaa) vtc4delta

FYPO:0001984 - protein absent from cell during vegetative growth

References:

• PMID:12535531

Genes:

• cnp1 (SPBC1105.17)
• mis6 (SPAC1687.20c)

Genotypes:

• cnp1-1(L87Q aa) mis6+(wild type)[Overexpression]

FYPO:0008156 - RNA absent from cell during cellular response to glucose starvation

References:

• PMID:18820678

Genes:

• atf1 (SPBC29B5.01)
• tup11 (SPAC18B11.10)
• tup12 (SPAC630.14c)

Genotypes:

• atf1-(unknown) tup11delta tup12delta

FYPO:0004052 - RNA absent from cell during cellular response to hydrogen peroxide

References:

• PMID:28652406

Genes:

• atf1 (SPBC29B5.01)
• sty1 (SPAC24B11.06c)

Genotypes:

• atf1-10M(S2A,S4A,T77I,S140A,S152A,S172A,T204I,T216I,S226A,T249I aa)[Overexpression] sty1delta

FYPO:0003162 - RNA absent from cell during cellular response to salt stress

References:

• PMID:10749922

Genes:

• atf1 (SPBC29B5.01)
• pap1 (SPAC1783.07c)

Genotypes:

• atf1delta pap1delta

FYPO:0003161 - RNA absent from cell during vegetative growth

References:

• PMID:29414789
• PMID:9671458

Genes:

• nrd1 (SPAC2F7.11)
• pho7 (SPBC27B12.11c)
• prt2 (SPNCRNA.9001)
• wis1 (SPBC409.07c)

Genotypes:

• nrd1delta wis1delta
• pho7delta prt2delta-1(231 nt promoter and transcription start site deletion)[Null]
• pho7delta prt2delta-2(749 nt promoter and transcription start site deletion)[Null]

FYPO:0006076 - siRNA absent from cell

References:

• PMID:17531816
• PMID:32415063

Genes:

• ago1 (SPCC736.11)
• cwf10 (SPBC215.12)
• nc-pho1 (SPNCRNA.1712)
• pir2 (SPBC725.08)
• rrp6 (SPAC1F3.01)
• tas3 (SPBC83.03c)

Genotypes:

• ago1-F276A(aa) tas3-W265A,G266A(aa)
• cwf10-1(C324Y aa) rrp6delta
• nc-pho1-5'cryptic-splice1(1723-1726 Δnt) rrp6delta
• pir2-1(F165L,S316P aa) rrp6delta

FYPO:0006974 - triglyceride absent from cell

References:

• PMID:28282432

Genes:

• dga1 (SPCC1235.15)
• plh1 (SPBC776.14)

Genotypes:

• dga1delta plh1delta

FYPO:0005678 - ubiquitinated protein absent from cell during vegetative growth

References:

• PMID:27151298

Genes:

• rad8 (SPAC13G6.01c)
• rhp18 (SPBC1734.06)
• ubp15 (SPBC713.02c)
• ubp16 (SPCC1682.12c)
• ubp2 (SPAC328.06)

Genotypes:

• rad8delta ubp2-NES
• rad8delta ubp2delta
• rhp18delta ubp15-NES ubp16delta ubp2delta
• rhp18delta ubp2-NES
• rhp18delta ubp2delta

FYPO:0007065 - 20S rRNA precursor absent from cell

References:

• PMID:29641590

Genes:

• utp24 (SPBC32H8.04c)

Genotypes:

• utp24+(wild type)[Knockdown]

FYPO:0003159 - cAMP absent from cell

References:

• PMID:1863602

Genes:

• cyr1 (SPBC19C7.03)

Genotypes:

• cyr1delta

FYPO:0002835 - centromeric outer repeat transcript-derived siRNA absent

References:

• PMID:16931764
• PMID:17310250
• PMID:18345014
• PMID:19362535
• PMID:20178743
• PMID:20211136
• PMID:20299449
• PMID:21725325
• PMID:22474355
• PMID:22727667
• PMID:22895252
• PMID:23613586
• PMID:24240238
• PMID:27738016
• PMID:28231281
• PMID:29866182
• PMID:33693625

Genes:

• ago1 (SPCC736.11)
• arb1 (SPAC140.03)
• cdc20 (SPBC25H2.13c)
• chp1 (SPAC18G6.02c)
• clr4 (SPBC428.08c)
• dcr1 (SPCC188.13c)
• dri1 (SPAC17H9.04c)
• dsh1 (SPBC582.04c)
• ers1 (SPCC1393.05)
• hsp90 (SPAC926.04c)
• mas5 (SPBC1734.11)
• prp16 (SPBC1711.17)
• rdp1 (SPAC6F12.09)
• stc1 (SPBP8B7.28c)
• tas3 (SPBC83.03c)

Genotypes:

• ago1-D580A(aa)
• ago1delta
• arb1delta
• cdc20-P7(unknown)
• chp1-E23V(aa)
• chp1-V24M(aa)
• chp1-V24R(aa)
• chp1-W44A(aa)
• chp1delta
• chp1deltaCD(2-79)(aa)
• clr4delta
• dcr1delta
• dri1delta
• dsh1delta
• ers1-C62(S234P aa)
• hsp90-A4(R33C aa)
• mas5delta
• prp16-2(Q140*)
• rdp1delta
• stc1-deltaZF1+2(32-126 Δaa)
• stc1-deltaZF2(89-126 Δaa)
• stc1delta
• tas3delta

FYPO:0000273 - centromeric outer repeat transcripts absent

References:

• PMID:15947136
• PMID:19111658
• PMID:21847092

Genes:

• dcr1 (SPCC188.13c)
• rpb2 (SPAC23G3.01)
• swi6 (SPAC664.01c)

Genotypes:

• dcr1-SHSS(C1275S,C1350S,C1352S aa)
• dcr1delta
• rpb2-m203(N44Y aa)
• swi6delta

FYPO:0001712 - coenzyme Q10 absent from cell

References:

• PMID:11092853
• PMID:14519123
• PMID:14695938
• PMID:16262699
• PMID:18808426
• PMID:19120452
• PMID:24911838
• PMID:9133618

Genes:

• coq3 (SPCC162.05)
• coq4 (SPAC1687.12c)
• coq5 (SPCC4G3.04c)
• coq6 (SPBC146.12)
• coq7 (SPBC337.15c)
• coq8 (SPBC2D10.18)
• dlp1 (SPAC19G12.12)
• dps1 (SPBPJ4664.01)
• ppt1 (SPAC56F8.04c)

Genotypes:

• coq3delta
• coq4delta
• coq5delta
• coq6delta
• coq7delta
• coq8delta
• dlp1delta
• dps1delta
• ppt1delta

FYPO:0003398 - decreased 32S rRNA precursor level

References:

• PMID:24021628

Genes:

• hmo1 (SPBC28F2.11)

Genotypes:

• hmo1delta

FYPO:0003397 - decreased 35S rRNA precursor level

References:

• PMID:24021628

Genes:

• hmo1 (SPBC28F2.11)

Genotypes:

• hmo1delta

FYPO:0008211 - decreased antisense RNA level during heat stress

References:

• PMID:38181050

Genes:

• lsd1 (SPBC146.09c)
• lsd2 (SPAC23E2.02)
• set1 (SPCC306.04c)

Genotypes:

• lsd1-deltaHMG(841-1000 Δaa)
• lsd2-deltaC(1165-1235 Δaa)
• set1delta

FYPO:0007493 - decreased ascospore wall alpha-glucan level

References:

• PMID:16420355

Genes:

• mok12 (SPBC32H8.13c)
• mok13 (SPBC16D10.05)

Genotypes:

• mok12delta/mok12delta
• mok13delta/mok13delta

FYPO:0006362 - decreased borderline-derived siRNA level

References:

• PMID:26438724

Genes:

• swi6 (SPAC664.01c)

Genotypes:

• swi6delta

FYPO:0004013 - decreased cell surface pyruvylated galactose level

References:

• PMID:22180499
• PMID:25195688

Genes:

• pet1 (SPAC22F8.04)
• pet2 (SPBC83.11)
• pvg1 (SPAC8F11.10c)
• pvg2 (SPAC27E2.07)
• pvg3 (SPBC1921.06c)
• pvg5 (SPAC22F8.02c)

Genotypes:

• pet1delta
• pet2delta
• pvg1delta
• pvg2delta
• pvg3delta
• pvg5delta

FYPO:0005158 - decreased cell wall (1->6)-beta-D-glucan level

References:

• PMID:21124977

Genes:

• gas1 (SPAC19B12.02c)
• gas2 (SPBC29A10.08)

Genotypes:

• gas1delta
• gas2delta

FYPO:0001081 - decreased cell wall alpha-glucan level

References:

• PMID:10087262
• PMID:10504305
• PMID:11016847
• PMID:1828464
• PMID:18793338
• PMID:22891259
• PMID:9372443
• PMID:9689051

Genes:

• ags1 (SPCC1281.01)
• cwg2 (SPAC2E1P5.04c)
• pck1 (SPAC17G8.14c)
• pck2 (SPBC12D12.04c)
• rga2 (SPAC26A3.09c)
• rho1 (SPAC1F7.04)
• yam8 (SPAC1F5.08c)

Genotypes:

• ags1+(wild type)[Knockdown]
• ags1-1(G2086A nt)
• cwg2-1(A202T aa)
• ehs1-1(P455S aa)
• mok1-664(Y256F,R408H aa)
• pck1::ura4+
• pck2::LEU2(disruption)
• rga2+(wild type)[Overexpression]
• rho1-F40Y(aa)[Overexpression]

FYPO:0001082 - decreased cell wall beta-glucan level

References:

• PMID:10504305
• PMID:15537393
• PMID:1828464
• PMID:18793338
• PMID:2127797
• PMID:23060961
• PMID:23934882
• PMID:23977061
• PMID:24165938
• PMID:27974503
• PMID:9372443

Genes:

• bch1 (SPBC31F10.16)
• bgs4 (SPCC1840.02c)
• cdc42 (SPAC110.03)
• cfr1 (SPAC6G9.12)
• clc1 (SPBC9B6.08)
• cwg2 (SPAC2E1P5.04c)
• pck1 (SPAC17G8.14c)
• pkd2 (SPAC1F7.03)
• rga2 (SPAC26A3.09c)
• rho1 (SPAC1F7.04)

Genotypes:

• bch1delta
• bgs4+(wild type)[Knockdown]
• cdc42-L160S(aa)
• cfr1delta
• clc1+(wild type)[Knockdown]
• clc1delta
• cwg1-1(unknown)
• cwg2-1(A202T aa)
• pck1::ura4+
• pkd2+(wild type)[Knockdown]
• pkd2+(wild type)[Overexpression]
• rga2+(wild type)[Overexpression]
• rho1-596(C17R aa)
• rho1-F40Y(aa)[Overexpression]
• sph1-1(unknown)

FYPO:0002265 - decreased cell wall galactomannan level

References:

• PMID:15470240
• PMID:21115488
• PMID:2127797
• PMID:22891259
• PMID:9372443

Genes:

• ags1 (SPCC1281.01)
• bgs4 (SPCC1840.02c)
• pmr1 (SPBC31E1.02c)
• rho1 (SPAC1F7.04)

Genotypes:

• ags1+(wild type)[Knockdown]
• cps5-138(W400*)
• pbr1-6(W760S aa)
• pmr1delta
• rho1-D121A(aa)[Overexpression]
• rho1-F40Y(aa)[Overexpression]
• sph1-1(unknown)

FYPO:0008281 - decreased cellular 1,5-IP8 level

References:

• PMID:38940614

Genes:

• asp1 (SPCC1672.06c)
• kcs1 (SPCC970.08)

Genotypes:

• asp1-D333A(aa)
• asp1delta
• kcs1-R332T(aa)

FYPO:0008283 - decreased cellular 1-IP7 level

References:

• PMID:38940614

Genes:

• asp1 (SPCC1672.06c)
• kcs1 (SPCC970.08)

Genotypes:

• asp1-D333A(aa)
• asp1delta
• kcs1-R332T(aa)

FYPO:0007366 - decreased cellular 2,3-bisphosphoglyceric acid level

References:

• PMID:32319721

Genes:

• pyk1 (SPAC4H3.10c)

Genotypes:

• pyk1-T343A(aa)

FYPO:0008282 - decreased cellular 5-IP7 level

References:

• PMID:38940614

Genes:

• kcs1 (SPCC970.08)

Genotypes:

• kcs1-R332T(aa)

FYPO:0006698 - decreased cellular 5-phosphoribosyl diphosphate level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0006712 - decreased cellular acetyl-CoA level

References:

• PMID:28600551

Genes:

• epe1 (SPCC622.16c)
• ssp1 (SPCC297.03)
• ssp2 (SPCC74.03c)

Genotypes:

• epe1delta
• ssp1delta
• ssp2delta

FYPO:0006702 - decreased cellular adenine level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0006967 - decreased cellular AICAR level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0002748 - decreased cellular alanine level

References:

• PMID:14718525

Genes:

• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)

Genotypes:

• tsc1delta
• tsc2delta

FYPO:0001621 - decreased cellular arginine level

References:

• PMID:14718525
• PMID:19734666
• PMID:21307582
• PMID:32896087

Genes:

• atg22 (SPAC2G11.13)
• atp12 (SPAC9.12c)
• cbp3 (SPCC4B3.17)
• cbp8 (SPAC22H10.09)
• mss1 (SPAC222.05c)
• ppr8 (SPBC1289.06c)
• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)
• vma1 (SPAC343.05)

Genotypes:

• atg22delta
• atp12delta
• cbp3delta
• cbp8delta
• mss1delta
• ppr8delta
• tsc1delta
• tsc2delta
• vma1delta

FYPO:0002749 - decreased cellular asparagine level

References:

• PMID:14718525
• PMID:18503766

Genes:

• fnx1 (SPBC12C2.13c)
• fnx2 (SPBC3E7.06c)
• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)

Genotypes:

• fnx1delta
• fnx2delta
• tsc1delta
• tsc2delta

FYPO:0001613 - decreased cellular aspartate level

References:

• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)

Genotypes:

• atg22delta

FYPO:0006971 - decreased cellular biotin level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0006970 - decreased cellular bisphosphoglyceric acid level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0001197 - decreased cellular calcium level

References:

• PMID:11016847
• PMID:36200871

Genes:

• pkd2 (SPAC1F7.03)
• yam8 (SPAC1F5.08c)

Genotypes:

• ehs1-1(P455S aa)
• pkd2-B42(F335S,S408P,N521D,M530V,S534G,Q543E,I555T,I571T,N675K,T676Y,D677*)
• yam8delta

FYPO:0001377 - decreased cellular calcium level during cellular response to salt stress

References:

• PMID:16928959

Genes:

• yam8 (SPAC1F5.08c)

Genotypes:

• yam8delta

FYPO:0006700 - decreased cellular CDP level

References:

• PMID:30072439
• PMID:30240645

Genes:

• cwh43 (SPAC589.12)
• sam1 (SPBC14F5.05c)

Genotypes:

• cwh43-G753R(aa)
• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0001561 - decreased cellular citrulline level

References:

• PMID:14718525

Genes:

• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)

Genotypes:

• tsc1delta
• tsc2delta

FYPO:0006978 - decreased cellular coenzyme Q10 level

References:

• PMID:31030285
• PMID:37156397
• PMID:41926382
• PMID:42024429

Genes:

• atp12 (SPAC9.12c)
• byr1 (SPAC1D4.13)
• byr2 (SPBC1D7.05)
• cbp6 (SPBC947.14c)
• cdk11 (SPBC18H10.15)
• cdr1 (SPAC644.06c)
• cek1 (SPCC1450.11c)
• cgs1 (SPAC8C9.03)
• cki2 (SPBP35G2.05c)
• cki3 (SPAC1805.05)
• cmk2 (SPAC23A1.06c)
• cox5 (SPCC338.10c)
• csk1 (SPAC1D4.06c)
• hhp1 (SPBC3H7.15)
• idp1 (SPAC6G10.08)
• ksp1 (SPBC16E9.13)
• lsk1 (SPAC2F3.15)
• mak1 (SPAC1834.08)
• mde3 (SPBC8D2.19)
• mpa1 (SPAPB1E7.11c)
• mph1 (SPBC106.01)
• pan302 (SPBC336.14c)
• pck1 (SPAC17G8.14c)
• pck2 (SPBC12D12.04c)
• pit1 (SPAC3C7.06c)
• pka1 (SPBC106.10)
• pom2 (SPAC16C9.07)
• por1 (SPAC1635.01)
• pos5 (SPAC323.01c)
• ppk1 (SPAC110.01)
• ppk16 (SPAC890.03)
• ppk22 (SPBC1861.09)
• ppk30 (SPBC6B1.02)
• ppk31 (SPBC725.06c)
• ppk32 (SPBP23A10.10)
• ppk33 (SPCC162.10)
• ppm1 (SPBP8B7.08c)
• ppr6 (SPCC11E10.04)
• qcr9 (SPCC1682.01)
• rad3 (SPBC216.05)
• sck2 (SPAC22E12.14c)
• sty1 (SPAC24B11.06c)
• vps15 (SPBC119.07)
• win1 (SPAC1006.09)
• wis4 (SPAC9G1.02)

Genotypes:

• atp12delta
• byr1delta
• byr2delta
• cbp6delta
• cdk11delta
• cdr1delta
• cek1delta
• cgs1delta
• cki2delta
• cki3delta
• cmk2delta
• cox5delta
• csk1delta
• hhp1delta
• idp1delta
• ksp1delta
• lsk1delta
• mak1delta
• mde3delta
• mpa1delta
• mph1delta
• pan302delta
• pck1delta
• pck2delta
• pit1delta
• pka1delta
• pom2delta
• por1delta
• pos5delta
• ppk16delta
• ppk1delta
• ppk22delta
• ppk30delta
• ppk31delta
• ppk32delta
• ppk33delta
• ppm1delta
• ppr6delta
• qcr9delta
• rad3delta
• sck2delta
• sty1delta
• vps15delta
• win1delta
• wis4delta

FYPO:0006969 - decreased cellular cytidine level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0006203 - decreased cellular dATP level

References:

• PMID:12062100
• PMID:19933844

Genes:

• cid13 (SPAC821.04c)
• iec1 (SPAC144.02)

Genotypes:

• cid13delta
• iec1delta

FYPO:0002571 - decreased cellular dGTP level

References:

• PMID:12062100
• PMID:22927644
• PMID:28640807

Genes:

• cid13 (SPAC821.04c)
• dcd1 (SPBC2G2.13c)
• trx1 (SPAC7D4.07c)

Genotypes:

• cid13delta
• dcd1delta
• trx1delta

FYPO:0005584 - decreased cellular diglyceride level

References:

• PMID:27053105
• PMID:36695178

Genes:

• mga2 (SPAC26H5.05)
• ned1 (SPAC1952.13)
• nem1 (SPBC3B8.10c)
• nem2 (SPBC902.03)

Genotypes:

• mga2delta
• ned1delta
• nem1delta
• nem2delta

FYPO:0007917 - decreased cellular dihydroceramide level

References:

• PMID:35008733

Genes:

• lac1 (SPBC3E7.15c)

Genotypes:

• lac1delta

FYPO:0006401 - decreased cellular dNTP level

References:

• PMID:28903048

Genes:

• set2 (SPAC29B12.02c)

Genotypes:

• set2delta

FYPO:0002572 - decreased cellular dTTP level

References:

• PMID:22927644

Genes:

• dcd1 (SPBC2G2.13c)

Genotypes:

• dcd1delta

FYPO:0002321 - decreased cellular ergosterol level

References:

• PMID:17276356
• PMID:22252817
• PMID:23145048
• PMID:40124504

Genes:

• apm1 (SPBP16F5.07)
• dap1 (SPAC25B8.01)
• erg5 (SPAC19A8.04)
• erg6 (SPBC16E9.05)
• gpa2 (SPAC23H3.13c)
• hmg1 (SPCC162.09c)
• oca3 (SPBC15C4.01c)
• pfl3 (SPBC947.04)
• rpl2001 (SPAC3A12.10)

Genotypes:

• apm1delta
• dap1-Y138F(aa)
• dap1delta
• erg5delta
• erg6delta
• gpa2delta
• hmg1-1(W234*)
• oca3delta
• pfl3delta
• rpl2001delta

FYPO:0002322 - decreased cellular FPP level

References:

• PMID:23145048

Genes:

• hmg1 (SPCC162.09c)

Genotypes:

• hmg1-1(W234*)

FYPO:0002323 - decreased cellular GGPP level

References:

• PMID:23145048

Genes:

• hmg1 (SPCC162.09c)

Genotypes:

• hmg1-1(W234*)

FYPO:0006144 - decreased cellular gluconate level

References:

• PMID:8898110

Genes:

• pka1 (SPBC106.10)

Genotypes:

• pka1delta

FYPO:0001563 - decreased cellular glutamate level

References:

• PMID:21307582
• PMID:37164017

Genes:

• atg22 (SPAC2G11.13)
• cox6 (SPAC1B2.04)

Genotypes:

• atg22delta
• cox6delta

FYPO:0001727 - decreased cellular glutamine level

References:

