Phenotype ontology term - FYPO:0006477 - abnormal mitotic metaphase/anaphase transition
Term summary
- ID
- FYPO:0006477
- Name
- abnormal mitotic metaphase/anaphase transition
- Ontology or CV name
- Phenotype
- Definition
- A cellular process phenotype in which the metaphase/anaphase transition of the mitotic cell cycle is abnormal.
Annotation
Multi-locus phenotype
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- TetR-bub1-CD1(TetR-bub1-S381A,T383A,T386A) TetR-mps1
- TetR-bub1-TPR(TetR-bub1(1-240)) TetR-mps1
- TetR-bub1 TetR-mps1 mad1delta
- TetR-bub1 TetR-mps1 mad2delta
- TetR-bub1 TetR-mps1 mad3delta
- TetR-bub1N(TetR-bub1(aa1-325)) TetR-mps1
- alp5-1134(S402N aa) bub1delta
- alp5-1134(S402N aa) mad1delta
- alp5-1134(S402N aa) mad2delta
- alp5-1134(S402N aa) mad3delta
- apc14delta mad2+(wild type)[Overexpression] nda3-311(unknown)
- apc14delta mph1+(wild type)[Overexpression] nda3-311(unknown)
- apc15delta mad2delta nda3-311(unknown)
- apc15delta nda3-311(unknown)
- bub1-KD(K762R,D900N aa) hta1-S121A(S122A aa) hta2-S121A(S122A aa)
- bub1-SATATA(S381A,T383A,T386A aa) mad1-KT-tethered(mad1-mis12 fusion)
- bub1-delta28-160(aa) nda3-KM311(G93E aa)
- bub3delta mad2delta
- bub3delta mph1-delta(1-302)(aa)
- bub3delta mph1delta
- bub3delta nda3-KM311(G93E aa)
- cdc11-119(unknown) cut7-446(I954T aa)
- cnp3C-mph1(cnp3C fusion)[Overexpression] spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- cut7-24(V968A aa) mad2delta
- cut7-24(V968A aa) mad3delta
- hhp2-K41R-7A(K41R,S307A,T309A,T329A,T345A,S358A,S368A,S381A aa) nda3-KM311(G93E aa)
- hta1-S121A(S122A aa) hta2-S121A(S122A aa)
- mad2delta mis6-302(G135E aa)
- mad2delta nda3-311(unknown)
- slp1+(wild type) slp1-mr63(A131P,F132T aa)
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- bub1+(wild type) bub1+(wild type) spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- bub3delta mph1-delta(1-150)(aa)
- bub3delta spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- hhp1-R261E(aa) hhp2delta nda3-KM311(G93E aa)
- hhp1-R272E,K273E(aa) hhp2delta nda3-KM311(G93E aa)
- mad2+(wild type)[Knockdown] slp1+(wild type)[Overexpression]
- mad2-S92A(aa) mad3-C9A(S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3+(wild type)[Knockdown] slp1+(wild type)[Overexpression]
- mad3-KEN1-AAA(K20A,E21A,N22A aa) slp1+(wild type)[Knockdown]
- slp1+(wild type) slp1-mr63(A131P,F132T aa)[Knockdown]
References:
Genes:
Genotypes:
- apc14delta ark1-as3(L166A,S229A,Q28R,Q176R aa) nda3-311(unknown)
- ark1-as3(L166A,S229A,Q28R,Q176R aa) klp5delta klp6delta nda3-KM311(G93E aa)
- ark1-as3(L166A,S229A,Q28R,Q176R aa) klp5delta nda3-KM311(G93E aa)
- ark1-as3(L166A,S229A,Q28R,Q176R aa) klp6delta nda3-KM311(G93E aa)
- dis2delta paa1+(wild type)[Overexpression]
- dis2delta par1+(wild type)[Overexpression]
- dis2delta par2+(wild type)[Overexpression]
- dis2delta ppa1+(wild type)[Overexpression]
- dis2delta ppa2+(wild type)[Overexpression]
- dis2delta ppa3+(wild type)[Overexpression]
References:
Genes:
Genotypes:
- bub1-deltaGLEBS(264-299 Δaa) spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- bub1delta bub3delta spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- bub3delta spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- cnp3C-bub1(cnp3C fusion)[Overexpression] spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- mph1delta spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)
References:
Genes:
Genotypes:
- TetR-D(1-302)Mph1(TetR-mph1delta(1-302))[Ectopic] TetR-spc7(1-666)-9TA(TetR-spc7Δ667-1364-T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A)[Ectopic] mad1-KAKA(K24A,K25A aa)
- TetR-bub1-N700delta(TetR-bub1(1-700)) TetR-mps1
- TetR-bub1 TetR-mps1
- TetR-bub1 TetR-mps1 bub3delta
- TetR-bub1 TetR-mps1 mad1-deltaCC(unknown)
- TetR-bub1 TetR-mps1 spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- alp5-1134(S402N aa) bub3delta
- dis2delta nda3-KM311(G93E aa)
- hhp2-7A(S307A,T309A,T329A,T345A,S358A,S368A,S381A aa) nda3-KM311(G93E aa)
- mad2delta mal2-1(E277K aa)
- mal2-1(E277K aa) mph1delta
- nda3-KM311(G93E aa) sds21delta
