GO biological process ontology term - GO:0006370 - 7-methylguanosine mRNA capping
Term summary
- ID
- GO:0006370
- Name
- 7-methylguanosine mRNA capping
- Ontology or CV name
- GO biological process
- Definition
- The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.
