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Phenotype ontology term - FYPO:0004373 - abnormal mitotic G2 DNA damage checkpoint

Term summary

ID
FYPO:0004373
Name
abnormal mitotic G2 DNA damage checkpoint
Ontology or CV name
Phenotype
Definition
A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is abnormal. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.

Parents

Annotation

Multi-locus phenotype

FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0004870 - decreased duration of mitotic G2 DNA damage checkpoint

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FYPO:0007248 - decreased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0005953 - increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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Single locus phenotype

FYPO:0004373 - abnormal mitotic G2 DNA damage checkpoint

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0007247 - abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0004870 - decreased duration of mitotic G2 DNA damage checkpoint

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0004781 - delayed onset of mitotic G2 DNA damage checkpoint

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FYPO:0005953 - increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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