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Phenotype ontology term - FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

Term summary

ID
FYPO:0004259
Name
abolished mitotic G2 DNA damage checkpoint
Ontology or CV name
Phenotype
Definition
A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic G2 DNA damage checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.

Parents

Annotation

Multi-locus phenotype

FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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Single locus phenotype

FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0007247 - abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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