Phenotype ontology term - FYPO:0001425 - abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication
Term summary
- ID
- FYPO:0001425
- Name
- abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication
- Ontology or CV name
- Phenotype
- Definition
- A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome.
Annotation
Multi-locus phenotype
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- cdc10-129(T429A aa) cdc18+(wild type)[Overexpression]
- cdc11-(unknown) cut1-(unknown)
- cdc11-123(R947H,T1041I aa) cut1-645(unknown)
- cdc13+(wild type)[Overexpression] cdc18deltaCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa)[Overexpression]
- cdc18+(wild type)[Overexpression] cdc25-22(C532Y aa)
- cdc18+(wild type)[Overexpression] cdt1+(wild type)[Overexpression]
- cdc18+(wild type)[Overexpression] orp2-T4A(T8A,T21A,T26A,T29A aa)
- cdc18-C(150-577)(1-149 Δaa)[Overexpression] cdt1+(wild type)[Overexpression]
- cdc18deltaCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa) cdt1-S360A(aa)[Knockdown]
- cdc18deltaCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa) cdt1-S360A(aa)[Overexpression]
- cdc25-22(C532Y aa) rum1-OP(pREP3X inducible overexpression)
- cig1delta rum1+(wild type)[Overexpression]
- cig2delta rum1+(wild type)[Overexpression]
- pop1delta pop2delta
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Single locus phenotype
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