GO cellular component ontology term - GO:0035267 - NuA4 histone acetyltransferase complex
Term summary
- ID
- GO:0035267
- Name
- NuA4 histone acetyltransferase complex
- Ontology or CV name
- GO cellular component
- Definition
- A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).
