GO cellular component ontology term - GO:0045254 - pyruvate dehydrogenase complex
Term summary
- ID
- GO:0045254
- Name
- pyruvate dehydrogenase complex
- Ontology or CV name
- GO cellular component
- Definition
- A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.