• PMID:14718525
• PMID:19734666

Genes:

• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)
• vma1 (SPAC343.05)

Genotypes:

• tsc1delta
• tsc2delta
• vma1delta

FYPO:0001570 - decreased cellular glutathione level during vegetative growth

References:

• PMID:16950927
• PMID:19180638
• PMID:21818608
• PMID:27005325

Genes:

• coq8 (SPBC2D10.18)
• gcs1 (SPAC22F3.10c)
• gsa1 (SPAC3F10.04)
• pgr1 (SPBC17A3.07)
• pgt1 (SPAC29B12.10c)

Genotypes:

• coq8delta
• gcs1delta
• gsa1delta
• pgr1+(wild type)[Knockdown]
• pgt1::KanMX4(disruption)

FYPO:0002812 - decreased cellular glycerol level

References:

• PMID:8825100

Genes:

• gpd1 (SPBC215.05)

Genotypes:

• gpd1delta

FYPO:0005458 - decreased cellular glycerol level during cellular response to non-ionic osmotic stress

References:

• PMID:24634168

Genes:

• gpd1 (SPBC215.05)
• pab1 (SPAC227.07c)

Genotypes:

• gpd1delta
• pab1-4(unknown)

FYPO:0002813 - decreased cellular glycerol level during cellular response to salt stress

References:

• PMID:7498541
• PMID:8704325
• PMID:8825100

Genes:

• gpd1 (SPBC215.05)
• wis1 (SPBC409.07c)

Genotypes:

• gpd1delta
• wis1delta

FYPO:0007187 - decreased cellular heme level

References:

• PMID:28377506

Genes:

• hem13 (SPAC222.11)

Genotypes:

• hem13-1(T263I aa)[Overexpression]

FYPO:0006699 - decreased cellular hercynylcysteine sulfoxide level during vegetative growth

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0001562 - decreased cellular histidine level

References:

• PMID:14718525
• PMID:18503766
• PMID:19734666
• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)
• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)
• vma1 (SPAC343.05)

Genotypes:

• atg22delta
• tsc1delta
• tsc2delta
• vma1delta

FYPO:0005630 - decreased cellular HMW SUMO conjugate level

References:

• PMID:21444718
• PMID:26221037
• PMID:38917328
• PMID:41330900

Genes:

• nse2 (SPAC16A10.06c)
• nup132 (SPAC1805.04)
• nup60 (SPCC285.13c)
• pli1 (SPAC1687.05)
• pmt3 (SPBC365.06)
• slx8 (SPBC3D6.11c)

Genotypes:

• nse2-RINGdelta(195-250 Δaa)
• nup132delta
• nup60delta
• pli1delta
• pmt3-D81R(aa)
• pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)
• slx8-29(unknown)

FYPO:0006889 - decreased cellular iron level

References:

• PMID:19915076

Genes:

• pcl1 (SPBC1683.10c)

Genotypes:

• pcl1delta

FYPO:0001617 - decreased cellular isoleucine level

References:

• PMID:18503766
• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)
• fnx1 (SPBC12C2.13c)
• fnx2 (SPBC3E7.06c)
• vma1 (SPAC343.05)

Genotypes:

• atg22delta
• fnx1delta
• fnx2delta
• vma1delta

FYPO:0006973 - decreased cellular L-glutamate methyl ester level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0002324 - decreased cellular lanosterol level

References:

• PMID:23145048
• PMID:27053105

Genes:

• erg5 (SPAC19A8.04)
• hmg1 (SPCC162.09c)
• mga2 (SPAC26H5.05)

Genotypes:

• erg5delta
• hmg1-1(W234*)
• mga2delta

FYPO:0001644 - decreased cellular lithium level

References:

• PMID:20699567

Genes:

• avt5 (SPBC1685.07c)

Genotypes:

• avt5delta

FYPO:0001619 - decreased cellular lysine level

References:

• PMID:18503766
• PMID:19734666
• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)
• fnx1 (SPBC12C2.13c)
• fnx2 (SPBC3E7.06c)
• vma1 (SPAC343.05)

Genotypes:

• atg22delta
• fnx1delta
• fnx2delta
• vma1delta

FYPO:0005591 - decreased cellular lysophosphatidylcholine level

References:

• PMID:27053105

Genes:

• mga2 (SPAC26H5.05)

Genotypes:

• mga2delta

FYPO:0005592 - decreased cellular lysophosphatidylethanolamine level

References:

• PMID:27053105

Genes:

• mga2 (SPAC26H5.05)

Genotypes:

• mga2delta

FYPO:0008261 - decreased cellular mannosylinositol phosphorylceramide level

References:

• PMID:20388730

Genes:

• scs7 (SPAC19G12.08)
• sur2 (SPBC887.15c)

Genotypes:

• scs7delta
• sur2delta

FYPO:0003769 - decreased cellular mtDNA level

References:

• PMID:12823554
• PMID:17868468
• PMID:20085751
• PMID:27664110
• PMID:28334955
• PMID:30658998
• PMID:31350787
• PMID:40124504

Genes:

• cce1 (SPAC25G10.02)
• grx5 (SPAPB2B4.02)
• mpa1 (SPAPB1E7.11c)
• msp1 (SPBC1718.06)
• mti2 (SPBC1271.15c)
• oca3 (SPBC15C4.01c)
• pog1 (SPCC24B10.22)

Genotypes:

• cce1+(wild type)[Overexpression]
• cce1-D230N(aa)
• cce1-D46N(aa)
• cce1delta
• cce1deltaSAP+delta244-258(1-35,244-258 Δaa)
• cce1deltaSAP(1-35 Δaa)
• grx5delta
• mpa1delta
• msp1-P300S(aa)
• mti2delta
• oca3delta
• pog1delta

FYPO:0010064 - decreased cellular NADPH level

References:

• PMID:41926382
• PMID:42024429

Genes:

• idp1 (SPAC6G10.08)
• pos5 (SPAC323.01c)

Genotypes:

• idp1delta
• pos5delta

FYPO:0003421 - decreased cellular nitric oxide level during cellular response to cadmium ion

References:

• PMID:24879348

Genes:

• mxr2 (SPBC216.04c)

Genotypes:

• mxr2+(wild type)[Overexpression]

FYPO:0003127 - decreased cellular nitric oxide level during vegetative growth

References:

• PMID:24313451
• PMID:24879348

Genes:

• mxr2 (SPBC216.04c)
• sdu1 (SPAPYUG7.06)

Genotypes:

• mug67+(wild type)[Overexpression]
• mxr2+(wild type)[Overexpression]

FYPO:0001564 - decreased cellular ornithine level

References:

• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)

Genotypes:

• atg22delta

FYPO:0006705 - decreased cellular pentose phosphate level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0004556 - decreased cellular phosphatidylcholine level

References:

• PMID:42562571
• PMID:9755189

Genes:

• cho1 (SPBC337.16)
• mga2 (SPAC26H5.05)

Genotypes:

• cho1delta
• mga2delta

FYPO:0001285 - decreased cellular phosphatidylethanolamine level

References:

• PMID:17905925

Genes:

• pps1 (SPCC1442.12)

Genotypes:

• pps1delta

FYPO:0000993 - decreased cellular phosphatidylinositol-3-phosphate level

References:

• PMID:7772832

Genes:

• pik3 (SPAC458.05)

Genotypes:

• pik3::ura4(disruption)

FYPO:0006775 - decreased cellular phosphatidylinositol-4-phosphate level

References:

• PMID:20123972

Genes:

• pik1 (SPAC22E12.16c)

Genotypes:

• pik1-delta117-198(aa)

FYPO:0007365 - decreased cellular phosphoenolpyruvate level

References:

• PMID:32319721

Genes:

• pyk1 (SPAC4H3.10c)

Genotypes:

• pyk1-T343A(aa)

FYPO:0005588 - decreased cellular phosphoinositide level

References:

• PMID:27053105

Genes:

• mga2 (SPAC26H5.05)

Genotypes:

• mga2delta

FYPO:0002829 - decreased cellular phytochelatin level

References:

• PMID:10368185
• PMID:1448066
• PMID:20937798

Genes:

• ade8 (SPBC14F5.09c)
• hmt1 (SPCC737.09c)
• pcs2 (SPAC3H1.10)

Genotypes:

• ade8.106(unknown)
• hmt1delta
• pcs2delta

FYPO:0008024 - decreased cellular polyphosphate level

References:

• PMID:35012333

Genes:

• asp1 (SPCC1672.06c)
• vtc4 (SPCC1322.14c)

Genotypes:

• asp1-D333A(aa)
• asp1-H397A(aa)
• asp1delta
• vtc4-Y22A,K26A,K30A(aa)

FYPO:0004150 - decreased cellular pyridoxamine 5'-phosphate level

References:

• PMID:15047724

Genes:

• plr1 (SPAC9E9.11)

Genotypes:

• plr1delta

FYPO:0004151 - decreased cellular pyridoxine level

References:

• PMID:15047724

Genes:

• plr1 (SPAC9E9.11)

Genotypes:

• plr1delta

FYPO:0002780 - decreased cellular reactive oxygen species level during vegetative growth

References:

• PMID:17530441
• PMID:17668038
• PMID:18182845
• PMID:19352039
• PMID:20563653
• PMID:20655879
• PMID:23456650
• PMID:24313451
• PMID:24879348
• PMID:31562247
• PMID:37787465

Genes:

• but1 (SPAC27D7.12c)
• cdc2 (SPBC11B10.09)
• dnm1 (SPBC12C2.08)
• ecl1 (SPCC70.12c)
• ecl2 (SPBP35G2.16c)
• ecl3 (SPBC8E4.12c)
• grx3 (SPCC1450.06c)
• grx4 (SPBC26H8.06)
• mpr1 (SPBC725.02)
• mxr2 (SPBC216.04c)
• sdu1 (SPAPYUG7.06)
• sty1 (SPAC24B11.06c)
• txl1 (SPBC577.08c)

Genotypes:

• but1+(wild type)[Overexpression]
• cdc2-3w(C67Y aa)
• dnm1delta
• ecl1+(wild type)[Overexpression]
• ecl2+(wild type)[Overexpression]
• ecl3+(wild type)[Overexpression]
• grx3+(wild type)[Overexpression]
• grx4+(wild type)[Overexpression]
• mpr1+(wild type)[Overexpression]
• mug67+(wild type)[Overexpression]
• mxr2+(wild type)[Overexpression]
• sty1delta
• txl1+(wild type)[Overexpression]

FYPO:0006972 - decreased cellular S-adenosyl-L-cysteine level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0006696 - decreased cellular S-adenosyl-L-homocysteine level during vegetative growth

References:

