GO cellular component ontology term - GO:0000836 - Hrd1p ubiquitin ligase complex
Term summary
- ID
- GO:0000836
- Name
- Hrd1p ubiquitin ligase complex
- Ontology or CV name
- GO cellular component
- Definition
- A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
