GO molecular function ontology term - GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Term summary
- ID
- GO:0003918
- Name
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