• PMID:30072439
• PMID:30240645

Genes:

• cwh43 (SPAC589.12)
• sam1 (SPBC14F5.05c)

Genotypes:

• cwh43-G753R(aa)
• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0006695 - decreased cellular S-adenosyl-L-methionine level during vegetative growth

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0006968 - decreased cellular SAICAR level

References:

• PMID:30072439

Genes:

• cwh43 (SPAC589.12)

Genotypes:

• cwh43-G753R(aa)

FYPO:0006704 - decreased cellular sedoheptulose-7-phosphate level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0002320 - decreased cellular squalene level

References:

• PMID:23145048

Genes:

• hmg1 (SPCC162.09c)

Genotypes:

• hmg1-1(W234*)

FYPO:0002234 - decreased cellular sterol ester level

References:

• PMID:22592553

Genes:

• ptl2 (SPAC1786.01c)

Genotypes:

• ptl2delta

FYPO:0001412 - decreased cellular sulfide level

References:

• PMID:10224084

Genes:

• sir1 (SPAC10F6.01c)

Genotypes:

• sir1delta

FYPO:0001560 - decreased cellular threonine level

References:

• PMID:14718525
• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)
• tsc1 (SPAC22F3.13)
• tsc2 (SPAC630.13c)

Genotypes:

• atg22delta
• tsc1delta
• tsc2delta

FYPO:0003460 - decreased cellular trehalose level during cellular response to oxidative stress

References:

• PMID:12855726

Genes:

• sty1 (SPAC24B11.06c)

Genotypes:

• sty1delta

FYPO:0003459 - decreased cellular trehalose level during cellular response to salt stress

References:

• PMID:12855726

Genes:

• sty1 (SPAC24B11.06c)

Genotypes:

• sty1delta

FYPO:0005585 - decreased cellular triglyceride level during vegetative growth

References:

• PMID:26990381
• PMID:27053105
• PMID:28282432
• PMID:36695178

Genes:

• dga1 (SPCC1235.15)
• mga2 (SPAC26H5.05)
• ned1 (SPAC1952.13)
• nem1 (SPBC3B8.10c)
• nem2 (SPBC902.03)
• plh1 (SPBC776.14)

Genotypes:

• dga1delta
• mga2delta
• ned1delta
• nem1delta
• nem2delta
• plh1delta

FYPO:0006703 - decreased cellular UDP level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0007291 - decreased cellular UDP-galactose level

References:

• PMID:19942659

Genes:

• gal7 (SPBPB2B2.10c)
• uge1 (SPBC365.14c)

Genotypes:

• gal7delta
• uge1delta

FYPO:0006701 - decreased cellular UMP level

References:

• PMID:30240645

Genes:

• sam1 (SPBC14F5.05c)

Genotypes:

• sam1-1(F367L aa)
• sam1-3(L292S,R299H aa)

FYPO:0001616 - decreased cellular valine level

References:

• PMID:19734666
• PMID:21307582

Genes:

• atg22 (SPAC2G11.13)
• vma1 (SPAC343.05)

Genotypes:

• atg22delta
• vma1delta

FYPO:0001534 - decreased cellular zinc level

References:

• PMID:18203864
• PMID:18637840
• PMID:24003116
• PMID:29529046

Genes:

• zhf1 (SPAC23C11.14)
• zrt1 (SPBC16D10.06)

Genotypes:

• zhf1delta
• zrt1-W141->stop(W141*)
• zrt1delta

FYPO:0003094 - decreased centromeric outer repeat transcript level

References:

• PMID:16797182
• PMID:19111658
• PMID:24095277
• PMID:24713849
• PMID:26518661
• PMID:28974540

Genes:

• alm1 (SPAC1486.04c)
• chp1 (SPAC18G6.02c)
• chp2 (SPBC16C6.10)
• clr1 (SPBC2D10.17)
• clr2 (SPAC1B3.17)
• clr3 (SPBC800.03)
• eri1 (SPBC30B4.08)
• leo1 (SPBC13E7.08c)
• mit1 (SPBP35G2.10)
• red1 (SPAC1006.03c)
• swi6 (SPAC664.01c)
• tri1 (SPBC29A10.09c)

Genotypes:

• alm1delta
• chp1delta
• chp2delta
• clr1delta
• clr2delta
• clr3delta
• eri1delta
• leo1delta
• mit1delta
• red1delta
• swi6delta
• tri1delta

FYPO:0004201 - decreased centromeric outer repeat transcript-derived siRNA level

References:

• PMID:16797182
• PMID:17310250
• PMID:17512405
• PMID:17948055
• PMID:18948543
• PMID:19362535
• PMID:20178743
• PMID:21436456
• PMID:21725325
• PMID:25274039
• PMID:26438724
• PMID:26443059
• PMID:27538348
• PMID:28541282
• PMID:41316862
• PMID:42420319

Genes:

• ago1 (SPCC736.11)
• arb1 (SPAC140.03)
• arb2 (SPAC13G7.07)
• cdc28 (SPBC19C2.01)
• chp1 (SPAC18G6.02c)
• cid12 (SPCC663.12)
• cid14 (SPAC12G12.13c)
• cid16 (SPAC17H9.01)
• clr4 (SPBC428.08c)
• dcr1 (SPCC188.13c)
• epe1 (SPCC622.16c)
• mlo3 (SPBC1D7.04)
• mms19 (SPAC1071.02)
• mug174 (SPCC1682.03c)
• pac1 (SPBC119.11c)
• pir2 (SPBC725.08)
• prp10 (SPAC27F1.09c)
• prp12 (SPAPJ698.03c)
• prp5 (SPBP22H7.07)
• rdp1 (SPAC6F12.09)
• rpb2 (SPAC23G3.01)
• saf1 (SPCC663.11)
• saf5 (SPAC1610.01)
• sde2 (SPAC31G5.18c)
• set3 (SPAC22E12.11c)
• sgf73 (SPCC126.04c)
• smd3 (SPBC19C2.14)
• swi6 (SPAC664.01c)
• tgs1 (SPAC2G11.15c)

Genotypes:

• ago1-D580A(aa)
• ago1-F276A(aa)
• ago1delta
• arb1delta
• arb2delta
• chp1-E23V,V24M(aa)
• chp1delta
• cid12delta
• cid14-DADA(D298A,D300A aa)
• cid14delta
• cid16delta
• clr4delta
• dcr1delta
• epe1delta
• mlo3-KA(K165A,K167A aa)
• mlo3delta
• mms19delta
• mug174delta
• pac1-A342T(aa)
• pir2-1(F165L,S316P aa)
• prp10-1(A1050V,S1058F aa)
• prp12-1(G3340A nt)
• prp5-1(unknown)
• prp8-1(unknown)
• rdp1delta
• rpb2-m203(N44Y aa)
• saf1delta
• saf5delta
• sde2delta
• set3delta
• sgf73delta
• smd3delta
• swi6delta
• tgs1-G154D(aa)
• tgs1delta

FYPO:0004441 - decreased cytosolic calcium level

References:

• PMID:21811607
• PMID:36200871

Genes:

• pkd2 (SPAC1F7.03)
• pmk1 (SPBC119.08)
• sid2 (SPAC24B11.11c)

Genotypes:

• pkd2+(wild type)[Knockdown]
• pmk1delta
• sid2-250(E314K aa)

FYPO:0006827 - decreased cytosolic zinc level

References:

• PMID:29529046

Genes:

• zrt1 (SPBC16D10.06)

Genotypes:

• zrt1delta

FYPO:0005476 - decreased filamentous actin level

References:

• PMID:21885283
• PMID:9459302

Genes:

• bzz1 (SPBC12C2.05c)
• myp2 (SPAC4A8.05c)

Genotypes:

• bzz1-deltaSH3(586-642 Δaa)
• myo3::ura4+

FYPO:0001195 - decreased galactomannan level

References:

• PMID:11016847
• PMID:18793338
• PMID:8887550

Genes:

• rga2 (SPAC26A3.09c)
• rho1 (SPAC1F7.04)
• yam8 (SPAC1F5.08c)

Genotypes:

• ehs1-1(P455S aa)
• rga2+(wild type)[Overexpression]
• rho1-G15V(aa)[Overexpression]
• yam8delta

FYPO:0001212 - decreased Glc1Man9GlcNAc level

References:

• PMID:9813085

Genes:

• alg6 (SPBC342.01c)

Genotypes:

• alg6delta

FYPO:0004713 - decreased level of amino acid biosynthesis gene mRNA during vegetative growth

References:

• PMID:18203864

Genes:

• zrt1 (SPBC16D10.06)

Genotypes:

• zrt1-W141->stop(W141*)

FYPO:0004714 - decreased level of amino acid import gene mRNA during vegetative growth

References:

• PMID:18203864

Genes:

• zrt1 (SPBC16D10.06)

Genotypes:

• zrt1-W141->stop(W141*)

FYPO:0005946 - decreased level of cell cycle regulated gene mRNA during vegetative growth

References:

• PMID:15195092

Genes:

• ace2 (SPAC6G10.12c)
• sep1 (SPBC4C3.12)

Genotypes:

• ace2delta
• sep1delta

FYPO:0004903 - decreased level of cell separation after cytokinesis gene mRNA during vegetative growth

References:

• PMID:15829570
• PMID:25015293
• PMID:25530312
• PMID:30102332

Genes:

• eaf1 (SPCC1223.10c)
• ebp1 (SPAC6G9.15c)
• ell1 (SPBP23A10.14c)
• mcs6 (SPBC19F8.07)
• pmh1 (SPBC776.18c)
• rpb7 (SPACUNK4.06c)
• spt20 (SPAC4D7.10c)
• spt7 (SPBC25H2.11c)
• spt8 (SPBC14C8.17c)

Genotypes:

• eaf1delta
• ebp1delta
• ell1delta
• mcs6-ts1(unknown)
• pmh1-26(Q17R,N23K,F47S,T56S,L63P,E70G,G95V,K256R aa)
• rpb7+(wild type)[Knockdown]
• spt20delta
• spt7delta
• spt8delta

FYPO:0005090 - decreased level of cytokinesis gene mRNA during vegetative growth

References:

• PMID:15829570

Genes:

• mcs6 (SPBC19F8.07)
• pmh1 (SPBC776.18c)

Genotypes:

• mcs6-ts1(unknown)
• pmh1-26(Q17R,N23K,F47S,T56S,L63P,E70G,G95V,K256R aa)

FYPO:0005826 - decreased level of generation of precursor metabolites and energy gene mRNA during vegetative growth

References:

• PMID:27886462

Genes:

• ppr10 (SPBC106.19)

Genotypes:

• ppr10::KanMX6(disruption)[Null]

FYPO:0003447 - decreased level of glycosylated protein in cell

References:

