GO cellular component ontology term - GO:0030014 - CCR4-NOT complex
Term summary
- ID
- GO:0030014
- Name
- CCR4-NOT complex
- Ontology or CV name
- GO cellular component
- Definition
- The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.