GO biological process ontology term - GO:0036503 - ERAD pathway
Term summary
- ID
- GO:0036503
- Name
- ERAD pathway
- Ontology or CV name
- GO biological process
- Definition
- The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
