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GO biological process ontology term - GO:0007091 - metaphase/anaphase transition of mitotic cell cycle

Term summary

ID
GO:0007091
Name
metaphase/anaphase transition of mitotic cell cycle
Ontology or CV name
GO biological process
Definition
The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

Parents

Annotation

GO biological process

GO:0007091 - metaphase/anaphase transition of mitotic cell cycle

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Genes:

GO:1902426 - deactivation of mitotic spindle assembly checkpoint

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GO:0007094 - mitotic spindle assembly checkpoint signaling

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GO:0045841 - negative regulation of mitotic metaphase/anaphase transition

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GO:0140499 - negative regulation of mitotic spindle assembly checkpoint signaling

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GO:0090267 - positive regulation of mitotic cell cycle spindle assembly checkpoint

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GO:0045842 - positive regulation of mitotic metaphase/anaphase transition

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Genes:

GO:0090266 - regulation of mitotic cell cycle spindle assembly checkpoint

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