• PMID:7969124
• PMID:9839953

Genes:

• gma12 (SPCC736.04c)
• gmh3 (SPAC22E12.06c)
• srp54 (SPCC188.06c)

Genotypes:

• gma12::ura4+
• gmh3::LEU2+
• srp54+(wild type)[Knockdown]

FYPO:0006412 - decreased level of histone gene mRNA during mitotic S phase

References:

• PMID:17452352
• PMID:27901072

Genes:

• ams2 (SPCC290.04)

Genotypes:

• ams2-MZF(C375A,C378A aa)
• ams2delta

FYPO:0004906 - decreased level of histone gene mRNA during vegetative growth

References:

• PMID:23314747
• PMID:27901072

Genes:

• ams2 (SPCC290.04)
• teb1 (SPAC13G7.10)

Genotypes:

• ams2delta
• teb1-1(R184C aa)

FYPO:0005218 - decreased level of histone H2A in cell

References:

• PMID:26582768

Genes:

• abo1 (SPAC31G5.19)

Genotypes:

• abo1delta

FYPO:0003249 - decreased level of histone H3 at dh repeat

References:

• PMID:22291963
• PMID:26582768

Genes:

• abo1 (SPAC31G5.19)
• asf1 (SPCC663.05c)

Genotypes:

• abo1delta
• asf1-33(A16T,L61P,E119K,L121P,N156S,E180G aa)

FYPO:0004578 - decreased level of histone H3 in cell

References:

• PMID:23032292
• PMID:25398909
• PMID:25602522
• PMID:26582768
• PMID:39878217

Genes:

• abo1 (SPAC31G5.19)
• asf1 (SPCC663.05c)
• cay1 (SPBC2F12.12c)
• hip1 (SPBC31F10.13c)
• pob3 (SPBC609.05)

Genotypes:

• abo1delta
• asf1-AID(Conditional knock-out of Asf1 in presence of IAA)
• cay1delta
• hip1delta
• pob3delta

FYPO:0007324 - decreased level of histone H4 in cell

References:

• PMID:30992049
• PMID:39878217

Genes:

• asf1 (SPCC663.05c)
• hhf1 (SPAC1834.03c)
• hhf2 (SPBC8D2.03c)
• hhf3 (SPBC1105.12)
• vid21 (SPCC1795.08c)

Genotypes:

• asf1-AID(Conditional knock-out of Asf1 in presence of IAA)
• hhf1-KR(K6R,K9R,K13R,K17R aa)
• hhf2-KR(K6R,K9R,K13R,K17R aa)
• hhf3-KR(K6R,K9R,K13R,K17R aa)
• vid21+(wild type)[Knockdown]

FYPO:0005654 - decreased level of iron assimilation gene mRNA during vegetative growth

References:

• PMID:25806539

Genes:

• fra2 (SPAC8C9.11)
• grx4 (SPBC26H8.06)

Genotypes:

• fra2delta
• grx4-C172S(aa)
• grx4delta

FYPO:0004905 - decreased level of iron homeostasis gene mRNA during vegetative growth

References:

• PMID:23314747

Genes:

• teb1 (SPAC13G7.10)

Genotypes:

• teb1-1(R184C aa)

FYPO:0005368 - decreased level of iron ion starvation-induced proteins

References:

• PMID:19620282

Genes:

• hip1 (SPBC31F10.13c)
• slm9 (SPBC15D4.03)

Genotypes:

• hip1delta
• slm9delta

FYPO:0002012 - decreased level of iron ion starvation-repressed proteins

References:

• PMID:23115244

Genes:

• fxn1 (SPCC1183.03c)

Genotypes:

• fxn1delta

FYPO:0005580 - decreased level of lipid metabolism gene mRNA during cellular response to hypoxia

References:

• PMID:15797383
• PMID:27053105

Genes:

• mga2 (SPAC26H5.05)
• scp1 (SPBC3B9.15c)
• sre1 (SPBC19C2.09)

Genotypes:

• mga2delta
• scp1delta
• sre1delta

FYPO:0004880 - decreased level of lipid metabolism gene mRNA during vegetative growth

References:

• PMID:26366556
• PMID:38482739
• PMID:38780300
• PMID:39652606
• PMID:42562571

Genes:

• cbf11 (SPCC736.08)
• mga2 (SPAC26H5.05)

Genotypes:

• cbf11(DBM)(R318H aa)
• cbf11delta
• mga2-deltaPPPY(1041-1044 Δaa)
• mga2delta

FYPO:0004878 - decreased level of mitotically up-regulated gene mRNA during vegetative growth

References:

• PMID:25847133

Genes:

• sep1 (SPBC4C3.12)

Genotypes:

• sep1delta

FYPO:0004897 - decreased level of nitrogen starvation gene mRNA during vegetative growth

References:

• PMID:25102102

Genes:

• phx1 (SPAC32A11.03c)

Genotypes:

• phx1delta

FYPO:0004712 - decreased level of nucleotide metabolism gene mRNA during vegetative growth

References:

• PMID:18203864

Genes:

• zrt1 (SPBC16D10.06)

Genotypes:

• zrt1-W141->stop(W141*)

FYPO:0004971 - decreased level of stress responsive gene mRNA during cellular response to phosphate starvation

References:

• PMID:26345368

Genes:

• myo1 (SPBC146.13c)

Genotypes:

• myo1delta

FYPO:0005908 - decreased level of stress responsive gene mRNA during vegetative growth

References:

• PMID:24768994

Genes:

• opi10 (SPBC21H7.06c)

Genotypes:

• opi10delta

FYPO:0002775 - decreased level of sumoylated protein in cell

References:

• PMID:12597774
• PMID:15359282
• PMID:26537787
• PMID:28552615
• PMID:30348841

Genes:

• brc1 (SPBC582.05c)
• hus5 (SPAC30D11.13)
• nse6 (SPAC11E3.08c)
• pli1 (SPAC1687.05)
• pmt3 (SPBC365.06)
• rad31 (SPAC4C5.04)
• uba2 (SPBC16H5.03c)

Genotypes:

• brc1-T643A(aa)
• brc1delta
• hus5-L97F(aa)
• hus5-P123S(aa)
• hus5-P128S(aa)
• hus5.17(G253T nt)
• hus5.62(A129V aa)
• nse6delta
• pli1-C321S(aa)
• pli1delta
• pmt3-His6SUMO-L109K(aa)
• pmt3delta
• rad31-G56R(aa)
• uba2-Q553->stop(Q553*)
• uba2-R354H(aa)

FYPO:0004711 - decreased level of translation gene mRNA during vegetative growth

References:

• PMID:18203864
• PMID:23314747

Genes:

• teb1 (SPAC13G7.10)
• zrt1 (SPBC16D10.06)

Genotypes:

• teb1-1(R184C aa)
• zrt1-W141->stop(W141*)

FYPO:0005187 - decreased level of transport gene mRNA during vegetative growth

References:

• PMID:19546237
• PMID:29632066
• PMID:38780300

Genes:

• cbf11 (SPCC736.08)
• cut6 (SPAC56E4.04c)
• gad8 (SPCC24B10.07)
• mga2 (SPAC26H5.05)
• tor1 (SPBC30D10.10c)

Genotypes:

• cbf11(DBM)(R318H aa)
• cbf11delta
• cut6-promoter-mutant(G(-127)C,G(-125)C,G(-123)A,A(-122)G)[Knockdown]
• gad8delta
• mga2delta
• tor1delta

FYPO:0005226 - decreased level of ubiquitinated protein in cell

References:

• PMID:26518661
• PMID:27151298
• PMID:34674264
• PMID:35639710
• PMID:41330900

Genes:

• any1 (SPBC18H10.20c)
• dma1 (SPAC17G8.10c)
• htb1 (SPCC622.09)
• leo1 (SPBC13E7.08c)
• pcn1 (SPBC16D10.09)
• rad8 (SPAC13G6.01c)
• ubp12 (SPCC1494.05c)

Genotypes:

• can1-1(R175C aa)
• dma1-I194A(aa)
• htb1-K119R(K120R aa)
• leo1delta
• pcn1-K164R(aa)
• rad8delta
• ubp12+(wild type)[Overexpression]

FYPO:0005673 - decreased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate

References:

• PMID:27151298

Genes:

• ubp2 (SPAC328.06)

Genotypes:

• ubp2delta

FYPO:0008248 - decreased LTR-derived RNA level

References:

• PMID:25356590

Genes:

• ash2 (SPBC13G1.08c)
• sdc1 (SPCC18.11c)
• set1 (SPCC306.04c)
• shg1 (SPAC17G8.09)

Genotypes:

• ash2delta
• sdc1delta
• set1-F(set1-3xFLAG)
• set1-RRM1delta(RRM1 domain deletion)[Knockdown]
• set1-nSETdelta(nSET domain deletion)[Knockdown]
• shg1delta

FYPO:0001144 - decreased Man8GlcNAc level

References:

• PMID:16079177

Genes:

• mns1 (SPAC2E1P5.01c)

Genotypes:

• mns1delta

FYPO:0003694 - decreased mature 18S rRNA level

References:

• PMID:10947840
• PMID:16251348
• PMID:36423630
• PMID:37913773
• PMID:7596817
• PMID:9211981
• PMID:9693363

Genes:

• ani1 (SPBC1347.02)
• gar2 (SPAC140.02)
• grn1 (SPBC26H8.08c)
• mis3 (SPBC25B2.05)
• nuc1 (SPBC4C3.05c)
• tor2 (SPBC216.07c)

Genotypes:

• ani1delta
• gar2-S50A(aa)
• gar2::ura4+
• gar2delta
• grn1delta
• mis3-224(G188E aa)
• nuc1-632(unknown)
• tor2-L2048S(aa)

FYPO:0001137 - decreased mature 25S rRNA level

References:

• PMID:16251348
• PMID:21385875
• PMID:27667686
• PMID:36423630

Genes:

• ani1 (SPBC1347.02)
• grc3 (SPCC830.03)
• grn1 (SPBC26H8.08c)
• mdn1 (SPCC737.08)

Genotypes:

• ani1delta
• grc3-7(unknown)
• grn1delta
• mdn1-ts26(V3105A,I3280M,P3461S,S3916P,E3939K aa)

FYPO:0001138 - decreased mature 5.8S rRNA level

References:

• PMID:21385875

Genes:

• grc3 (SPCC830.03)

Genotypes:

• grc3-7(unknown)

FYPO:0002584 - decreased mature mitochondrial tRNA level

References:

• PMID:23928301
• PMID:29954949

Genes:

• trz2 (SPBC3D6.03c)

Genotypes:

• trz2-1(A623V aa)

