Phenotype ontology term - FYPO:0003088 - abnormal replication fork arrest

Term summary

ID: FYPO:0003088
Name: abnormal replication fork arrest
Ontology or CV name: Phenotype
Definition: A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest is abnormal.

Parents

is_a regulation phenotype during vegetative growth
is_a DNA metabolism phenotype during vegetative growth
is_a abnormal cellular process during vegetative growth

Annotation

Single locus phenotype

FYPO:0003088 - abnormal replication fork arrest

References:

Genes:

Genotypes:

FYPO:0006603 - decreased replication fork arrest at RTS1 barrier

References:

Genes:

Genotypes:

FYPO:0006604 - decreased replication fork arrest at tRNA locus

References:

PMID:26201080

Genes:

mrc1 (SPAC694.06c)

Genotypes:

mrc1delta

FYPO:0007679 - increased replication fork arrest at RTS1 barrier

References:

PMID:33568651

Genes:

rtf1 (SPAC22F8.07c)

Genotypes:

rtf1+(wild type)[Overexpression]

FYPO:0003922 - increased replication fork arrest at tRNA locus

References:

PMID:22426534

Genes:

pfh1 (SPBC887.14c)

Genotypes:

pfh1+(wild type)[Knockdown]