GO molecular function ontology term - GO:0000386 - second spliceosomal transesterification activity
Term summary
- ID
- GO:0000386
- Name
- second spliceosomal transesterification activity
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
