GO cellular component ontology term - GO:0033597 - mitotic checkpoint complex
Term summary
- ID
- GO:0033597
- Name
- mitotic checkpoint complex
- Ontology or CV name
- GO cellular component
- Definition
- A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.