FYPO:0006466 - decreased mature ncRNA level

References:

• PMID:29422501
• PMID:41974504

Genes:

• nup211 (SPCC162.08c)
• pof8 (SPAC17G6.17)
• rsm1 (SPCC1753.05)

Genotypes:

• nup211-1435*(L1435*)
• pof8delta
• rsm1delta

FYPO:0006470 - decreased mature rRNA level

References:

• PMID:38482739
• PMID:41258116

Genes:

• cbf11 (SPCC736.08)
• gad8 (SPCC24B10.07)
• leo1 (SPBC13E7.08c)
• sin1 (SPAPYUG7.02c)
• ste20 (SPBC12C2.02c)
• tor2 (SPBC216.07c)
• wat1 (SPBC21B10.05c)

Genotypes:

• cbf11delta
• gad8delta
• leo1delta
• sin1delta
• ste20delta
• tor2-L2048S(aa)
• wat1delta

FYPO:0002932 - decreased mature snoRNA level

References:

• PMID:20129053
• PMID:24081329

Genes:

• pab2 (SPBC16E9.12c)
• rrp6 (SPAC1F3.01)

Genotypes:

• pab2::ura4+[Null]
• pab2delta
• rrp6delta

FYPO:0004204 - decreased mature snRNA level

References:

• PMID:10445882
• PMID:1943699
• PMID:20400941
• PMID:26213367
• PMID:33754639

Genes:

• gem8 (SPBC16H5.15)
• mpn1 (SPAC23C11.10)
• pac1 (SPBC119.11c)
• smn1 (SPAC2G11.08c)
• snu2 (SPSNRNA.02)

Genotypes:

• gem8+(wild type)[Knockdown]
• mpn1delta
• pac1-A342T(aa)
• snu2delta1((-200)-(-123))
• snu2delta2((-220)-(-74))
• snu2delta3((-220)-(-54))
• snu2delta4((-220)-(-33))
• tdSMN(Ub-DHFRts-smn1)

FYPO:0002583 - decreased mature tRNA level during vegetative growth

References:

• PMID:28977649
• PMID:29330317
• PMID:31833215
• PMID:32841241
• PMID:35901126

Genes:

• rpc34 (SPCC290.02)
• sla1 (SPAC57A10.10c)
• tor2 (SPBC216.07c)
• trm6 (SPBC800.08)
• trm8 (SPCPB16A4.04c)

Genotypes:

• rpc34-hmt4(unknown)
• sla1delta
• tor2-L2048S(aa)
• trm6delta
• trm8delta

FYPO:0010112 - decreased mitochondrial NADP+ level

References:

• PMID:41926382

Genes:

• pos5 (SPAC323.01c)

Genotypes:

• pos5delta

FYPO:0010116 - decreased mitochondrial pre-mRNA level

References:

• PMID:38604460

Genes:

• mss116 (SPBC691.04)

Genotypes:

• mss116delta

FYPO:0003915 - decreased mitochondrial protein level

References:

• PMID:22349564
• PMID:23892058
• PMID:28334955
• PMID:29458562
• PMID:34119521
• PMID:38499131
• PMID:38499152
• PMID:38604460
• PMID:39289458

Genes:

• cbp6 (SPBC947.14c)
• lon1 (SPAC22F3.06c)
• mpa1 (SPAPB1E7.11c)
• mrf1 (SPAC2F7.17)
• mrh5 (SPBC25D12.06)
• mss116 (SPBC691.04)
• mss51 (SPAC25B8.04c)
• mtf2 (SPAC5D6.12)
• ppr10 (SPBC106.19)
• ppr2 (SPBC18H10.11c)
• shy1 (SPBC1215.01)

Genotypes:

• cbp6delta
• lon1delta
• mpa1delta
• mrf1delta
• mrh5-D261A(aa)
• mrh5-E262A(aa)
• mrh5delta
• mss116delta
• mss51delta
• mtf2::kanMX6(disruption)
• ppr10delta
• ppr10deltaPPR(253-322 Δaa)[Knockdown]
• ppr2delta
• shy1delta

FYPO:0003423 - decreased mitochondrial RNA level

References:

• PMID:17292401
• PMID:21357609
• PMID:28334955
• PMID:29458562
• PMID:34634819
• PMID:38499152
• PMID:39289458

Genes:

• cbp7 (SPBC28E12.04)
• cbp8 (SPAC22H10.09)
• mpa1 (SPAPB1E7.11c)
• mrh5 (SPBC25D12.06)
• mtf1 (SPAC1002.08c)
• mtf2 (SPAC5D6.12)
• pet127 (SPCC1183.04c)
• ppr10 (SPBC106.19)
• rpo41 (SPAC26H5.12)
• shy1 (SPBC1215.01)

Genotypes:

• cbp7delta
• cbp8delta
• mpa1delta
• mrh5-D261A(aa)
• mrh5-E262A(aa)
• mrh5delta
• mtf1delta
• mtf2::kanMX6(disruption)
• pet127+(wild type)[Overexpression]
• ppr10delta
• rpo41delta
• shy1delta

FYPO:0003103 - decreased mRNA-derived small RNA level

References:

• PMID:24095277
• PMID:25417108
• PMID:42420319

Genes:

• dcr1 (SPCC188.13c)
• pir2 (SPBC725.08)
• tgs1 (SPAC2G11.15c)
• tri1 (SPBC29A10.09c)

Genotypes:

• dcr1delta
• pir2-1(F165L,S316P aa)
• tgs1delta
• tri1delta

FYPO:0006625 - decreased phosphatidylinositol-4,5-bisphosphate level in plasma membrane

References:

• PMID:10950958
• PMID:29975157
• PMID:39239853
• PMID:39540318

Genes:

• cfr1 (SPAC6G9.12)
• duc1 (SPCC594.01)
• efr3 (SPCC794.08)
• its3 (SPAC19G12.14)

Genotypes:

• cfr1delta
• duc1delta
• efr3delta
• its3-1(G281D aa)

FYPO:0006628 - decreased phosphatidylinositol-4-phosphate level in plasma membrane

References:

• PMID:29975157
• PMID:37815455
• PMID:39110593

Genes:

• efr3 (SPCC794.08)
• its3 (SPAC19G12.14)
• lsb6 (SPAC343.19)
• pdr16 (SPCC23B6.04c)
• pik1 (SPAC22E12.16c)
• spo20 (SPAC3H8.10)

Genotypes:

• efr3delta
• its3-1(G281D aa)
• lsb6delta
• pdr16delta
• pik1-11(D718G,C796R,T803A aa)
• spo20delta

FYPO:0008133 - decreased phosphatidylinositol-4-phosphate level in the Golgi

References:

• PMID:37815455

Genes:

• pik1 (SPAC22E12.16c)

Genotypes:

• pik1-11(D718G,C796R,T803A aa)

FYPO:0004681 - decreased polyadenylated 5.8S rRNA level

References:

• PMID:16478992

Genes:

• cid14 (SPAC12G12.13c)

Genotypes:

• cid14delta

FYPO:0002937 - decreased pre-mRNA level

References:

• PMID:11739743
• PMID:21981922
• PMID:24081329
• PMID:27172183

Genes:

• mei4 (SPBC32H8.11)
• meu17 (SPBC14C8.05c)
• not3 (SPAC1B3.05)
• pab2 (SPBC16E9.12c)
• ppk29 (SPBC557.04)
• rpl3001 (SPAC9G1.03c)
• rpl3002 (SPAC1250.05)
• snp27 (SPCC162.01c)

Genotypes:

• mei4delta
• meu17delta
• not3delta
• pab2delta
• ppk29delta
• rpl30-2deltai(264-509 Δnt)
• rpl3001+(wild type)[Overexpression]
• rpl3001::kanMX6(disruption)[Null]
• rpl3001delta
• snp27delta

FYPO:0006748 - decreased pre-tRNA level during vegetative growth

References:

• PMID:29330317
• PMID:31294478
• PMID:31833215

Genes:

• lrs1 (SPAC26F1.13c)
• maf1 (SPAC31G5.12c)
• nrs1 (SPBC1773.10c)
• sen1 (SPAC6G9.10c)
• tor2 (SPBC216.07c)

Genotypes:

• lrs1-hmt(unknown)
• maf1-7A(S59A,S60A,S61A,S63A,S82A,S83A,S84A aa)
• nrs1-hmt1(unknown)
• sen1delta
• tor2-L2048S(aa)
• tor2-ts6(S550P,K710M aa)

FYPO:0008342 - decreased pre-tRNA or mature level during vegetative growth

References:

• PMID:38295128

Genes:

• tan1 (SPBC25H2.10c)
• trm8 (SPCPB16A4.04c)

Genotypes:

• tan1delta
• trm8delta

FYPO:0003681 - decreased protein level at centromere outer repeat heterochromatin

References:

• PMID:19117951
• PMID:20018856
• PMID:29866182

Genes:

• cut4 (SPBC106.09)
• cut9 (SPAC6F12.15c)
• hsp90 (SPAC926.04c)
• mas5 (SPBC1734.11)
• nuc2 (SPAC17C9.01c)
• snu4 (SPSNRNA.04)
• swi6 (SPAC664.01c)

Genotypes:

• cut4-(unknown)
• cut4-553(unknown)
• cut9-665(A535T aa)
• hsp90-A4(R33C aa)
• mas5delta
• nuc2-(unknown)
• prp13-1(G35A nt)
• swi6delta

FYPO:0006885 - decreased protein level at mitotic spindle

References:

• PMID:30463883

Genes:

• alp16 (SPCC4G3.19)
• mal3 (SPAC18G6.15)

Genotypes:

• alp16delta
• mal3delta

FYPO:0005102 - decreased protein level at silent mating-type cassette

References:

• PMID:19117951

Genes:

• cut4 (SPBC106.09)
• cut9 (SPAC6F12.15c)
• nuc2 (SPAC17C9.01c)

Genotypes:

• cut4-(unknown)
• cut9-665(A535T aa)
• nuc2-(unknown)

FYPO:0004124 - decreased protein level during cellular response to cadmium ion

References:

• PMID:12521310

Genes:

• gst3 (SPAC688.04c)

Genotypes:

• gst3--378--998((-998)-(-378))

FYPO:0003007 - decreased protein level during cellular response to caffeine

References:

• PMID:19672306

Genes:

• moe1 (SPAC637.07)

Genotypes:

• moe1delta

FYPO:0004451 - decreased protein level during cellular response to calcium ion

References:

• PMID:25081204

Genes:

• ckk2 (SPCC1919.01)
• cmk1 (SPACUNK12.02c)
• prz1 (SPAC4G8.13c)

Genotypes:

• ckk2delta
• cmk1delta
• prz1delta

FYPO:0005910 - decreased protein level during cellular response to endoplasmic reticulum stress

