GO molecular function ontology term - GO:0017136 - histone deacetylase activity, NAD-dependent
Term summary
- ID
- GO:0017136
- Name
- histone deacetylase activity, NAD-dependent
- Ontology or CV name
- GO molecular function
- Definition
- Catalysis of the reaction: N(6)-acetyl-L-lysyl-[histone] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a histone to NAD, producing nicotinamide.
