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Phenotype ontology term - FYPO:0001645 - decreased protein-protein interaction

Term summary

ID
FYPO:0001645
Name
decreased protein-protein interaction
Ontology or CV name
Phenotype
Definition
A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes.

Parents

Annotation

Multi-locus phenotype

FYPO:0001645 - decreased protein-protein interaction

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FYPO:0005784 - decreased extent and duration of protein-protein interaction

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Single locus phenotype

FYPO:0001645 - decreased protein-protein interaction

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FYPO:0002656 - decreased actin filament binding

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FYPO:0005784 - decreased extent and duration of protein-protein interaction

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FYPO:0008059 - decreased K48-linked polyubiquitin binding

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FYPO:0007173 - decreased mitotic checkpoint complex binding

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FYPO:0004227 - decreased nucleosome binding

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FYPO:0005142 - decreased proteasome core complex binding

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FYPO:0003207 - decreased protein-protein interaction during cellular response to hydrogen peroxide

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FYPO:0005294 - decreased protein-protein interaction during cellular response to hydroxyurea

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FYPO:0005293 - decreased protein-protein interaction during cellular response to methyl methanesulfonate

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FYPO:0003206 - decreased protein-protein interaction during cellular response to salt stress

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FYPO:0005546 - decreased protein-protein interaction during mitotic S phase

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FYPO:0003634 - decreased U1 snRNP binding

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FYPO:0003636 - decreased U2 snRNP binding

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