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
Single locus phenotype
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- csi1delta
- dma1-I194A(aa)
- dma1-L241A,V245A(aa)
- dma1-L241A(aa)
- dma1-R64A(aa)
- dma1delta
- mad3delta
- sid4N-ppc89C(sid4(1-305)-ppc89(280-783))
- spc7-9MA(M254A,M335A,M363A,M392A,M419A,M450A,M504A,M526A,M549A aa)
- spc7-9TA(T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A aa)
- spc7-9TE(T257E,T338E,T366E,T395E,T422E,T453E,T507E,T529E,T552E aa)
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- TetR-spc7(1-666)-9TA(TetR-spc7Δ667-1364-T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A)
- alp14delta
- alp4-1891(unknown)
- atf1delta
- bub1-KD(K762R,D900N aa)
- bub1-SATATA(S381A,T383A,T386A aa)
- bub1delta
- bub3delta
- dma1delta
- mad1+(wild type)[Overexpression]
- mad1-1-526(527-676 Δaa)
- mad1-1-600(601-676 Δaa)
- mad1-4A(R510A,V511A,L512A,Q513A aa)
- mad1-564-676(1-563 Δaa)
- mad1-585-676(1-584 Δaa)
- mad1-RLK/AAA-KT-tethered(mis12-mad1-RLK-580-AAA)
- mad1-RLK/AAA(R580A,L581A,K582A aa)
- mad1-RLK/ALA(R580A,K582A aa)
- mad1-RL/AG(R510A,L512G aa)
- mad1delta
- mad2+(wild type)[Knockdown]
- mad2-R133A,Q134A(aa)
- mad2-R133A(aa)
- mad2-W74A(aa)
- mad2delta
- mad3-KEN1-AAA(K20A,E21A,N22A aa)
- mis6-302(G135E aa)
- mph1-delta(1-302)(aa)
- nda3-1828(unknown)
- ndc80-AK01(L246P aa)
- nuf2-1(unknown)
- nuf2delta
- rad21-45(I67T aa)
- sgo2delta
- sim4delta
- slp1-mr63(A131P,F132T aa)
References:
Genes:
Genotypes:
- apc15delta
- bub3-RA,KA(R201A,K221A aa)
- dma1-C210H,H212A(aa)
- dma1-H88A(aa)
- dma1-R64A(aa)
- dma1delta
- dma1deltaFHA(1-139 Δaa)
- dma1deltaRF(191-268 Δaa)
- mad1+(wild type)[Knockdown]
- mad1+(wild type)[Overexpression]
- mad1-306-676(1-305 Δaa)[Knockdown]
- mad1-458-676(1-457 Δaa)
- mad1-EDD/QNN(E670Q,D673N,D676N aa)
- mad1-ELK/AAA(E670A,L672A,K674A aa)
- mad1-F592A(aa)
- mad1-R593A(aa)
- mad1-deltahelix(662-676 Δaa)
- mad2+(wild type)[Knockdown]
- mad2-4A(S69A,S92A,S187A,S189A aa)
- mad2-5A(S69A,S92A,S187A,T188A,S189A aa)
- mad2-R133A,Q134A(aa)
- mad2-S187D(aa)
- mad2-S189D(aa)
- mad2-S92A(aa)
- mad2-S92D(aa)
- mad2delta
- mad3(1-281)(282-310 Δaa)
- mad3+(wild type)[Knockdown]
- mad3-18A(S19A,S31A,S33A,S38A,S40A,T44A,T64A,T93A,S94A,S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3-ABBA1mut(F242A,V244A,Y245A,D247A aa)
- mad3-ABBA2mut(F299A,V301A,H302A,D304A aa)
- mad3-C9A(S246A,S251A,T259A,T262A,T265A,S276A,T278A,S279A,S289A aa)
- mad3-Dbox-mimic(L216K aa)
- mad3-Dbox-mimic-mut(V213A,L216A aa)
- mad3-KEN2-AAA(K271A,E272A,N273A aa)
- mph1-kd(D459A aa)
- mph1delta
- slp1+(wild type)[Overexpression]
- spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
- spc7-9TA(T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A aa)
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- bub1-P*(T340A,T423A,T455A,S466A aa)
- bub1-deltaGLEBS(264-299 Δaa)
- bub1delta
- bub3delta
- cnp3C-bub1(cnp3C fusion)[Overexpression]
- mph1delta
- spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)
- spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
References:
Genes:
Genotypes:
References:
Genes:
Genotypes:
- alm1delta
- alp11-924(W119*)
- alp14delta
- alp7-5A-b(K341A,Y344A,R346A,K347A,Y348A aa)
- alp7-LA6(L380A,L387A,L391A,L405A,L418A,L419A aa)
- alp7delta
- arp3-c1(G334S aa)
- ase1delta
- asp1-D333A(aa)
- cam1-E14(E69V,E106V aa)
- cnp3-T28E(aa)
- dad2delta
- dam1delta
- dcn1delta
- dis2delta
- edc1delta
- fkh2delta
- klp5-Q582P(aa)
- klp5delta
- klp6+(wild type)[Overexpression]
- klp6delta
- klp9-delta38C(596-633 Δaa)
- klp9delta
- mal2-1(E277K aa)
- mal3delta
- mto1delta
- ndc80-21(T307A,E379G,L405P aa)
- nsk1delta
- pad1-1(G54S aa)
- par1-S378A(aa)
- pdk1delta
- pim1-F201S(aa)
- pkl1delta
- spc7-9MA,9TA(M254A,T257A,M335A,T338A,M363A,T366A,M392A,T395A,M419A,T422A,M450A,T453A,M504A,T507A,M526A,T529A,M549A,T552A aa)
- spc7-9MA(M254A,M335A,M363A,M392A,M419A,M450A,M504A,M526A,M549A aa)
- spc7-9TA(T257A,T338A,T366A,T395A,T422A,T453A,T507A,T529A,T552A aa)
- ubc11-P93L(aa)
- wee1delta
References:
Genes:
Genotypes:
