GO cellular component ontology term - GO:0032783 - super elongation complex
Term summary
- ID
- GO:0032783
- Name
- super elongation complex
- Ontology or CV name
- GO cellular component
- Definition
- A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.
