Phenotype ontology term - FYPO:0003858 - sensitive to etoposide
Term summary
- ID
- FYPO:0003858
- Name
- sensitive to etoposide
- Ontology or CV name
- Phenotype
- Definition
- A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to etoposide. Cells stop growing (and may die) at a concentration of etoposide that allows wild type cells to grow.
Annotation
Multi-locus phenotype
References:
Genes:
Genotypes:
Single locus phenotype
References:
Genes:
Genotypes:
- SPBC26H8.13c+(wild type)[Overexpression]
- ctp1delta
- cul4+(wild type)[Overexpression]
- dbl8delta
- dbp5+(wild type)[Overexpression]
- kex1+(wild type)[Overexpression]
- mre11delta
- mug110+(wild type)[Overexpression]
- nvj2+(wild type)[Overexpression]
- pat1+(wild type)[Overexpression]
- pdr16+(wild type)[Overexpression]
- pfs2+(wild type)[Overexpression]
- pmd1delta
- psy1+(wild type)[Overexpression]
- rad50delta
- rad51+(wild type)[Overexpression]
- rad52+(wild type)[Overexpression]
- rrp2-DEAA(D539A,E540A aa)
- rrp2-K422A(aa)
- rrp2-SIM(1-6)*(VIALK100AAAAK,ITIDV143ATADA,VIVVS186AAAAS,LPVLS236APAAS,PISLS285AASAS,VILPG308AAAPG aa)
- rrp2-SIM3*+5*(V186A,I187A,V188A,V189A,P285A,I286A,L288A aa)
- rrp2delta
- rrp2deltaN360(1-360 Δaa)
- top2+(wild type)[Overexpression]
- ucp3+(wild type)[Overexpression]