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GO biological process ontology term - GO:0006281 - DNA repair

Term summary

ID
GO:0006281
Name
DNA repair
Ontology or CV name
GO biological process
Definition
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

Parents

Annotation

GO biological process

GO:0006281 - DNA repair

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GO:0006281 - DNA repair

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GO:0006284 - base-excision repair

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GO:0006285 - base-excision repair, AP site formation

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GO:0097510 - base-excision repair, AP site formation via deaminated base removal

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GO:0006287 - base-excision repair, gap-filling

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GO:0045007 - depurination

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GO:0006307 - DNA alkylation repair

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GO:0000729 - DNA double-strand break processing

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GO:0000730 - DNA recombinase assembly

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GO:0045004 - DNA replication proofreading

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GO:0000731 - DNA synthesis involved in DNA repair

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GO:1904161 - DNA synthesis involved in UV-damage excision repair

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GO:0006302 - double-strand break repair

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GO:1990918 - double-strand break repair involved in meiotic recombination

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GO:0000727 - double-strand break repair via break-induced replication

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GO:0097680 - double-strand break repair via classical nonhomologous end joining

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GO:0000724 - double-strand break repair via homologous recombination

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GO:0006303 - double-strand break repair via nonhomologous end joining

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GO:0045002 - double-strand break repair via single-strand annealing

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GO:0000736 - double-strand break repair via single-strand annealing, removal of nonhomologous ends

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GO:0045003 - double-strand break repair via synthesis-dependent strand annealing

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GO:0061674 - gap filling involved in double-strand break repair via nonhomologous end joining

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GO:0070911 - global genome nucleotide-excision repair

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GO:0036297 - interstrand cross-link repair

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GO:0000706 - meiotic DNA double-strand break processing

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GO:0000707 - meiotic DNA recombinase assembly

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GO:0010772 - meiotic DNA recombinase assembly involved in reciprocal meiotic recombination

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GO:0000710 - meiotic mismatch repair

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GO:1902346 - meiotic strand displacement involved in double-strand break repair via SDSA

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GO:0006298 - mismatch repair

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GO:0070716 - mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication

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GO:0043504 - mitochondrial DNA repair

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GO:2001033 - negative regulation of double-strand break repair via nonhomologous end joining

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GO:0036299 - non-recombinational interstrand cross-link repair

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GO:0006289 - nucleotide-excision repair

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GO:1901255 - nucleotide-excision repair involved in interstrand cross-link repair

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GO:0006297 - nucleotide-excision repair, DNA gap filling

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GO:0006294 - nucleotide-excision repair, preincision complex assembly

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GO:0045739 - positive regulation of DNA repair

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GO:2000781 - positive regulation of double-strand break repair

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GO:1905168 - positive regulation of double-strand break repair via homologous recombination

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GO:2001034 - positive regulation of double-strand break repair via nonhomologous end joining

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GO:0106300 - protein-DNA covalent cross-linking repair

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GO:0006290 - pyrimidine dimer repair

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GO:0000720 - pyrimidine dimer repair by nucleotide-excision repair

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GO:0036298 - recombinational interstrand cross-link repair

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GO:0000725 - recombinational repair

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GO:0006282 - regulation of DNA repair

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GO:2000779 - regulation of double-strand break repair

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GO:0010569 - regulation of double-strand break repair via homologous recombination

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GO:1990414 - replication-born double-strand break repair via sister chromatid exchange

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GO:1990516 - ribonucleotide excision repair

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GO:0000012 - single strand break repair

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GO:0006283 - transcription-coupled nucleotide-excision repair

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GO:0070914 - UV-damage excision repair

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