GO biological process ontology term - GO:0006614 - SRP-dependent cotranslational protein targeting to membrane
Term summary
- ID
- GO:0006614
- Name
- SRP-dependent cotranslational protein targeting to membrane
- Ontology or CV name
- GO biological process
- Definition
- The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.