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GO biological process ontology term - GO:0000377 - RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

Term summary

ID
GO:0000377
Name
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
Ontology or CV name
GO biological process
Definition
Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.

Parents

Annotation

GO biological process

GO:0000380 - alternative mRNA splicing, via spliceosome

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GO:0000354 - cis assembly of pre-catalytic spliceosome

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GO:0000349 - generation of catalytic spliceosome for first transesterification step

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GO:0000350 - generation of catalytic spliceosome for second transesterification step

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GO:0000389 - mRNA 3'-splice site recognition

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GO:0000395 - mRNA 5'-splice site recognition

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GO:0000348 - mRNA branch site recognition

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GO:0045292 - mRNA cis splicing, via spliceosome

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GO:0006376 - mRNA splice site recognition

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GO:0000398 - mRNA splicing, via spliceosome

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GO:1905746 - positive regulation of mRNA cis splicing, via spliceosome

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GO:0048026 - positive regulation of mRNA splicing, via spliceosome

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GO:0000381 - regulation of alternative mRNA splicing, via spliceosome

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GO:1905744 - regulation of mRNA cis splicing, via spliceosome

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GO:0048024 - regulation of mRNA splicing, via spliceosome

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GO:0000245 - spliceosomal complex assembly

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GO:0000390 - spliceosomal complex disassembly

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GO:0000393 - spliceosomal conformational changes to generate catalytic conformation

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GO:0000387 - spliceosomal snRNP assembly

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GO:0000244 - spliceosomal tri-snRNP complex assembly

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GO:0000388 - spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

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GO:1903241 - U2-type prespliceosome assembly

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