Phenotype ontology term - FYPO:0004373 - abnormal mitotic G2 DNA damage checkpoint
Term summary
- ID
- FYPO:0004373
- Name
- abnormal mitotic G2 DNA damage checkpoint
- Ontology or CV name
- Phenotype
- Definition
- A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is abnormal. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.
Annotation
Multi-locus phenotype
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Single locus phenotype
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