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GO biological process ontology term - GO:0045047 - protein targeting to ER

Term summary

ID
GO:0045047
Name
protein targeting to ER
Ontology or CV name
GO biological process
Definition
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.

Parents

Annotation

GO biological process

GO:0045047 - protein targeting to ER

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GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane

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GO:0031204 - post-translational protein targeting to membrane, translocation

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GO:0006614 - SRP-dependent cotranslational protein targeting to membrane

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GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

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GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation

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