GO biological process ontology term - GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Term summary
- ID
- GO:0000184
- Name
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
- Ontology or CV name
- GO biological process
- Definition
- The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.