GO cellular component ontology term - GO:0005834 - heterotrimeric G-protein complex
Term summary
- ID
- GO:0005834
- Name
- heterotrimeric G-protein complex
- Ontology or CV name
- GO cellular component
- Definition
- Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.
