Phenotype ontology term - FYPO:0005781 - decreased duration of mitotic spindle assembly checkpoint
Term summary
- ID
- FYPO:0005781
- Name
- decreased duration of mitotic spindle assembly checkpoint
- Ontology or CV name
- Phenotype
- Definition
- A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic spindle assembly checkpoint is lower than in wild type.
Annotation
Multi-locus phenotype
References:
Genes:
Genotypes:
- bub1+(wild type) bub1+(wild type) spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- bub3delta mph1-delta(1-150)(aa)
- bub3delta spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- hhp1-R261E(aa) hhp2delta nda3-KM311(G93E aa)
- hhp1-R272E,K273E(aa) hhp2delta nda3-KM311(G93E aa)
- mad2+(wild type)[Knockdown] slp1+(wild type)[Overexpression]
- mad2-S92A(aa) mad3-C9A(S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3+(wild type)[Knockdown] slp1+(wild type)[Overexpression]
- mad3-KEN1-AAA(K20A,E21A,N22A aa) slp1+(wild type)[Knockdown]
- slp1+(wild type) slp1-mr63(A131P,F132T aa)[Knockdown]
Single locus phenotype
References:
Genes:
Genotypes:
- apc15delta
- bub3-RA,KA(R201A,K221A aa)
- dma1-C210H,H212A(aa)
- dma1-H88A(aa)
- dma1-R64A(aa)
- dma1delta
- dma1deltaFHA(1-139 Δaa)
- dma1deltaRF(191-268 Δaa)
- mad1+(wild type)[Knockdown]
- mad1+(wild type)[Overexpression]
- mad1-306-676(1-305 Δaa)[Knockdown]
- mad1-458-676(1-457 Δaa)
- mad1-EDD/QNN(E670Q,D673N,D676N aa)
- mad1-ELK/AAA(E670A,L672A,K674A aa)
- mad1-F592A(aa)
- mad1-R593A(aa)
- mad1-deltahelix(662-676 Δaa)
- mad2+(wild type)[Knockdown]
- mad2-4A(S69A,S92A,S187A,S189A aa)
- mad2-5A(S69A,S92A,S187A,T188A,S189A aa)
- mad2-R133A,Q134A(aa)
- mad2-S187D(aa)
- mad2-S189D(aa)
- mad2-S92A(aa)
- mad2-S92D(aa)
- mad2delta
- mad3(1-281)(282-310 Δaa)
- mad3+(wild type)[Knockdown]
- mad3-18A(S19A,S31A,S33A,S38A,S40A,T44A,T64A,T93A,S94A,S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3-ABBA1mut(F242A,V244A,Y245A,D247A aa)
- mad3-ABBA2mut(F299A,V301A,H302A,D304A aa)
- mad3-C9A(S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3-Dbox-mimic(L216K aa)
- mad3-Dbox-mimic-mut(V213A,L216A aa)
- mad3-KEN2-AAA(K271A,E272A,N273A aa)
- mph1-kd(D459A aa)
- mph1delta
- slp1+(wild type)[Overexpression]
- spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- spc7-9TA(T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A aa)
