GO cellular component ontology term - GO:0019005 - SCF ubiquitin ligase complex
Term summary
- ID
- GO:0019005
- Name
- SCF ubiquitin ligase complex
- Ontology or CV name
- GO cellular component
- Definition
- A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
