GO cellular component ontology term - GO:0016272 - prefoldin complex
Term summary
- ID
- GO:0016272
- Name
- prefoldin complex
- Ontology or CV name
- GO cellular component
- Definition
- A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
