GO molecular function ontology term - GO:0003994 - aconitate hydratase activity
Term summary
- ID
- GO:0003994
- Name
- aconitate hydratase activity
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.