Phenotype ontology term - FYPO:0006086 - increased mitotic sister chromatid bridge formation during replication fork processing
Term summary
- ID
- FYPO:0006086
- Name
- increased mitotic sister chromatid bridge formation during replication fork processing
- Ontology or CV name
- Phenotype
- Definition
- A cell phenotype in which one or more bridges consisting of unresolved intertwined sister chromatids form following replication fork arrest, and persist until mitotic anaphase. Bridges contain dsDNA and RPA-bound ssDNA, and may break, resulting in unequal sister chromatid segregation.
Annotation
Single locus phenotype
References:
Genes:
Genotypes:
