Phenotype ontology term - FYPO:0003893 - abolished incorporation of ATP opposite 8-oxo-dG

Term summary

ID

FYPO:0003893

Name

abolished incorporation of ATP opposite 8-oxo-dG

Ontology or CV name

Phenotype

Definition

A cellular process phenotype in which the insertion of ATP opposite an 8-oxo-7,8-dihydroguanosine (8oxodG) residue in DNA does not occur. Normally, if a guanosine residue is damaged to form 8oxodG, ATP can be misincorporated into the opposite strand to form an 8oxodG:AMP mispair that is subsequently removed.

Parents

• is_a abnormal error-prone translesion synthesis

Annotation