Phenotype ontology term - FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

Term summary

ID

FYPO:0003815

Name

decreased response to S-phase DNA damage checkpoint signaling

Ontology or CV name

Phenotype

Definition

A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is decreased. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

• is_a abnormal S-phase DNA damage checkpoint

Annotation