GO cellular component ontology term - GO:0042721 - TIM22 mitochondrial import inner membrane insertion complex
Term summary
- ID
- GO:0042721
- Name
- TIM22 mitochondrial import inner membrane insertion complex
- Ontology or CV name
- GO cellular component
- Definition
- A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.