GO cellular component ontology term - GO:0031511 - Mis6-Sim4 complex
Term summary
- ID
- GO:0031511
- Name
- Mis6-Sim4 complex
- Ontology or CV name
- GO cellular component
- Definition
- A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.
