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Phenotype ontology term - FYPO:0004142 - decreased RNA polymerase II proximal promoter sequence-specific DNA binding

Term summary

ID
FYPO:0004142
Name
decreased RNA polymerase II proximal promoter sequence-specific DNA binding
Ontology or CV name
Phenotype
Definition
A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.

Parents

Annotation

Single locus phenotype

FYPO:0004142 - decreased RNA polymerase II proximal promoter sequence-specific DNA binding

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