GO cellular component ontology term - GO:0005680 - anaphase-promoting complex
Term summary
- ID
- GO:0005680
- Name
- anaphase-promoting complex
- Ontology or CV name
- GO cellular component
- Definition
- A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
