GO biological process ontology term - GO:0006898 - receptor-mediated endocytosis
Term summary
- ID
- GO:0006898
- Name
- receptor-mediated endocytosis
- Ontology or CV name
- GO biological process
- Definition
- An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
