Phenotype ontology term - FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

Term summary

ID

FYPO:0004372

Name

decreased response to mitotic G2 DNA damage checkpoint signaling

Ontology or CV name

Phenotype

Definition

A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the mitotic G2 DNA damage checkpoint is decreased. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

• is_a abnormal mitotic G2 DNA damage checkpoint

Annotation