Phenotype ontology term - FYPO:0003814 - abolished response to S-phase DNA damage checkpoint signaling
Term summary
- ID
- FYPO:0003814
- Name
- abolished response to S-phase DNA damage checkpoint signaling
- Ontology or CV name
- Phenotype
- Definition
- A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) does not occur. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.
Annotation
Single locus phenotype
References:
Genes:
Genotypes:
