GO cellular component ontology term - GO:0005757 - mitochondrial permeability transition pore complex
Term summary
- ID
- GO:0005757
- Name
- mitochondrial permeability transition pore complex
- Ontology or CV name
- GO cellular component
- Definition
- A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).