GO cellular component ontology term - GO:0031298 - replication fork protection complex
Term summary
- ID
- GO:0031298
- Name
- replication fork protection complex
- Ontology or CV name
- GO cellular component
- Definition
- A heterotrimeric replication-pausing complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. Required for maximal fork speed both in vivo and in vitro.
