GO biological process ontology term - GO:0000086 - G2/M transition of mitotic cell cycle
Term summary
- ID
- GO:0000086
- Name
- G2/M transition of mitotic cell cycle
- Ontology or CV name
- GO biological process
- Definition
- The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.