References:

• PMID:23066505
• PMID:32735772

Genes:

• ire1 (SPAC167.01)

Genotypes:

• ire1delta

FYPO:0003650 - decreased protein level during cellular response to glucose starvation

References:

• PMID:15529002
• PMID:16202243
• PMID:16258244
• PMID:17205051
• PMID:19940942
• PMID:25411338
• PMID:26443240
• PMID:34086083
• PMID:8832415

Genes:

• pap1 (SPAC1783.07c)
• rst2 (SPAC6F12.02)
• sds23 (SPBC646.13)
• ssp1 (SPCC297.03)
• sty1 (SPAC24B11.06c)
• wis1 (SPBC409.07c)

Genotypes:

• pap1delta
• rst2delta
• sds23delta
• ssp1-837(W337*)
• sty1-1(unknown)
• wis1-DD(S469D,T473D aa)
• wis1delta

FYPO:0003151 - decreased protein level during cellular response to heat

References:

• PMID:11238999
• PMID:19625445
• PMID:22328580
• PMID:24146635
• PMID:32075773
• PMID:38181050
• PMID:7796804

Genes:

• brl1 (SPCC1919.15)
• brl2 (SPCC970.10c)
• cdc2 (SPBC11B10.09)
• clr4 (SPBC428.08c)
• cpc2 (SPAC6B12.15)
• dhp1 (SPAC26A3.12c)
• htb1 (SPCC622.09)
• mas5 (SPBC1734.11)
• nxt3 (SPBP8B7.11)
• rho1 (SPAC1F7.04)
• set1 (SPCC306.04c)
• ubp3 (SPBP8B7.21)

Genotypes:

• brl1delta
• brl2delta
• cdc2-L7(P208S aa)
• clr4-W31G(aa)
• cpc2delta
• dhp1delta867-991(aa)
• htb1-K119R(K120R aa)
• mas5delta
• nxt3delta
• rho1-596(C17R aa)
• set1delta
• ubp3delta

FYPO:0001101 - decreased protein level during cellular response to hydrogen peroxide

References:

• PMID:12018855
• PMID:12080074
• PMID:14633985
• PMID:15650694
• PMID:17668038
• PMID:19672306
• PMID:22245228
• PMID:23874237
• PMID:26567340

Genes:

• atf1 (SPBC29B5.01)
• csx1 (SPAC17A2.09c)
• ctu2 (SPBC19C2.13c)
• elp3 (SPAC29A4.20)
• gst1 (SPCC191.09c)
• moe1 (SPAC637.07)
• pap1 (SPAC1783.07c)
• sty1 (SPAC24B11.06c)
• tpx1 (SPCC576.03c)
• trm112 (SPAC31A2.02)
• trm9 (SPAC13D6.03c)
• trx1 (SPAC7D4.07c)

Genotypes:

• atf1delta
• csx1delta
• ctu2delta
• elp3delta
• gst1--770--1088((-1088)-(-770))
• moe1delta
• pap1delta
• sty1delta
• tpx1(1-181)(181-192 Δaa)
• tpx1-C169S(aa)
• tpx1delta
• trm112delta
• trm9delta
• trx1-promoter(-1--987)((-987)-(-1))
• trx1delta

FYPO:0004194 - decreased protein level during cellular response to hydroxyurea

References:

• PMID:10947840
• PMID:11715017
• PMID:15173168
• PMID:15347659
• PMID:16252005
• PMID:26912660
• PMID:9572736

Genes:

• cds1 (SPCC18B5.11c)
• gad8 (SPCC24B10.07)
• mis3 (SPBC25B2.05)
• mrc1 (SPAC694.06c)
• rad3 (SPBC216.05)
• tor1 (SPBC30D10.10c)

Genotypes:

• cds1-H81A(aa)
• cds1-I84A(aa)[Knockdown]
• cds1-N107A(aa)
• cds1-R64A(aa)
• cds1-S78A(aa)
• cds1::ura4(disruption)
• cds1delta
• gad8delta
• mis3-224(G188E aa)
• mrc1delta
• rad3-136(unknown)
• rad3::ura4+(disruption)
• rad3delta
• tor1delta

FYPO:0001274 - decreased protein level during cellular response to hypoxia

References:

• PMID:22017871
• PMID:24327658
• PMID:29083304

Genes:

• hhp2 (SPAC23C4.12)
• nro1 (SPCC4B3.07)
• ofd1 (SPBC6B1.08c)
• rps23 (SPAC23C11.02c)
• rps2302 (SPBP4H10.13)
• tom70 (SPAC6B12.12)

Genotypes:

• hhp2+(wild type)[Overexpression]
• nro1-A11D(aa)
• nro1-G8D(aa)
• nro1-P6D(aa)
• nro1delta
• ofd1-H142A(aa)
• rps2302-G6D(aa)
• rps2302delta
• rps23delta
• tom70+(wild type)[Overexpression]

FYPO:0004190 - decreased protein level during cellular response to ionizing radiation

References:

• PMID:16252005

Genes:

• chk1 (SPCC1259.13)

Genotypes:

• chk1delta

FYPO:0007826 - decreased protein level during cellular response to leucine starvation

References:

• PMID:33534698

Genes:

• gcn1 (SPAC18G6.05c)
• tif211 (SPAC3G9.09c)

Genotypes:

• gcn1delta
• tif211-S52A(aa)

FYPO:0004007 - decreased protein level during cellular response to menadione

References:

• PMID:12018855
• PMID:15135546
• PMID:15529002
• PMID:16554715
• PMID:17668038

Genes:

• gsa1 (SPAC3F10.04)
• pap1 (SPAC1783.07c)
• trr1 (SPBC3F6.03)
• trx1 (SPAC7D4.07c)

Genotypes:

• gsa1--365--234((-365)-(-234))
• pap1delta
• trr1-pYUTR40((-499)-(-186))
• trx1-promoter(-1--987)((-987)-(-1))

FYPO:0004037 - decreased protein level during cellular response to mercury ion

References:

• PMID:15135546

Genes:

• pap1 (SPAC1783.07c)

Genotypes:

• pap1delta

FYPO:0003143 - decreased protein level during cellular response to methyl methanesulfonate

References:

• PMID:12514100

Genes:

• chk1 (SPCC1259.13)
• rad17 (SPAC14C4.13)
• rad3 (SPBC216.05)
• rad9 (SPAC664.07c)

Genotypes:

• chk1delta
• rad17delta
• rad3delta
• rad9delta

FYPO:0003651 - decreased protein level during cellular response to nitrosative stress

References:

• PMID:15052323
• PMID:16202243
• PMID:17473896
• PMID:17725619
• PMID:19940942
• PMID:20563653
• PMID:22279963

Genes:

• pap1 (SPAC1783.07c)

Genotypes:

• pap1delta

FYPO:0007523 - decreased protein level during cellular response to oxidative stress

References:

• PMID:19625445

Genes:

• cpc2 (SPAC6B12.15)

Genotypes:

• cpc2delta

FYPO:0003930 - decreased protein level during cellular response to salt stress

References:

• PMID:11751918
• PMID:15629716
• PMID:16258240
• PMID:19625445

Genes:

• atf1 (SPBC29B5.01)
• cpc2 (SPAC6B12.15)
• pap1 (SPAC1783.07c)
• srk1 (SPCC1322.08)

Genotypes:

• atf1delta
• cpc2-R36D,K38E(aa)
• cpc2delta
• pap1delta
• srk1delta

FYPO:0007053 - decreased protein level during cellular response to zinc ion starvation

References:

• PMID:31239353

Genes:

• pho8 (SPBC14F5.13c)

Genotypes:

• pho8-m1(D311A,H315A aa)[Null]

FYPO:0004156 - decreased protein level during mitosis

References:

• PMID:26882497

Genes:

• mph1 (SPBC106.01)

Genotypes:

• mph1-kd(D459A aa)

FYPO:0005933 - decreased protein level during mitotic G1 phase

References:

• PMID:19487461
• PMID:7796804
• PMID:8521500

Genes:

• cdc10 (SPBC336.12c)

Genotypes:

• cdc10-129(T429A aa)
• cdc10-V50(H362Y aa)

FYPO:0006288 - decreased protein level during mitotic G2 phase

References:

• PMID:8521500

Genes:

• cdc25 (SPAC24H6.05)

Genotypes:

• cdc25-22(C532Y aa)

FYPO:0004193 - decreased protein level during mitotic S phase

References:

• PMID:16252005
• PMID:28903048
• PMID:8521500

Genes:

• cdc20 (SPBC25H2.13c)
• rad3 (SPBC216.05)
• set2 (SPAC29B12.02c)

Genotypes:

• cdc20-M10(unknown)
• rad3delta
• set2delta

FYPO:0007067 - decreased protein level during stress response to zinc ion

References:

• PMID:31239353

Genes:

• pho8 (SPBC14F5.13c)

Genotypes:

• pho8delta

FYPO:0001324 - decreased protein level during vegetative growth

References:

• PMID:10473641
• PMID:10503538
• PMID:10588653
• PMID:10905343
• PMID:11121040
• PMID:11160827
• PMID:11606526
• PMID:11751918
• PMID:12080074
• PMID:12456722
• PMID:12521308
• PMID:12589433
• PMID:12631727
• PMID:12668659
• PMID:12697806
• PMID:12931193
• PMID:14503856
• PMID:15052323
• PMID:15135546
• PMID:15177031
• PMID:15194814
• PMID:15335873
• PMID:15367656
• PMID:15507118
• PMID:15765057
• PMID:15797383
• PMID:15829570
• PMID:16252005
• PMID:16258240
• PMID:16291723
• PMID:16299000
• PMID:16317047
• PMID:16421249
• PMID:16428807
• PMID:16554715
• PMID:16950791
• PMID:17189249
• PMID:17205051
• PMID:17261596
• PMID:17473896
• PMID:17668038
• PMID:18062930
• PMID:18065650
• PMID:18272791
• PMID:18276645
• PMID:18414064
• PMID:18474252
• PMID:18761674
• PMID:18782833
• PMID:18793338
• PMID:18849471
• PMID:19279143
• PMID:19330768
• PMID:19417002
• PMID:19422421
• PMID:19625445
• PMID:19948484
• PMID:20164182
• PMID:20974849
• PMID:21324894
• PMID:22042869
• PMID:22065639
• PMID:22281223
• PMID:22727667
• PMID:22768388
• PMID:22976295
• PMID:23051734
• PMID:23080121
• PMID:23091701
• PMID:23133674
• PMID:23260662
• PMID:23349636
• PMID:23349808
• PMID:23442800
• PMID:23576550
• PMID:23690545
• PMID:23907979
• PMID:23934889
• PMID:23956636
• PMID:23977061
• PMID:23980030
• PMID:24127216
• PMID:24161933
• PMID:24316795
• PMID:24327658
• PMID:24451546
• PMID:24478458
• PMID:24798735
• PMID:24876389
• PMID:24945319
• PMID:25015293
• PMID:25245948
• PMID:25356590
• PMID:2537310
• PMID:25398909
• PMID:25473118
• PMID:25487150
• PMID:2569363
• PMID:26221037
• PMID:26567340
• PMID:26689777
• PMID:26746798
• PMID:26882497
• PMID:2690071
• PMID:26912660
• PMID:27191590
• PMID:27350684
• PMID:27398807
• PMID:27538348
• PMID:27618268
• PMID:27736299
• PMID:27898700
• PMID:28821619
• PMID:29084823
• PMID:29699848
• PMID:29735745
• PMID:29866182
• PMID:30044717
• PMID:30228203
• PMID:30240645
• PMID:30862564
• PMID:30992049
• PMID:31030285
• PMID:31072933
• PMID:31332096
• PMID:31538680
• PMID:31553675
• PMID:31927482
• PMID:32053662
• PMID:32915139
• PMID:33137104
• PMID:33225241
• PMID:33574613
• PMID:34402513
• PMID:34731638
• PMID:34910579
• PMID:35082773
• PMID:35171902
• PMID:35320724
• PMID:35536002
• PMID:37200372
• PMID:37913773
• PMID:37970674
• PMID:38181050
• PMID:38272226
• PMID:38499131
• PMID:38499152
• PMID:38917328
• PMID:39476757
• PMID:39509469
• PMID:40124504
• PMID:40402811
• PMID:40427588
• PMID:41201383
• PMID:41501458
• PMID:42562571
• PMID:7769002
• PMID:8387358
• PMID:8389306
• PMID:8824587
• PMID:9524127
• PMID:9571240
• PMID:9857180
• PMID:9914167

Genes:

• ace2 (SPAC6G10.12c)
• ada2 (SPCC24B10.08c)
• alm1 (SPAC1486.04c)
• alp1 (SPBC11C11.04c)
• alp11 (SPAC13D6.05)
• any1 (SPBC18H10.20c)
• aph1 (SPCC4G3.02)
• arp2 (SPAC11H11.06)
• art1 (SPBC19G7.08c)
• asf1 (SPCC663.05c)
• ash2 (SPBC13G1.08c)
• asp1 (SPCC1672.06c)
• atf1 (SPBC29B5.01)
• blt1 (SPBC1A4.05)
• bqt3 (SPCC594.07c)
• brl1 (SPCC1919.15)
• brl2 (SPCC970.10c)
• bub3 (SPAC23H3.08c)
• cam1 (SPAC3A12.14)
• cay1 (SPBC2F12.12c)
• cbp1 (SPBC1105.04c)
• cdc12 (SPAC1F5.04c)
• cdc13 (SPBC582.03)
• cdc2 (SPBC11B10.09)
• cdc25 (SPAC24H6.05)
• cdc48 (SPAC1565.08)
• cdr1 (SPAC644.06c)
• cdr2 (SPAC57A10.02)
• cds1 (SPCC18B5.11c)
• cdt2 (SPAC17H9.19c)
• cgs1 (SPAC8C9.03)
• chp1 (SPAC18G6.02c)
• clc1 (SPBC9B6.08)
• cpc2 (SPAC6B12.15)
• csk1 (SPAC1D4.06c)
• csx1 (SPAC17A2.09c)
• ctu1 (SPBC2G5.03)
• dea2 (SPBC1198.02)
• dis2 (SPBC776.02c)
• dlc1 (SPAC1805.08)
• efr3 (SPCC794.08)
• elp3 (SPAC29A4.20)
• elp6 (SPBC3H7.10)
• gad8 (SPCC24B10.07)
• gcn5 (SPAC1952.05)
• gef2 (SPAC31A2.16)
• ggt1 (SPAC664.09)
• git3 (SPCC1753.02c)
• grx1 (SPAC4F10.20)
• hcn1 (SPAC23C11.12)
• hhp2 (SPAC23C4.12)
• hip1 (SPBC31F10.13c)
• hip3 (SPBC31F10.14c)
• hsp90 (SPAC926.04c)
• hst2 (SPCC132.02)
• htb1 (SPCC622.09)
• hul6 (SPAC12B10.01c)
• hus1 (SPAC20G4.04c)
• imp2 (SPBC11C11.02)
• int6 (SPBC646.09c)
• ksg1 (SPCC576.15c)
• lam2 (SPBC1778.05c)
• lem2 (SPAC18G6.10)
• leo1 (SPBC13E7.08c)
• lkh1 (SPAC1D4.11c)
• lsd1 (SPBC146.09c)
• mad1 (SPBC3D6.04c)
• mad2 (SPBC20F10.06)
• mad3 (SPCC1795.01c)
• mas5 (SPBC1734.11)
• mat1-Mc (SPBC23G7.09)
• mcm2 (SPBC4.04c)
• mcm7 (SPBC25D12.03c)
• mcs4 (SPBC887.10)
• mcs6 (SPBC19F8.07)
• mga2 (SPAC26H5.05)
• mob2 (SPCC970.04c)
• moe1 (SPAC637.07)
• mre11 (SPAC13C5.07)
• mrh5 (SPBC25D12.06)
• mtf2 (SPAC5D6.12)
• mti2 (SPBC1271.15c)
• mtl2 (SPAC11G7.01)
• mtq2 (SPAC323.05c)
• myo52 (SPCC1919.10c)
• nap1 (SPCC364.06)
• ngg1 (SPBC28F2.10c)
• npr2 (SPAC23H3.03c)
• npr3 (SPBC543.04)
• nrd1 (SPAC2F7.11)
• nsp1 (SPAC26A3.15c)
• nuc1 (SPBC4C3.05c)
• nup124 (SPAC30D11.04c)
• nup132 (SPAC1805.04)
• nup184 (SPAP27G11.10c)
• nup186 (SPCC290.03c)
• nup189 (SPAC1486.05)
• nup45 (SPAC22G7.09c)
• nup60 (SPCC285.13c)
• nup61 (SPCC18B5.07c)
• nup97 (SPCC1620.11)
• oca3 (SPBC15C4.01c)
• orc5 (SPBC646.14c)
• pab1 (SPAC227.07c)
• paf1 (SPAC664.03)
• pap1 (SPAC1783.07c)
• pcf1 (SPBC29A10.03c)
• pcr1 (SPAC21E11.03c)
• pdk1 (SPBC1778.10c)
• pfd1 (SPBC1D7.01)
• pfd3 (SPAC3H8.07c)
• php4 (SPBC16E9.01c)
• pim1 (SPBC557.03c)
• pka1 (SPBC106.10)
• pmh1 (SPBC776.18c)
• pob3 (SPBC609.05)
• pol1 (SPAC3H5.06c)
• pom1 (SPAC2F7.03c)
• ppa1 (SPAC823.15)
• ppa2 (SPBC16H5.07c)
• ppk32 (SPBP23A10.10)
• ppr2 (SPBC18H10.11c)
• prf1 (SPBC651.09c)
• psm1 (SPBC29A10.04)
• psm3 (SPAC10F6.09c)
• pyp1 (SPAC26F1.10c)
• rad1 (SPAC1952.07)
• rad24 (SPAC8E11.02c)
• rad3 (SPBC216.05)
• rad9 (SPAC664.07c)
• rap1 (SPBC1778.02)
• rbd2 (SPCC790.03)
• red1 (SPAC1006.03c)
• rga2 (SPAC26A3.09c)
• rga4 (SPBC28E12.03)
• rga6 (SPBC354.13)
• rga7 (SPBC23G7.08c)
• rgf1 (SPCC645.07)
• rhp6 (SPAC18B11.07c)
• rna14 (SPAC6F12.17)
• rnc1 (SPCC757.09c)
• rng8 (SPAC4H3.14c)
• rng9 (SPBP8B7.02)
• rpb3 (SPCC1442.10c)
• rpb4 (SPBC337.14)
• rpb7 (SPACUNK4.06c)
• rrf1 (SPBC1709.09)
• sal3 (SPCC1840.03)
• sam1 (SPBC14F5.05c)
• sbg1 (SPBP22H7.03)
• scp1 (SPBC3B9.15c)
• sdc1 (SPCC18.11c)
• sds22 (SPAC4A8.12c)
• sds23 (SPBC646.13)
• sep1 (SPBC4C3.12)
• set1 (SPCC306.04c)
• set3 (SPAC22E12.11c)
• shf1 (SPAC22F8.12c)
• shg1 (SPAC17G8.09)
• slm9 (SPBC15D4.03)
• slp1 (SPAC821.08c)
• sls1 (SPAP8A3.14c)
• smi1 (SPBC30D10.17c)
• smn1 (SPAC2G11.08c)
• sod1 (SPAC821.10c)
• spf1 (SPCC594.05c)
• spo14 (SPBC3H7.01)
• spp1 (SPAC6B12.10c)
• spt20 (SPAC4D7.10c)
• sre1 (SPBC19C2.09)
• srk1 (SPCC1322.08)
• srw1 (SPAC144.13c)
• ssb1 (SPBC660.13c)
• ssb3 (SPCC23B6.05c)
• ssp2 (SPCC74.03c)
• ste20 (SPBC12C2.02c)
• sty1 (SPAC24B11.06c)
• suc1 (SPBC1734.14c)
• swd1 (SPAC23H3.05c)
• swd2 (SPBC18H10.06c)
• swd22 (SPAC824.04)
• swd3 (SPBC354.03)
• swi1 (SPBC216.06c)
• swi3 (SPBC30D10.04)
• tbc1 (SPAC328.08c)
• tel2 (SPAC458.03)
• tip1 (SPAC3C7.12)
• tls1 (SPAC1D4.01)
• tom70 (SPAC6B12.12)
• tor1 (SPBC30D10.10c)
• tor2 (SPBC216.07c)
• trm112 (SPAC31A2.02)
• trm9 (SPAC13D6.03c)
• trr1 (SPBC3F6.03)
• trx2 (SPBC12D12.07c)
• tsn1 (SPAC30.03c)
• ubc11 (SPCC1259.15c)
• wat1 (SPBC21B10.05c)
• wee1 (SPCC18B5.03)
• win1 (SPAC1006.09)
• wis1 (SPBC409.07c)
• wis4 (SPAC9G1.02)
• wsc1 (SPBC30B4.01c)
• ync13 (SPAC11E3.02c)
• zas1 (SPBC1198.04c)
• zfs1 (SPBC1718.07c)