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GO molecular function ontology term - GO:0016829 - lyase activity

Term summary

ID
GO:0016829
Name
lyase activity
Ontology or CV name
GO molecular function
Definition
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

Parents

Annotation

GO molecular function

GO:0019171 - (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

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Genes:

GO:0070626 - (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity

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GO:0106359 - 2-hydroxyacyl-CoA lyase activity

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GO:0106334 - 3'-deoxyribose phosphate lyase activity

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GO:0008686 - 3,4-dihydroxy-2-butanone-4-phosphate synthase activity

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GO:0003855 - 3-dehydroquinate dehydratase activity

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GO:0003856 - 3-dehydroquinate synthase activity

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GO:0003861 - 3-isopropylmalate dehydratase activity

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GO:0008696 - 4-amino-4-deoxychorismate lyase activity

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GO:0120539 - 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity

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GO:0051575 - 5'-deoxyribose-5-phosphate lyase activity

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GO:0003994 - aconitate hydratase activity

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GO:0004014 - adenosylmethionine decarboxylase activity

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GO:0004016 - adenylate cyclase activity

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GO:0016832 - aldehyde-lyase activity

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GO:0004049 - anthranilate synthase activity

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GO:0004056 - argininosuccinate lyase activity

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GO:0047453 - ATP-dependent NAD(P)H-hydrate dehydratase activity

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GO:0016840 - carbon-nitrogen lyase activity

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GO:0016846 - carbon-sulfur lyase activity

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GO:0004089 - carbonate dehydratase activity

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GO:0004107 - chorismate synthase activity

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GO:0140078 - class I DNA-(apurinic or apyrimidinic site) endonuclease activity

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GO:0047804 - cysteine-S-conjugate beta-lyase activity

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GO:0019148 - D-cysteine desulfhydrase activity

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GO:0047820 - D-glutamate cyclase activity

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GO:0008721 - D-serine ammonia-lyase activity

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GO:0004150 - dihydroneopterin aldolase activity

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GO:0004160 - dihydroxy-acid dehydratase activity

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GO:0004163 - diphosphomevalonate decarboxylase activity

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GO:0008460 - dTDP-glucose 4,6-dehydratase activity

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GO:0097023 - fructose 6-phosphate aldolase activity

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GO:0004332 - fructose-bisphosphate aldolase activity

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GO:0004333 - fumarate hydratase activity

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GO:0061928 - glutathione specific gamma-glutamylcyclotransferase activity

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GO:0019172 - glyoxalase III activity

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GO:1990411 - hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)

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GO:0004408 - holocytochrome-c synthase activity

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GO:0004409 - homoaconitate hydratase activity

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GO:0016836 - hydro-lyase activity

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GO:0004424 - imidazoleglycerol-phosphate dehydratase activity

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GO:0004425 - indole-3-glycerol-phosphate synthase activity

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GO:0004451 - isocitrate lyase activity

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GO:0008732 - L-allo-threonine aldolase activity

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GO:0003941 - L-serine ammonia-lyase activity

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GO:0004462 - lactoylglutathione lyase activity

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GO:0046421 - methylisocitrate lyase activity

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GO:0046570 - methylthioribulose 1-phosphate dehydratase activity

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GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

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GO:0051009 - O-acetylhomoserine sulfhydrylase activity

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GO:0004586 - ornithine decarboxylase activity

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GO:0004590 - orotidine-5'-phosphate decarboxylase activity

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GO:0008948 - oxaloacetate decarboxylase activity

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GO:0004609 - phosphatidylserine decarboxylase activity

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GO:0004633 - phosphopantothenoylcysteine decarboxylase activity

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GO:0004634 - phosphopyruvate hydratase activity

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GO:0004638 - phosphoribosylaminoimidazole carboxylase activity

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GO:0004655 - porphobilinogen synthase activity

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GO:0004664 - prephenate dehydratase activity

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GO:0004325 - protoporphyrin ferrochelatase activity

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GO:0004730 - pseudouridylate synthase activity

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GO:0036381 - pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity

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GO:0004737 - pyruvate decarboxylase activity

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GO:0051907 - S-(hydroxymethyl)glutathione synthase activity

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GO:0051266 - sirohydrochlorin ferrochelatase activity

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GO:0004794 - threonine deaminase activity

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GO:0004795 - threonine synthase activity

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GO:0061503 - tRNA threonylcarbamoyladenosine dehydratase activity

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GO:0102521 - tRNA-4-demethylwyosine synthase activity

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GO:0000213 - tRNA-intron lyase activity

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GO:0004834 - tryptophan synthase activity

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GO:0050377 - UDP-glucose 4,6-dehydratase activity

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GO:0050385 - ureidoglycolate lyase activity

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GO:0004853 - uroporphyrinogen decarboxylase activity

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GO:0004852 - uroporphyrinogen-III synthase activity

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GO:0102158 - very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

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